Endocrine Abstracts

Ghrelin is a peptide predominantly produced by the stomach although expressed by many other tissues. Its secretion undergoes fluctuations, is stimulated by fasting and energy restriction, reduced by food intake, glucose, insulin and somatostatin. Ghrelin secretion is negatively associated to body mass. Ghrelin was discovered as natural ligand of the GHS1a receptor specific for synthetic GH Secretagogues (GHS); however, ghrelin is much more than a natural GHS. GHS-R1a expressio...

Ezio Ghigo, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Molinette Hospital, C.so Dogliotti 14, 10126 Torino, Italy AbstractEzio Ghigo graduated in Medicine from the University of Turin in 1979 and received his postgraduate qualification in Endocrinology and Metabolism in 1982. He became a Full Professor of Endocrinology and Metabolism in 1999 and has been Chairman of ...