Endocrine Abstracts

Young people with Type 1 Diabetes Mellitus (T1DM) can achieve improved glycaemic control by using technology. T1DM technology is steadily improving however access to it remains variable across the UK. Those from ethnic minorities and deprived areas are less likely to access technology and more susceptible to developing complications of diabetes. Understanding the reasons for health inequalities is essential to facilitate use of available technology.Aim: ...

Introduction: Diabetic Ketoacidosis (DKA) is a potentially life threatening complication of type-1 diabetes mellitus (T1DM) in children and young people (CYP). An Integrated Care Pathway (ICP) for management of DKA is based on the current British Society for Paediatric Endocrinology and Diabetes (BSPED) guidelines. The BSPED guideline moved away from cautious fluid replacement toward a liberal approach for resuscitation and maintenance fluids based on current evidence. The ICP...

Background: Down Syndrome (DS) is the commonest form of chromosomal trisomy. Genetic factors in DS may increase the risk for diabetes. Obesity and type 2 diabetes mellitus (T2DM) rates have increased in the general populationbut it is not known whether this similarly affected people with DS.Objective: To determine whether DS is associated with increased incidence of diabetes and the relationship with obesity across the lifespan compared to controls.<...

Introduction: NICE Guidance 18 updated in March 2022 will make real-time continuous glucose monitoring (rtCGM) the standard of care and recommends the cheapest rtCGM that meets an individual’s needs. Eight rt-CGM devices have Conformité Européene (CE) mark for paediatrics with type 1 diabetes. There are no published performance standards for CE mark; however, the Food & Drug Administration (FDA) published their interoperable CGM (iCGM) criterion. For iCGM ap...

Introduction: Pregnancy under the age of 19 is considered high-risk1; and a pregnancy with diabetes at this age further increases that risk2,3. With the correct advice and counselling, these risks can be greatly reduced. Here we describe a strategy to raise awareness by addressing this as part of regular clinic visits.Method: Prior knowledge of potential complications of pregnancy was assessed as part of a clinical consultation. Evi...

In June 2021, NHS England commissioned 15 Complications from Excess Weight (CEW) services to pilot Tier 3 paediatric weight management services in England. This study aimed to assess initial patient experiences / responses to weight management strategies delivered in a single CEW service between January-June 2022.Methodology: We conducted an online survey to assess patient experiences, motivators and barriers to healthy lifestyle change in 45 patients se...

Background: Liraglutide is a glucagon-like peptide analogue recently approved for use in children and young people for treating obesity. It is recommended for use within multidisciplinary weight management services, alongside dietetic and lifestyle interventions, in children over 12 years with severe obesity.Aim: To describe our experiences of using liraglutide in a tier 3 paediatric obesity service in a patient cohort who had previously failed to succes...

Background: In 2019, funding for continuous glucose monitoring (CGM) commenced for children and young people with diabetes (CYPD) in our region. However, there was no local established CGM structured education programme. We developed ‘the CGM Academy’ with continuous improvement using the Plan-Do-Study-Act (PDSA) cycle.Objectives: To review the PDSA cycle of improvements to deliver structured education using CGM.Methods: ...