Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology BES 2021

Edinburgh, United Kingdom
08 Nov 2021 - 10 Nov 2021

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Join us in Edinburgh for the flagship event of the Society for Endocrinology

Symposia

Characterising the cortex to improve clinical care

ea0077s6.1 | Characterising the cortex to improve clinical care | SFEBES2021

Characterizing the Cortex to Improve Clinical Care. Single cell sequencing: lessons for the pathogenesis of adrenocortical tumours

Ronchi Cristina L

Key learning points• Adrenocortical tumors comprise frequent benign adenomas and rare aggressive carcinomas (ACC).• cAMP/PKA pathway plays a central role in the pathogenesis of cortisol-producing adenomas - associated with Cushing syndrome, while molecular alterations in Wnt/β-catenin, Rb/p53 pathway and chromatin remodeling are frequent in ACCs.<p class="a...