Endocrine Abstracts

Contents

• CME Training Day
• • CME Training Day Sessions
  • CME Symposium 1
  • • Abstract unavailable

      ea0085cme1.1
    • Abstract unavailable

      ea0085cme1.2
  • CME Symposium 2
  • • An approach to hypo/hypercalcemia

      ea0085cme2.1
    • Abstract unavailable

      ea0085cme2.2
  • CME Symposium 3
  • • Genetic approach to Short stature

      ea0085cme3.1
    • Neonatal diabetes

      ea0085cme3.2
  • CME Symposium 4
  • • Abstract unavailable

      ea0085cme4.1
• Endocrine Main Meeting Sessions
• • Endocrine Symposium 1
  • • Congenital imprinting disorders

      ea0085emm1.1
    • Abstract unavailable

      ea0085emm1.2
  • Endocrine Symposium 2
  • • BSPED consensus guidelines: emergency and peri-operative management of adrenal insufficiency in children and young people

      ea0085emm2.1
    • Abstract unavailable

      ea0085emm2.2
• Diabetes Professionals Day Sessions
• • Diabetes and COVID Symposium
  • • Diabetes and covid symposium: introduction and the south east thames study

      ea0085dpd1.1
    • Paediatric diabetes and SARS-CoV-2 - a riddle wrapped in a mystery inside an enigma

      ea0085dpd1.2
    • Abstract unavailable

      ea0085dpd1.3
    • 'Proving causation?': antibody studies in covid related diabetes

      ea0085dpd1.4
    • Abstract unavailable

      ea0085dpd1.5
    • Abstract unavailable

      ea0085dpd1.6
  • Diabetes Symposium 2
  • • The Impact of diabetic ketoacidosis on glycaemic control

      ea0085dpd2.1
    • The big fat question - lipids and glycaemia

      ea0085dpd2.2
  • Diabetes Symposium 3
  • • Abstract unavailable

      ea0085dpd3.1
    • Abstract unavailable

      ea0085dpd3.2
  • Personal Practice Session
  • • Abstract unavailable

      ea0085dpd4.1
    • CHOICE - structured diabetes education programme for children and young people in Northern Ireland

      ea0085dpd4.2
• Diabetes Main Day Sessions
• • Diabetes Symposium 4
  • • Abstract unavailable

      ea0085dmd1.1
    • Closed-loop system data review: universal approaches for treatment optimisation

      ea0085dmd1.2
    • Developing an early stage treatment for diabetic retinopathy

      ea0085dmd1.3
  • Diabetes Symposium 5
  • • Abstract unavailable

      ea0085dmd2.1
    • Abstract unavailable

      ea0085dmd2.2
    • Developing an early stage treatment for diabetic retinopathy

      ea0085dmd1.3
• Nurses' Day for Endocrine Professionals Sessions
• • Endocrine Symposium 3
  • • CAH & adolescent gynaecology - an MDT perspective

      ea0085nep1.1
    • Abstract unavailable

      ea0085nep1.2
    • 'Handing over the reins'- CAH and adolescence from a parent's perspective

      ea0085nep1.3
  • Endocrine Symposium 4
  • • Immune dysregulation driving future risk of disease in children with obesity

      ea0085nep2.1
    • Abstract unavailable

      ea0085nep2.2
    • Abstract unavailable

      ea0085nep2.3
• Oral Communications
• • Oral Communications 1
  • • Defects in QSOX2, a novel regulator of STAT5B nuclear import and transcriptional activity, lead to severe post-natal growth restriction

      ea0085oc1.1
    • A rare case of short stature with high total insulin like growth factor 1 (IGF-1) and a novel pregnancy-associated plasma protein A2 (PAPPA2) gene mutation

      ea0085oc1.2
  • Oral Communications 2
  • • Coeliac disease presenting with anti-OPG antibody mediated childhood osteoporosis and response to bisphosphonate therapy

      ea0085oc2.1
    • The missing segment from the age of enlightenment

      ea0085oc2.2
  • Oral Communications 3
  • • A rare form of ovotesticular difference of sex development (DSD) in combination with severe early-onset obesity due to MC4R mutation: clinical features and diagnostic challenges

      ea0085oc3.1
    • Two cases on the carney complex spectrum secondary to PRKACA/PRKAR1A variants presenting with cushing syndrome in childhood

      ea0085oc3.2
  • Oral Communications 4
  • • Pseudohypoaldosteronism case series

      ea0085oc4.1
    • Treatment-induced neuropathy of diabetes: a case report

      ea0085oc4.2
  • Oral Communications 5
  • • Can lymphocyte subsets and B cell cytokines predict clinical response to Rituximab in paediatric graves' disease?

      ea0085oc5.1
    • Central Delayed Puberty in Adolescence: Differentiating the phenotypes of Congenital Hypogonadotropic Hypogonadism and Self-Limited Delayed Puberty

      ea0085oc5.2
    • UK protocol for induction of puberty with gonadotropins in males with hypogonadotropic hypogonadism

      ea0085oc5.3
    • Greater postnatal adiposity gain following inadequate fetal growth in the manchester babyGRO study

      ea0085oc5.4
    • The lack of genotype: phenotype correlations in rare causes of primary adrenal insufficiency highlights the need for genetic testing

      ea0085oc5.5
    • Prevalence of overweight and obesity in children with bone fragility and its correlation with disease severity and fracture rate

      ea0085oc5.6
    • Salivary cortisol and cortisone in healthy children and young people

      ea0085oc5.7
    • SGPL1 deficiency impairs Leydig cell steroidogenesis and should be considered in 46XY individuals with DSD and adrenal insufficiency

      ea0085oc5.8
    • Evaluation of a low postnatal hypoglycaemia threshold

      ea0085oc5.9
  • Oral Communications 6
  • • Pubertal staging examinations: a national survey of current practice in consent and chaperone use

      ea0085oc6.1
    • The Arginine-nitric-oxide pathway links suboptimal fetal growth to higher childhood systolic blood pressure in the manchester babyGRO study

      ea0085oc6.2
    • Use of 24 weekly decapeptyl SR in central precocious puberty is well-tolerated and efficacious - a two centre study

      ea0085oc6.3
    • A Collaborative community based approach in providing support for children and young people with severe obesity

      ea0085oc6.4
    • Bone mineralisation as assessed by bone health index in children with congenital adrenal hyperplasia

      ea0085oc6.5
  • Oral Communications 7
  • • Comparison of outcomes of the hybrid closed loop therapy with the conventional insulin pump in the first year after pump initiation

      ea0085oc7.1
    • Self-collection of capillary blood samples at home for HbA1c measurements during the COVID-19 pandemic in children with diabetes mellitus

      ea0085oc7.2
    • Hypogonadism and pubertal disorders in wolfram syndrome

      ea0085oc7.3
    • Type A insulin resistance syndrome presenting with PCOS features and an unusual pattern of diabetes in a 10-year-old female

      ea0085oc7.4
    • Monogenic obesity is probably not so rare - experience from a large tier 3 paediatric weight management service

      ea0085oc7.5
  • Oral Communications 8
  • • Do we need earlier thyroid surveillance amongst PTEN patients in the UK?

      ea0085oc8.1
    • Endocrine effects of MEK and BRAF inhibitor therapy in paediatric patients: a tertiary centre experience

      ea0085oc8.2
    • Characterisation of the first heterozygous missense HMGA2 variant helps delineate the crucial functional roles of a novel growth gene

      ea0085oc8.3
    • A national survey of bone-endocrine monitoring in duchenne muscular dystrophy and the patients experience

      ea0085oc8.4
    • Contrast media-induced hypothyroidism

      ea0085oc8.5
  • Oral Communications 9
  • • Access and use of new technologies in diabetes care in patients that need an interpreter compared to those that do not

      ea0085oc9.1
    • Audit of management of diabetic ketoacidosis in children at The Noah’s Ark Children’s Hospital for Wales

      ea0085oc9.2
    • Diabetes and obesity in down syndrome across the lifespan: a retrospective cohort study using UK electronic health records

      ea0085oc9.3
    • Do the UK's commercially available real-time continuous glucose monitoring devices have robust accuracy data for paediatrics?

      ea0085oc9.4
    • Raising awareness of the importance of preconception counselling in young people with diabetes

      ea0085oc9.5
    • A review of patient outcomes and responses to weight management strategies used by complications from excess weight service, a new paediatric, hospital-based weight management service

      ea0085oc9.6
    • Liraglutide for the treatment of severe obesity in children: early experiences from a tier 3 paediatric weight management service

      ea0085oc9.7
    • Cyclic improvement of a structured education programme teaching dynamic glucose management strategies in children and young people with type 1 diabetes using continuous glucose monitoring

      ea0085oc9.8
  • Oral Communications 10
  • • Hormone replacement therapy in paediatric turner syndrome - evaluation of current practice in a dedicated paediatric turner clinic and subsequent development of patient resources

      ea0085oc10.1
    • Patient and parent experiences with oral hydrocortisone formulations for adrenal insufficiency

      ea0085oc10.2
    • Development and testing of a novel 'Growth monitor' Smartphone App for growth monitoring and the detection of growth disorders

      ea0085oc10.3
    • Increasing patient adherence and reducing drug wastage: impact of a personalised patient support programme integrated with a digital connect ecosystem

      ea0085oc10.4
    • Factors affecting the hypoglycaemic response in the insulin tolerance test in paediatric patients

      ea0085oc10.5
    • A comparative study observing the association between graves' disease and the covid-19 pandemic in children

      ea0085oc10.6
• Poster Presentations
• • Adrenal 1
  • • Recommendations for hydrocortisone doses for emergency management and peri-operative care for childhood adrenal insufficiency. BSPED consensus guidelines

      ea0085p1
    • Salivary adrenal biomarkers differ depending on age and sex in healthy children: preliminary data

      ea0085p2
    • Mean glucose concentrations are increased, and cardiovascular risk factors are common in children and young people with secondary adrenal insufficiency (GRACE2)

      ea0085p3
    • Establishing the utility of the 60-minute serum cortisol sample in a standard synacthen test in a tertiary paediatric centre

      ea0085p4
    • Abstract unavailable

      ea0085p5
    • Abstract Unavailable

      ea0085p6
  • Bone
  • • Does maternal deprivation have a bearing on the newborn vitamin D status?

      ea0085p7
    • Burden of disease in family members of children presenting with symptomatic vitamin D deficiency: who to test and when?

      ea0085p8
    • Bone biochemistry in children with fractures presenting with non-accidental injury

      ea0085p9
    • Hypophosphatemic rickets as a key presenting feature of tyrosinemia type 1

      ea0085p10
    • Abstract unavailable

      ea0085p11
    • A case series of 8 patients with pseudohypoparathyroidism and variable phenotype

      ea0085p12
    • Atypical persistence of neuropsychiatric symptoms in adolescents with primary hyperparathyroidism post parathyroidectomy- a review of two cases

      ea0085p13
    • A novel GNAS variant in a child with hyperphagia, obesity, brachydactyly and normocalcaemia

      ea0085p14
  • Diabetes 1
  • • Blindness at initial presentation of new onset diabetes mellitus in a 13 year old girl

      ea0085p15
    • Generic standard operating procedure (SOP) for insulin dose adjustment

      ea0085p16
    • Is there an increased incidence of type 1 diabetes in correlation with SARS- COVID 19 infection?- an east of england network survey

      ea0085p17
    • Type 2 diabetes mellitus in children and young people; Single UK paediatric diabetes centre experience

      ea0085p18
    • An unanticipated complication following diabetic ketoacidosis treatment

      ea0085p19
    • A review of our diabetes transition service: clinic attendance, average HbA1c and hospital admissions in patients between the ages of 15 to 21 years old

      ea0085p20
    • Using language to empower joint diabetes decision making in the paediatric diabetes clinic

      ea0085p21
    • Paediatric diabetes practice overview at a DGH hospital of east midlands deanery

      ea0085p22
  • Gonadal, DSD and Reproduction
  • • The prevalence of hypertension in children and adolescents with turner syndrome: a systematic review and meta-analysis

      ea0085p23
    • A tale of 2 syndromes

      ea0085p24
    • Salivary cortisol is increased in paediatric patients with turner syndrome, and the circadian rhythm is blunted: preliminary data from a pilot study

      ea0085p25
    • Gonadotrophin independent puberty (GIPP) with unusually high oestradiol level in an infant with mccune albright syndrome (MAS)

      ea0085p26
    • Delayed puberty is very common in boys with duchenne muscular dystrophy on daily glucocorticoid-implications for management and age to initiate testosterone

      ea0085p27
    • Extreme overgrowth resulting from exposure to exogenous testosterone gel in a young boy

      ea0085p28
  • Miscellaneous 1
  • • Trametinib induced hyponatraemia in a patient with craniopharyngioma and diabetes insipidus

      ea0085p29
    • Risk of post-treatment hypothyroidism in paediatric neuroblastoma

      ea0085p30
    • Clinical features of multiple endocrine neoplasia type 1 in children

      ea0085p31
    • Service evaluation of girls with complex disability presenting with concerns regarding puberty

      ea0085p32
    • Cardiac imaging in a dedicated paediatric turner syndrome clinic

      ea0085p33
    • Digitising patient information leaflets using QR codes

      ea0085p34
    • A Perfect storm: multisystem endocrine disorders in a girl with T21

      ea0085p35
  • Obesity 1
  • • Percentage excess weight and risk of co-morbidity in obese children

      ea0085p36
    • Obesity in glucocorticoid treated boys with duchenne muscular dystrophy: a need for structured nutritional-metabolic assessment and pro-active management

      ea0085p37
    • A questionnaire-based baseline evaluation of hunger in UK adolescents with severe obesity

      ea0085p38
    • Baseline body composition of adolescents attending a UK tertiary weight management service

      ea0085p39
    • Thrombocytopenia in a patient on antiretroviral therapy treated with liraglutide

      ea0085p40
  • Pituitary and Growth 1
  • • Use of the U.K. 100,000 genomes project to identify the genetic basis of childhood pituitary disorders within a tertiary paediatric endocrinology centre

      ea0085p41
    • The endocrine phenotype of SWI/SNF-associated coffin-siris syndrome includes pituitary endocrinopathies, pituitary hypoplasia, and septo-optic dysplasia

      ea0085p42
    • Neurobehavioural impairments in children with septo-optic dysplasia: a scoping review

      ea0085p43
    • Understanding the molecular basis of short stature in six patients with pathogenic variants in HMGA2

      ea0085p44
    • The use of 6-monthly GnRH analogues in the paediatric population

      ea0085p45
    • A rare heterozygous IGFI variant impairing IGF-I cleavage and causing postnatal growth failure: a novel disease mechanism offering insights into IGF-I physiology

      ea0085p46
  • Adrenal 2
  • • Salivary sampling in neonates, infants, and young children: glucocorticoid stability under different conditions and the introduction of a novel collection technique

      ea0085p47
    • Phenotypic variability in X-linked adrenoleukodystrophy

      ea0085p48
    • Effect of high-dose maternal steroids on neonatal adrenal function

      ea0085p49
    • Safety alerts for patients at high risk of acute adrenal insufficiency

      ea0085p50
    • Paediatric adrenocortical carcinoma presents with virilization and glucocorticoid deficiency - a rare presentation

      ea0085p51
  • Diabetes 2
  • • Review of glycaemic control following change from standardised insulin pump to hybrid closed loop

      ea0085p52
    • Diabetic ketoacidosis in children and young people (CYP) at diagnosis across Wales during the COVID-19 pandemic: have the quality improvement (QI) innovations made an impact?

      ea0085p53
    • Technology alone is not the answer for closing the deprivation gap in Type 1 Diabetes Mellitus (T1DM)

      ea0085p54
    • Recognising and raising safeguarding and child protection issues in childrens diabetes. Early findings from a qualitative study exploring specialist paediatric diabetes healthcare professionals' experiences

      ea0085p55
    • Improving early diagnosis of type 1 diabetes (T1D) during the COVID-19 pandemic

      ea0085p56
    • Compliance with screening and monitoring guidelines for macrovascular cardiovascular disease in children and young people with diabetes

      ea0085p57
    • COVID-19 and newly diagnosed type1 diabetes mellitus in paediatrics

      ea0085p58
    • An alternative case of diabetes

      ea0085p59
    • A case of possible diabetes in remission in a 15 year old girl with significant deliberate weight loss

      ea0085p60
  • Diabetes 3
  • • GAME-SET-MATCH mnemonic: an infographic to teach effective dynamic glucose management strategies improving time in range in children with type 1 diabetes using continuous glucose monitoring

      ea0085p61
    • Recognition and management of hypertension in children and young people with diabetes

      ea0085p62
    • Audit of the use of HbA1c in children and young people without a prior diagnosis of diabetes mellitus

      ea0085p63
    • Protocol for a feasibility study and process evaluation of a psychosocially modelled diabetes education programme for young people with type 1 diabetes: the yes study

      ea0085p64
    • Use of artificial pancreas systems in routine clinical care is effective in improving glycaemic control in paediatric patients

      ea0085p65
    • Simplified diabetes education for parents with poor health literacy

      ea0085p66
    • Prolonged honeymoon phase in 2 paediatric cases with type 1 diabetes mellitus

      ea0085p67
    • Insulin adjustment for local cultural event (summer marching season)

      ea0085p68
  • Miscellaneous 2
  • • An evaluation of the experiences with services in wales for children and young people and their families with prader willi syndrome (PWS)

      ea0085p69
    • Osteoma cutis and medulloblastoma due to heterozygous inactivating GNAS mutation - a rare association due to reduced GNAS expression in tissues

      ea0085p70
    • Evaluation of a new multidisciplinary clinic for the endocrine assessment of patients with duchenne muscular dystrophy

      ea0085p71
    • Evaluation of an educational intervention on puberty/pubertal induction in adolescent girls with turner syndrome

      ea0085p72
    • Central precocious puberty in a patient with short stature and skeletal abnormalities in KBG syndrome due to ANKRD11 variant

      ea0085p73
    • Management challenges in a patient with APECED due to endocrine and nonendocrine multisystem involvement

      ea0085p74
    • Three different presentations of a rare monogenetic cause of hypoparathyroidism in a small district general hospital

      ea0085p75
  • Obesity 2
  • • Semaglutide as a safe and effective weight loss treatment in children with obesity

      ea0085p76
    • Incidence and predictors of the complications of childhood obesity

      ea0085p77
    • Evaluating glycaemic variations in children and young people with obesity using continuous glucose monitoring

      ea0085p78
    • Baseline health-related quality of life in UK children and adolescents with severe obesity

      ea0085p79
    • The use of GLP-1 agonist in an adolescent with type 1 diabetes mellitus and obesity

      ea0085p80
  • Pituitary and Growth 2
  • • A novel IGF1R variant in a child with mild IGF1 resistance, normal birth weight, mild short stature and microcephaly

      ea0085p81
    • Glucagon tolerance tests in a tertiary paediatric centre: an evidence-base for protocol refinement

      ea0085p82
    • DNA haplotypes influencing the response to growth hormone therapy are disproportionately inherited from neanderthals

      ea0085p83
    • Panyiatopoulous syndrome in the setting of precocious puberty

      ea0085p84
    • Abstract unavailable

      ea0085p85
  • Thyroid
  • • Congenital hypothyroidism: should radioisotope scanning be made mandatory to improve etiological diagnosis?

      ea0085p86
    • Congenital hypothyroidism due to PAX8 gene mutation - a case report

      ea0085p87
    • Hypothyroidism - unknown through the known

      ea0085p88
    • An unusual case of encephalopathy

      ea0085p89
    • 2 cases of thyroid hormone resistance

      ea0085p90
    • A tale of twin thyroids - a report of identical twins with pten hamartoma syndrome, developing different thyroid tumours in early adolescence

      ea0085p91
    • Multisystem involvement in severe primary hypothyroidism

      ea0085p92
    • Thyroid hormone resistance from misdiagnosis to successful pregnancy

      ea0085p93
    • Don't make a drama out of a Crisis!

      ea0085p94