Endocrine Abstracts

Introduction: Hybrid closed loop pumps (HCL) incorporate insulin pumps (IPs) with continuous glucose monitoring (CGM). Basal and bolus insulin release can be algorithmically adjusted in real-time enabling some automated insulin changes between meals according to set parameters. We reviewed the glycaemic control of patients with T1D cared for at the Evelina who had upgraded from IP to HCL between October 2020 and January 2022.Methods: As per standard care...

Introduction: There were concerns voiced by health care professionals (HCPs) that restrictions to healthcare delivery during the pandemic has resulted in delays in diagnosing T1D in CYP. Most CYP present with symptoms of T1D to primary care. Delay in diagnosis increases the risk of potentially life-threatening diabetic ketoacidosis (DKA). In Cardiff, we piloted QI initiatives pre-pandemic to improve early diagnosis which was introduced across the Children and Young People&#146...

Introduction: Children and young people with T1DM living in the least deprived areas have better diabetes control vs those in most deprived areas with UK NPDA data suggesting that deprivation and ethnicity are associated with less use of technology.1Aims: 1. Review distribution of technology between different socio-economic and ethnic groups 2. To compare mean recent HbA1c results between groups using different combinations of technology<p...

Introduction: Managing diabetes in a child is complex and demanding for parents, for some families this is exacerbated by additional demands. Compromised family capacity may lead to diminished management of a child’s diabetes, increasing the risk for acute and long-term complications. The UK has the highest rates in Europe of children (0-14years) living with Type 1 diabetes (International Diabetes Federation, 2019) however, it is concerning that less than 40% have a HbA1c...

Introduction: The pandemic resulted in changes in delivery of healthcare. Most children and young people (CYP) present with symptoms of T1D for the first time to primary care. Delayed diagnosis is common and associated with risk of life-threatening diabetic ketoacidosis (DKA). In Cardiff, we had a pre-pandemic QI project to improve early diagnosis of T1D. We escalated responses, introduced initiatives to facilitate early diagnosis.Aim: To develop effecti...

Background: NICE guidance (NG18) and East & North Hertfordshire NHS Trust (ENHT) CG048 recommend that in order to prevent macrovascular cardiovascular disease, services for Children and Young People with Diabetes (CYPD) offer monitoring annually from 12 years for microalbuminuria (to detect diabetic kidney disease), hypertension and dyslipidaemia. Anecdotally, elevated blood pressure (BP) readings in clinic were often attributed to anxiety or an incorrect cuff size and wer...

Keywords: COVID-19, Diabetes Mellitus, PaediatricsIntroduction: COVID-19 has a complex relationship with diabetes. There is anecdotal evidence that it could be causative for new onset diabetes in paediatrics. In this audit, we aim to study our cohort of new onset diabetes in children and young people (CYP) during the COVID pandemic in a DGH setting. We sought to identify any causative or associational link between COVID-19 and new onset diabetes.<p c...

AimsTo present a case of steroid induced diabetes and use this opportunity to review the diabetic resources we provide to other speciality teams in our hospital. CaseA fifteen year old patient was diagnosed with acute lymphoblastic leukaemia from a full blood count and bone marrow biopsy following a short history of lymph node swelling. He was started on a treatment regime that included dexamethasone at a dose of 6mg/m2</...

Background: Type 1 diabetes (T1D) is a metabolic disease of unknown aetiology that results from the autoimmune destruction of the insulin-producing pancreatic β-cells. Exogenous insulin administration is the only treatment for patients. Partial remission or “honeymoon phase” classically occurs a few weeks after insulin therapy has been initiated. During this stage the patient’s need for exogenous insulin can decline by 50%, and near-normal metabolic control...