Endocrine Abstracts

Contents

• Society for Endocrinology BES 2021
• • Plenary Lectures
  • British Thyroid Association Pitt-Rivers Lecture
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  • Society for Endocrinology Starling Medal Lecture
  • • Strategies to turn up the heat - investigating human brown adipose tissue function

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  • Society for Endocrinology Dale Medal Lecture
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  • Society for Endocrinology Transatlantic Medal Lecture
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  • Society for Endocrinology International Medal Lecture
  • • Activation of the gp130 receptor: a panacea for the treatment of metabolic diseases?

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  • Society for Endocrinology European Medal Lecture
  • • Rethinking critical illness-related corticosteroid insufficiency

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  • Clinical Endocrinology Trust Lecture
  • • The yin and yang of hormones and glucose

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  • Clinical Endocrinology Trust Visiting Professor Lecture
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  • Society for Endocrinology Medal Lecture
  • • Revisiting Cushing’s: The power of pre-receptor metabolism

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  • Society for Endocrinology Jubilee Medal Lecture
  • • Cancer treatment endocrinopathies and growth hormone status throughout life

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• Debate: To block or not to block
• • Controversies in peri-operative management of catecholamine-producing tumours
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    • Abstract unavailable

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• Society for Endocrinology Journal Awards
• • Society for Endocrinology Journal Award – Journal of Endocrinology
  • • Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish

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  • Society for Endocrinology Journal Award – Journal of Molecular Endocrinology
  • • STAT5 ablation in AgRP neurons increases female adiposity and blunts food restriction adaptations

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  • Society for Endocrinology Journal Award – Endocrine-Related Cancer
  • • LDLR-mediated lipidome-transcriptome reprogramming in cisplatin insensitivity

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  • Society for Endocrinology Journal Award – Endocrine Connections
  • • Role of fasting duration and weekday in incretin and glucose regulation

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  • Society for Endocrinology Journal Award – Clinical Endocrinology
  • • Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population

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• Awards and Prizes
• • Teaching Achievement Award
  • • Developing a Career in Education

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  • Outstanding Clinical Practioner Award
  • • Outstanding Clinical Practitioner Award: Improving the care of patients with thyroid diseases

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    • Outstanding Clinical Practitioner Award 2021

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  • Nikki Kieffer Medal
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  • Endocrine Nurse Award
  • • Abstract unavailable

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• Early Careers and Plenary Orals
• • Early Career Prize Lecture Basic Science
  • • Gene discovery in neonatal diabetes to uncover the mechanisms regulating human pancreas development

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  • Early Career Prize Lecture Basic Science (1)
  • • Cardiometabolic disease burden and urine steroid metabolome in benign adrenocortical tumours: a case-control study

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  • Clinical Endocrinology Trust Best Abstract Clinical
  • • Phase 3 and extension study of modified-release hydrocortisone in the treatment of congenital adrenal hyperplasia

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  • Clinical Endocrinology Trust Best Abstract Basic
  • • The vagal Calcium Sensing Receptor mediates the effect of protein ingestion on insulin release and regulates macronutrient metabolism

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• Symposia
• • Lifestyle hacks for metabolic disease
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  • Nuclear receptors in male reproduction
  • • Liver X Receptors (LXR)s and testicular function

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    • Bile acid metabolism and nuclear receptors in male reproduction

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    • Abstract unavailable

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  • Novel approaches to the diagnosis and treatment of endocrine neoplasia
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  • Understanding pathogenesis: development of novel treatments
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    • Thyroid eye disease

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    • Translational studies in thyroid hormone transport

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  • What is new in calcium and bone
  • • Osteomorphs: a new cell entity regulating bone resorption

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  • Characterising the cortex to improve clinical care
  • • Characterizing the Cortex to Improve Clinical Care. Single cell sequencing: lessons for the pathogenesis of adrenocortical tumours

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• What is New?
• • (1)
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• Clinical Management Workshops
• • Pituitary challenges: Prompt, practical and post-op
  • • Apoplexy

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    • Abstract unavailable

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    • Post operative management of pituitary patients - Keeping it straightforward and safe

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  • Widening perspective on reproductive health
  • • Endometrial health - the role of the specialist menstrual disorders service

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• Basic Physiology Workshops
• • New techniques and approaches
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  • Model systems
  • • Modelling diabetes using iPSCs and adult derived organoids

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• How Do I? Sessions
• • How do I. . .? 1
  • • Dr Claire Higham

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    • How do I investigate a young person with a low trauma fracture?

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    • How do I optimise thyroid status after RAI therapy?

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  • How do I. . .? 2
  • • How do I investigate abnormal alkaline phosphatase?

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    • A low testosterone level in a man with obesity - what to advise based on current evidence

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    • How do I manage pituitary macroadenoma in pregnancy?

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    • How do I confirm biochemical diagnosis of primary aldosteronism?

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• Meet The Expert Sessions
• • Adrenal and Cardiovascular
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  • Bone and Calcium
  • • Bone turnover markers in the management of osteoporosis

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  • Thyroid
  • • Meet the Expert (Thyroid): Thyroid Disease Assessment and Management; controversies in the NICE Guidelines.

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  • Endocrine Cancer and Late Effects
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  • Reproductive and Neuroendocrinology
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  • Metabolism, Obesity and Diabetes
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  • Nurse
  • • Abstract unavailable

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• Clinical Skills
• • Genetics for the endocrinologist
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• Basic Skills
• • Grants and teaching
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    • How to make meaningful improvements to your teaching with common and accessible technologies

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• Early Careers Session
• • Broadening your Career Pathway - What else can you do with your skills?
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    • Research Facilitation or Management

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    • Influencing at scale: NHS leadership and shaping policy

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    • Clinical Teaching Careers

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    • Abstract unavailable

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• Nurse Sessions
• • Acromegaly
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    • Biochemical cure - is this enough?

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    • Addressing the unmet psychosocial needs of patients with treated Acromegaly

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  • The past, present and future of endocrinology within a District General Hospital (DGH)
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  • Management of endocrine conditions in the time of COVID
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• Future Of Endocrinology Post Covid-19 Update
• • (1)
  • • Abstract unavailable

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• Cutting Edge Session
• • Use and abuse endocrinology - enhancing performance at any cost?
  • • Abstract unavailable

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    • GH as a performance enhancing drug

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    • Abstract unavailable

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• Senior Endocrinologists’ Session
• • (1)
  • • Are gonadotrophins more than gonadotrophins?

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    • Abstract unavailable

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    • INSL3: a new index of testis function in puberty and aging

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• Oral Communications
• • Reproductive and Neuroendocrinology
  • • Melanocortin-4 receptor agonism improves sexual brain processing in women with low sexual desire

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    • Hyper-phosphorylation of [beta]-catenin at Serine552 correlates with invasion and predicts recurrence of Non-Functioning Pituitary Tumours (NFPTs)

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    • Acromegalic cardiomyopathy in pituitary-specific aryl hydrocarbon receptor interacting protein (Aip) gene knockout animals

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    • Intranasal Kisspeptin Administration Stimulates Reproductive Hormone Secretion in Healthy Men

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    • Is radiotherapy for pituitary adenoma or craniopharyngioma associated with increased risk of second brain tumour? A long-term multi-centre study of 3,679 patients

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    • Differential follicle stimulating hormone glycosylation modulates pre-antral follicle growth and survival rates

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  • Endocrine Cancer and Late Effects
  • • Outcomes of surgery and treatment with selective RET TK inhibitor Selpercatinib in children with MEN2 and advanced MTC.

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    • An emerging role for proteostasis modulators targeting NIS activity to enhance radioiodide therapy in thyroid cancer

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    • A novel in vivo platform for studying tumour vascularization and endocrine responses

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    • PBF phosphorylation regulates cell motility of thyroid and breast cancer cells

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    • A novel MiR-346-Directed DNA damage mechanism is regulated by its interaction with long non-coding RNA, NORAD, in prostate cancer

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    • Transcriptomic analysis of succinate dehydrogenase subunit deleted cells to identify molecular mechanisms underlying the increased metastatic potential of SDHB-deficient tumours

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  • Metabolism, Obesity and Diabetes
  • • The serotonin transporter SLC6A4 protects human brown adipose tissue from serotonin-mediated suppression of thermogenesis.

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    • Comparing the transcriptional landscape between lean and obese mice within the small intestinal segments

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    • Sex-specific risk of obesity and cardiometabolic disease in low- and middle-income countries (LMICs): a meta-analysis in 681929 individuals

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    • Hepatic choline deficiency underpins amelioration of visceral obesity and diabetes in ectonucleotide pyrophosphatase (Enpp)-6^-/- mice

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    • Microbial tryptophan metabolites modulate L-cell induced GLP-1 secretion to improve glucose homeostasis

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    • Stimulation of motilin secretion by bile, free fatty acids and acidification in human duodenal organoids

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  • Adrenal and Cardiovascular
  • • Development of [18F]AldoView as the first highly selective aldosterone synthase PET tracer for imaging of patients with Primary Hyperaldosteronism.

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    • Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause.

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    • [¹¹C]Metomidate PET/CT can aid decision-making in patients with primary aldosteronism

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    • 24-hour dynamics of free tissue adrenal hormones: A description of healthy normal variation

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    • Circulating cell-free DNA-based biomarkers as a tool for disease surveillance in adrenocortical carcinoma

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    • Glucocorticoids and the Vascular Molecular Clock: Implications in Vascular Function Control

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  • Bone and Calcium
  • • Successful adeno-associated virus mediated neonatal gene therapy treatment of hypophosphatasia murine model resulted in bone maturation and increased survival to at least 18 months

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    • Gastric inhibitory polypeptide (GIP) reduces human osteoclast activity by suppressing multiple signalling pathways

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    • Role of Intact and C-Terminal FGF-23 Assays in the Investigation of Metabolic Bone Disease.

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    • Nuclear factor I/X (NFIX) regulates the transcriptional activity of the cellular retinoic acid binding protein 2 (CRABP2) promoter and alters CRABP2 expression in Marshall-Smith Syndrome (MSS) patients.

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    • Diacylglycerol kinase delta haploinsufficiency in mice causes hypocalcaemia: relevance to human Autosomal Dominant Hypoclacemia (ADH)

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    • The role of vitamin D supplementation in critically ill patients with COVID-19

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  • Thyroid
  • • Adjuvant Rituximab - exploratory trial in young people with Graves’ disease

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    • Concerted action of TH transporters MCT8 and OATP1C1 regulates adult hippocampal neurogenesis and hippocampal function in mice

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    • Failure of Radioiodine Remnant Ablation to Improve Postoperative Outcome in 2668 Adult Patients with AJCC/pTNM Stage I Papillary Thyroid Carcinoma

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    • AP-2 and Moesin Regulate the Internalisation of the Sodium-Iodide Symporter and Affect I¹²⁵ Uptake in Thyroid Cancer Cells.

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    • Effects of in utero thyroid hormone exposure on human neurodevelopment: MRI analysis from the Controlled Antenatal Thyroid Screening Study

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    • Forty years' experience of national screening programme for congenital hypothyroidism in Northern Ireland.

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• Oral Poster Presentations
• • Thyroid
  • • Factors predicting long-term outcome and the need for surgery in Graves Orbitopathy extended follow-up from the CIRTED Trial

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    • Long term Management of Thyrotoxicosis with Anti thyroid Drugs (ATDs)

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    • Thyroid Endocrine Nurse Service: Improving patient experience

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    • Autoimmune thyrotoxicosis: Is first line treatment with anti-thyroid medication good enough?

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  • Adrenal and Cardiovascular
  • • A phase 1 clinical trial evaluating the safety and efficacy of up to two administrations of the adrenal PET tracer [¹⁸F]CETO in healthy volunteers and patients with primary aldosteronism

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    • Single-centre analysis of 900 short synacthen tests: do pre-test clinical or biochemical variables predict failure?

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    • PLK1 inhibitors as a new targeted treatment for adrenocortical carcinoma

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    • Modelling changes in the control, secretion and metabolism of cortisol during and after heart surgery

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  • Reproductive and Neuroendocrinology
  • • Discordant growth hormone and insulin like growth factor-1 values are associated with an increased mortality over concordant normal values in patients treated for acromegaly

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    • An ex-vivo human placental model demonstrates that temporal fluctuations in maternal glucose in gestational diabetes alter placental transcriptome networks associated vascular development and angiogenesis

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    • ’Suppression imaging’ - a novel PET technique for increasing confidence in the localisation of secretory pituitary microadenomas

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    • Stem cell heterogeneity and regulation in the postnatal pituitary gland

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  • Metabolism, Obesity and Diabetes
  • • Investigating the role of the gut metabolome in appetite and obesity

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    • 3 mg Liraglutide ameliorates inflammation and improves hypothalamic regulation of energy homeostasis by modulation of Sphingosine-1-Phosphate signalling in super-responders

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    • The Chemerin-CMKLR1 Axis is Functionally Important for Central Regulation of Energy Homeostasis

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    • Audit of Clinical Outcomes with Dexamethasone in Patients Hospitalised with COVID-19

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  • Bone and Calcium
  • • Parathyroid hormone (PTH) of 1.6 pmol/l or more at 6 months is associated with delayed recovery of parathyroid function in post-surgical hypoparathyroidism (PoSH)

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    • Society for Endocrinology / Parathyroid UK National Hypoparathyroidism Management Audit

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    • Vitamin D deficiency is highly prevalent among patients who died from COVID-19 in the North-East of England.

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    • Normocalcaemic hyperparathyroidism: Impact of assay and reference range differences on the diagnosis

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  • Endocrine Cancer and Late Effects
  • • Incidental findings are common, but rarely clinically significant, in patients with Neuroendocrine Tumours undergoing Gallium68 Dotatate PET CT; results from a one year retrospective review

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    • The evaluation of a musculoskeletal health package intervention to prevent bone toxicity in women with gynaecological malignancies undergoing pelvic radiotherapy. The RadBone randomised controlled feasibility study

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    • An unusual presentation of hypoglycaemia: An investigative challenge

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    • Virtual Blood Pressure Monitoring in the Pre-operative Management of Phaeochromocytoma Patients in a Tertiary Centre during the COVID-19 Pandemic

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• Featured Clinical Case Posters
• • (1)
  • • Cinacalcet in the Treatment of Malignancy-Related Hypercalcaemia: A Case Report

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    • Familial hypocalciuric hypercalcaemia (FHH) type 3: A rare cause of parathyroid (PTH) dependent hypercalcaemia with associated learning disabilities and behavioural problems

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    • Hypercalcemia caused by Advanced Chronic liver disease without Malignancy: A rare entity

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    • Kennedy’s Disease: An uncommon cause of androgen insensitivity and motor neuropathy

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    • Transformation of a non-functional to a functional neuroendocrine tumour

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    • Monozygotic twins with hypothyroidism responding to T3/T4 combination: a role for Nuclear Factor-kappa B (NF-κB)?

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    • COVID-19 AstraZeneca Vaccination Induced Subacute Thyroiditis

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    • Atraumatic chylothorax due to Graves’ disease

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    • A Puzzling Set of Thyroid Function Tests: Thyroid storm or Secondary Hypothyroidism?

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    • Alemtuzumab mediated alternating states of thyroid dysfunction

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• Poster Presentations
• • Adrenal and Cardiovascular
  • • Plasma steroid profiles in patients hospitalised with COVID-19 - an ISARIC/WHO CCP-UK cohort study

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    • A QIP to improve quality of care in adrenal insufficiency and steroid dependent patients

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    • Improving outcomes from SSTS: Redefining Cortisol Cut-Offs

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    • The saline infusion test, but not the captopril challenge test, is associated with intra-test hypertension and hypokalaemia in patients being investigated for primary aldosteronism

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    • SIMBA as a complement to small group teaching in undergraduate medical curriculum: A pilot study

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    • The effect of plasma potassium on hospital length of stay in unselected acute admissions

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    • Simulation via Instant Messaging - Birmingham Advance (SIMBA): Impact of online simulation-based learning on doctors’ confidence in managing cases during the COVID-19 pandemic

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    • Comparative steroid profiling in large animals

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    • Cortisol measurement post steroids (Dexamethasone) treatment for COVID-19

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    • Method of venesection and location of peripheral sample alter adrenal venous sampling results and interpretation in primary aldosteronism

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    • SGPL1 regulates expression of electron transport chain components to modulate cellular metabolism in the adrenal gland

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    • A crisis waiting to happen; long-term steroid use in a cohort of neuromuscular patients - what do they know?

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    • Bilateral Adrenal Haemorrhage due to vaccine induced thrombosis and thrombocytopaenia following Covid-19 Vaccine

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    • COVID-19 and Adrenal Insufficiency: A retrospective Study at a District General Hospital

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    • Giant bilateral adrenal mylelolipoma in a patient with congenital adrenal hyperplasia

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    • Implications of UK adrenalectomy guidelines for remote and rural patients in the Highlands of Scotland: An audit of adrenalectomy practice in a single UK Centre

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    • The 4E (Engage, Educate, Equip and Empower): A framework for supporting the approach in the prevention, early recognition and effective management of adrenal crisis in adults

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    • Do we need to reset the threshold of screening for Autonomous Cortisol Secretion?

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    • Prednisolone versus Hydrocortisone in Adrenal Insufficiency: A positive and negative control cross-sectional study

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    • Adrenal Incidentaloma Pathway - A four-year experience at a teaching hospital

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    • A review of management of adrenal incidentalomas at a District General Hospital and development of a local clinical management pathway

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    • Searching for a new PAL

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    • Feminizing adrenal tumours (FAT): Rare tumours of the adrenal gland

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    • In vitro splicing assay proves the pathogenicity of intronic variants in MRAP

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    • Undetectably low blood aldosterone concentrations are prevalent in COVID-19 patients but poorly quantified by chemiluminescent immunoassay

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    • Glucocorticoid receptor activation regulates cardiomyocyte cell cycle in neonates

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    • Classic and 11-oxygenated androgens in serum and saliva across adulthood and the menstrual cycle - a mass spectrometry-based cross-sectional study

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    • Impact of COVID-19 on patients with primary adrenal insufficiency: a cross-sectional study

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    • The ULTRADIAN consortium - Ambulatory in vivo micro dialysis in primary adrenal insufficiency, preliminary data

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    • Should the 1 mg -overnight dexamethasone suppression test be repeated in patients with benign adrenal incidentalomas and no overt hormone excess?

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    • Auditing Adrenal Vein Sampling for Primary Aldosteronism to highlight existing challenges

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    • Clinical prediction scores in primary aldosteronism reliably identify a subset of patients with bilateral disease avoiding the need for adrenal venous sampling

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    • An unusual presentation of bilateral adrenal haemorrhage/infarction and adrenal insufficiency associated with Astrazeneca COVID-19 vaccine

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    • An analysis of full blood count parameters in a cohort of patients with classical congenital adrenal hyperplasia

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    • A case of immunoglobulin interference in an Adrenocorticotropic hormone immunoassay

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    • Co-syntropin stimulation test (CST) usage for the assessment of adrenal insufficiency (AI) - is less more?

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    • Autonomous cortisol secretion (ACS) in other overt functioning adrenal adenoma: two case reports

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    • Service Evaluation of Cortisol Testing for Adrenal Insufficiency in NHS GG&C Clyde Sector

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    • Atheromatous unilateral renal artery stenosis presenting as pheochromocytoma mimic

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    • Crescendo renal failure: an unusual presentation of Addison’s disease

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    • Iatrogenic Cushing’s syndrome due to betamethasone nasal drops

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    • The diagnostic and management conundrum of an unusual case of hypertension in pregnancy

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    • Successful spontaneous pregnancy after transphenoidal surgery and bilateral adrenalectomy for Cushing’s disease: A case report

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    • Retrospective analysis of the screening for primary hyperaldosteronism (PHA) - are we doing enough beyond screening?

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    • Adrenal insufficiency secondary to primary adrenal lymphoma

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  • Bone and Calcium
  • • Hyperparathyroid service evaluation at the Royal Cornwall Hospital Trust from 2013 to 2021

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    • Seasonal variations in circulating vitamin D appear gender dependent and may highlight a novel health inequality

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    • Pre-antiresorptive therapy dental screening (PADS): a successful intervention against medication related osteonecrosis of the jaws (MRONJ)

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    • An Audit into the Diagnosis and management of primary hyperparathyroidism

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    • Case Report: Asymptomatic hypercalcaemia in a patient with TB re-activation

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    • Comparison of local cinacalcet prescribing trends with NICE guidelines

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    • Pregnancy and Lactation Associated Osteoporosis (PLO)- Case Report

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    • Recombinant PTH 1-84 (Natpar) treatment in a case of refractory hypocalcaemia secondary to surgical hypoparathyroidism and malabsorption post-gastric bypass

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    • Bendroflumethiazide-induced hypocalciuria in a patient with hypercalcaemia and unsuppressed parathyroid hormone levels

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    • Severe Hypercalcemia in a Patient with Milk Alkali Syndrome

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    • Vitamin D deficiency and inflammation in IBD patients

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    • Primary Cinacalcet therapy is safe and effective as alternative or bridging modality in Primary Hyperparathyroidism

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    • A case of familial hyperparathyroidism with an uncommon mutation

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    • Immobilization induced hypercalcemia

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    • Hypercalcaemia as an isolated manifestation of Sarcoid Myositis: A rare case report

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    • An interesting case of Turner syndrome and Parathyroid Carcinoma with recurrent mild asymptomatic hypercalcemia

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    • Autoimmune Polyglandular syndrome presenting with multiple Endocrinopathies

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    • Undiagnosed probable genetic primary hyperparathyroidism presenting with brown tumors and deafness

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    • Symptomatic primary hyperparathyroidism in the first trimester of unplanned pregnancy

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    • Resolution of primary hyperparathyroidism following parathyroid adenoma infarction on treatment with cinacalcet

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    • Hypercalcemia secondary to Hypervitaminosis D caused by over the counter consumption of vitamin D

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    • Systematic review of cardiovascular morbidity and mortality associated with primary hyperparathyroidism; does early surgical intervention improve the outcome?

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  • Endocrine Cancer and Late Effects
  • • A Case of MEN-1 Syndrome presenting as Lung carcinoid tumour

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    • The Impact of COVID-19 on Endocrine Treatments from a Neuroendocrine (NET) patient perspective: homecare and self-injection

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    • Parathyroid Tumour of Uncertain Malignant Potential (PTUMP): a rare case of hyperparathyroidism associated with transient hyperglycaemia

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    • A challenging case of hyponatraemia

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    • Novel management of resistant hypoglycaemia in a patient with malignant Insulinoma

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    • A case report of Parathyroid Carcinoma following a low-impact trauma

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    • Simultaneous ADH and ACTH secretion by small cell lung cancer: a diagnostic challenge

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    • Pituitary metastasis from lung adenocarcinoma presenting with panhypopituitarism

      ea0077p170
  • Metabolism, Obesity and Diabetes
  • • Longitudinal clinical trajectory analysis of individuals before and after diagnosis of Type 2 Diabetes Mellitus (T2DM) indicates that vascular problems and asthma pre-date diabetes diagnosis by many years

      ea0077p39
    • A randomised controlled pilot trial of oral 11[beta]-HSD1 inhibitor AZD4017 for wound healing in adults with type 2 diabetes mellitus

      ea0077p40
    • Investigating 2-oleoylglycerol responsive neuronal pathways

      ea0077p41
    • Chronic inflammation regulates androgen metabolism and exposure in Macrophages

      ea0077p42
    • 5[beta]-reductase is downregulated in patients with non-alcoholic fatty liver disease and hepatocellular carcinoma and controls metabolic and proliferative phenotype through LXR-dependent mechanisms

      ea0077p43
    • 11[beta]-HSD1 determines the extent of muscle atrophy during an acute exacerbation of COPD

      ea0077p44
    • PARP1 mediated ADP-Ribosylation events during myoblast fusion contribute to murine skeletal muscle phenotype

      ea0077p45
    • AKR1C1 knock-down does not alter cell proliferation or response to chemotherapeutic agents in human hepatoma models

      ea0077p46
    • Leicestershire wide steroid safety programme 2019-21 and effectiveness of electronic alert on prescription software in a tertiary centre

      ea0077p47
    • The neuroophthalmological manifestations of obesity

      ea0077p48
    • Interplay of NUCB2/Nesfatin-1 and inflammation in white adipose tissue

      ea0077p49
    • Lipocalin 2, a mediator or marker of adipocyte dysfunction?

      ea0077p50
    • Can modulation of beta cell ER stress in the KINGS (Ins2^+/G32S) mouse abolish sex differences in diabetic phenotype?

      ea0077p51
    • How would school children design a poster about diabetes, obesity, health technologies and emotional wellbeing awareness?

      ea0077p52
    • DKA registry: Creating a single data collection system for DKA in the West Midlands has helped identify best practices across hospitals

      ea0077p53
    • Central adiposity and diabetes are causally associated with kidney stone disease

      ea0077p54
    • A novel approach to serum multi-steroid profiling using ultra high-performance liquid chromatography-tandem mass spectrometry with post column infusion ammonium fluoride

      ea0077p55
    • Novel regulation of GR mediated gene expression by PARP-1 in mouse skeletal muscle cells

      ea0077p56
    • Transcriptomic profiling of human enteroendocrine cells in primary ileal and duodenal organoid culture

      ea0077p57
    • Outcomes of postmenopausal women with non-alcoholic fatty liver disease (NAFLD)

      ea0077p58
    • Acidosis reduces 11[beta]-HSD1 activity in human primary muscle cell cultures

      ea0077p59
    • Mimicking chronic hyperglycaemic conditions in primary human endothelial cell cultures using pathophysiological concentrations of glucose in prediabetes and type 2 diabetes

      ea0077p60
    • The Effect of Bariatric Surgery on the proteome of people achieving remission of Type 2 Diabetes

      ea0077p61
    • Hypoglycaemia in non-diabetics. An Endocrinologist’s perspective

      ea0077p62
    • Polygenic lipid risk as a precipitant in Type III hyperlipidaemia

      ea0077p63
    • The Variability In Glycosylated Haemoglobin (HbA1c) Testing Interval In People With Diabetes Is Linked To Long-Term Diabetes Control, Independent of HbA1c Test Interval

      ea0077p64
    • Meeting the Challenge of Bariatric Surgery during the first wave of Covid -19 in a patient with a BMI >100kg/m²

      ea0077p65
    • Challenges in the management of severe hypertriglycridaemia causing acute pancreatitis

      ea0077p66
    • Association of Vitamin D and Adiposity in Children and Adolescents with type 1 diabetes: a case-control study

      ea0077p67
    • Rhino-orbital-cerebral mucormycosis in diabetes patients with COVID-19

      ea0077p68
    • Persistent Lactic Acidosis after resolution of DKA in Young Patients with Poorly Controlled Diabetes Mellitus

      ea0077p69
    • Real-world metabolic outcomes of semaglutide use in patients with type 2 diabetes: a retrospective study from a single centre in the United Arab Emirates

      ea0077p70
    • Lipopolysaccharide signalling modulates brown fat transcriptome and cytokine secretion

      ea0077p71
    • Impact of PCSK9 Inhibitors on hypercholesterolaemic patients at a tertiary centre lipid clinic

      ea0077p72
    • Beer Potomania Hyponatraemia: a discordant medley of symptoms of osmotic demyelination syndrome with ataxia and dysarthria

      ea0077p73
    • Long-term follow-up of hemichorea-ballism syndrome associated with acute hyperglycemic crisis

      ea0077p74
    • [ldquo]The eyes have it[rdquo]: a case of treatment-induced neuropathy of diabetes

      ea0077p75
    • Anaemia among patients with type 2 diabetes mellitus in Kano, Northwestern Nigeria

      ea0077p76
    • Relationship Between [beta]-cell Function and Proteinuria in a Cohort of Type 2 DM Patients at OAUTHC Ile-Ife, Nigeria

      ea0077p77
    • The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

      ea0077p171
    • ATP-Binding Cassette Subfamily C Member 1 (ABCC1) influences adiposity, glucose homeostasis and insulin sensitivity

      ea0077p172
    • Associations between reduction in body mass index (BMI) and proteins linked to neural function after 12 months of bariatric surgery

      ea0077p173
    • Vitamin D status in horses and its association with adiposity

      ea0077p174
    • Pressure from pericytes: angiotensin II induced neuropathic pain development as a complication of hypertension

      ea0077p175
    • Asprosin impact on mitochondrial metabolism in obese adipose tissue, a tale of two depots?

      ea0077p176
    • Obesity-induced upregulation of chemokine Ccl4 in mouse visceral adipose tissue: effects on [beta]-cell function

      ea0077p177
    • Abstract unavailable

      ea0077p178
    • Impact of [alpha]-MSH on glucose tolerance in healthy participants: The first in human randomized, double-blind, placebo-controlled, physiological study

      ea0077p179
    • Neurotensin improves glucose tolerance via activation of peripheral NTSR1-expressing neurons

      ea0077p180
    • Bio informatic Analysis Reveals Hundreds of Differentially-Expressed lncRNAs with Potential Roles in [beta]-Cell Proliferation

      ea0077p181
    • Rat primary hypothalamic, but not cortical, astrocytes increase use of glutamate to fuel metabolism after recurrent low glucose

      ea0077p182
    • The influence of metabolic states and a high fat meal on circulating chemerin

      ea0077p183
    • Does human serum impact differentiation and mitochondrial function of human LHCN-M2 skeletal muscle cells?

      ea0077p184
    • Measurements of skin temperature in lean and obese humans at thermoneutrality and following cold exposure

      ea0077p185
    • Predictors of adverse outcomes in COVID-19: A retrospective cohort study comparing the first two waves of COVID-19 hospital admissions in London, with a focus on diabetes

      ea0077p186
    • Asprosin induces acute pro-inflammatory effects on THP-1 macrophages

      ea0077p187
    • Exploring the translational potential of the NPY Y4 receptor for treating Type 1 Diabetes

      ea0077p188
    • BMI category-specific waist circumference thresholds for predicting the risk of cardiometabolic diseases: A nationwide population-based study

      ea0077p189
    • Outcomes of Bariatric surgery in adolescents and youth in an Arab population: a single centre experience

      ea0077p190
    • How does FreeStyle Libre Glucose management indicator (GMI) compare with HbA1c and fructosamine in patients with type 1 diabetes and what are the determinants of the difference?

      ea0077p191
    • N-acetylmuramoyl-L-alanine amidase is a biomarker for remission of type 2 diabetes after bariatric surgery

      ea0077p192
    • Magnesium: The forgotten sibling of electrolytes. A study of two audits conducted over 4 years

      ea0077p193
    • Abstract unavailable

      ea0077p194
    • Diabetes and Young COVID: A two country and two wave study of associations

      ea0077p195
    • Studies of the novel essential invadolysin metalloprotease in human blood

      ea0077p196
    • Case report of a Patient With Maturity Onset Diabetes of the Young 6: a novel NEUROD1 mutation

      ea0077p197
    • Corticosterone excess alters metabolic rate in male and female C57BL/6J mice

      ea0077p198
    • Paraneoplastic Insulin Resistance Syndrome: a case of Fibromatosis (Desmoid Tumour)

      ea0077p199
    • Management of the common within the uncommon: Euglycemic ketoacidosis in Bloom’s syndrome

      ea0077p200
    • Phospho-regulation of Acetyl-CoA-Carboxylase (ACC1) in Pancreatic Beta Cells

      ea0077p201
    • Estimation of body fatness in obesity and partial lipodystrophy in relation to eligibility for bariatric surgery: What should be measured?

      ea0077p202
    • An Audit assessing Management of COVID patients on Dexamethasone with High Capillary Blood Glucose (CBGs) from 01/01/21 to 19/3/21

      ea0077p203
    • Early detection of Peripheral Diabetic Neuropathy - A correlative study of symptoms with Digital Biothesiometry

      ea0077p204
    • Assessing and Improving junior doctors’ knowledge and confidence in managing Diabetes Mellitus in the end-of-life setting

      ea0077p205
    • A quality improvement project to assess the management of diabetes in out-patient clinic as per the NICE guidelines

      ea0077p206
    • Omeprazole induced hypomagnesemia leading to hypocalcemia

      ea0077p207
    • The unmasking of chronic diabetes mellitus, presenting as severe diabetic ketoacidosis following traumatic pancreatic injury, without pancreatitis

      ea0077p208
    • Gender-specific prevalence of hyperuricemia and association with metabolic disorders in China: a hospital population based retrospective real-world study

      ea0077p209
  • Neuroendocrinology and Pituitary
  • • The role of FGF signaling pathway in the pituitary stem cell compartment

      ea0077p78
    • MRI bone shape in patients with acromegaly: a novel technique for the characterisation of the acromegalic arthropathy

      ea0077p79
    • ACROBAT Advance: progress report on a study of long-term safety and efficacy of paltusotine for the treatment of acromegaly

      ea0077p80
    • Is gigantism different from acromegaly in terms of causes of death, comorbidities and treatment? A preliminary retrospective study of 156 UK giants

      ea0077p81
    • Pituitary and gonadal axes in patients with ’Long COVID’: post hoc analysis

      ea0077p82
    • Screening for diabetes insipidus with copeptin after overnight water deprivation

      ea0077p83
    • Cinnamomum zeylanicum bark extract showed ameliorative properties against streptozotocin-induced insulin resistance in the hippocampus of experimental wistar rat

      ea0077p84
    • Clinical presentation of 209 surgically operated non-functioning pituitary macroadenomas

      ea0077p85
    • A rare case of sellar pathology: Coinciding IgG4-related hypophysitis and pituitary adenoma

      ea0077p86
    • Persistent gestational diabetes insipidus

      ea0077p87
    • Effects of ethanol extract of allium sativum L. On the hippocampus of male wistar rats with streptozotocin-induced brain insulin resistance

      ea0077p88
    • New presentation of asymptomatic acromegaly in patients with macroprolactinomas

      ea0077p89
    • Hypo and hypernatraemia on admission are associated with increased length of stay in unselected acute hospital admissions

      ea0077p90
    • Rathke’s cleft cyst with a very unusual course

      ea0077p91
    • Age- gender- and tanner stage-specific reference intervals for serum insulin-like growth factor binding protein 3 (IGFBP-3) and the insulin-like growth factor I (IGF-I) to IGFBP-3 molar ratios in healthy school children of a north indian city

      ea0077p92
    • Healthcare professionals’ survey on the inpatient safety of Diabetes Insipidus

      ea0077p93
    • A case of pituitary abscess - a rare clinical entity

      ea0077p94
    • Coronary artery bypass grafting (CABG)-related pituitary apoplexy

      ea0077p95
    • Primary empty sella syndrome (PESS) audit in a southwest tertiary hospital

      ea0077p96
    • Management of Complicated Pit-1 staining Non-functioning Pituitary macroadenoma in Pregnancy

      ea0077p97
    • Hypopituitarism secondary to hydrocephalus associated with tectal plate tumour

      ea0077p98
    • Retrospective audit of clinical, biochemical and radiological features of Pituitary apoplexy

      ea0077p99
    • Conservative management of Cushing’s in COVID times: A case series and meta-analysis

      ea0077p100
    • Worst headache of my life

      ea0077p101
    • Management of cranial Diabetes Insipidus in a tertiary centre - clinical outcomes and patient perception of care

      ea0077p210
    • Digital transformation of a hyponatraemia toolkit: impact on clinical practice

      ea0077p211
    • Cabergoline treatment in human primary non-functioning pituitary adenomas

      ea0077p212
    • The use of low dose tolvaptan for the treatment for hyponatraemia - a retrospective analysis of its efficacy and safety

      ea0077p213
    • Pregnancy and neuroendocrine neoplasms

      ea0077p214
    • Prevalence of cholelithiasis in somatostatin analogues treated Acromegaly patients

      ea0077p215
    • Neuroendocrine Tumours (NETS): Telemedicine and patient satisfaction in the COVID-19 pandemic: A patient survey from a European Neuroendocrine Tumour Centre of Excellence

      ea0077p216
    • Comparison of cardiovascular outcomes of radiotherapy vs non-radiotherapy cohort of Acromegaly patients

      ea0077p217
    • Imaging screening for lung cancer required at diagnosis and at 6 months after established diagnosis of SIADH? A retrospective Audit of real-life clinical practice

      ea0077p218
    • Pituitary apoplexy- a retrospective analysis of clinical features, management and outcomes

      ea0077p219
    • Multiple Cell Line Pituitary Adenoma associated with PIT-1 and TPIT lineage cells resulting in acromegaly with ACTH dependent Cushing’s: a case report

      ea0077p220
    • The usefulness of measuring neurone specific enolase in patients seen in the Endocrine Clinic

      ea0077p221
    • SDHD missense pathogenic variants: not always benign

      ea0077p222
    • Generation of normative data on serum insulin-like growth factor I (IGF-I) in healthy school children of a north indian city

      ea0077p223
    • Three cases of metastatic spinal cord compression secondary to malignant pheochromocytoma and paraganglioma

      ea0077p224
    • Utility of prolactin measurement in inferior petrosal sinus samples when investigating ACTH dependent cushing’s

      ea0077p225
    • Complete third nerve oculomotor nerve palsy as initial presentation of pituitary tuberculosis

      ea0077p226
    • Ectopic Cushing’s syndrome: challenging the stereotype

      ea0077p227
    • Rhabdomyosarcoma in Carney complex - Is there an association

      ea0077p228
    • Case report: pituitary metastasis and Its diagnostic complexity

      ea0077p229
    • Immune check point inhibitor induced hypophysitis with normal pituitary imaging

      ea0077p230
    • A challenging adrenal incidentaloma

      ea0077p231
    • Dramatic resolution of a pituitary macroadenoma: non-functioning or prolactin-secreting?

      ea0077p232
  • Reproductive Endocrinology
  • • Differentially glycosylated FSHR ligands as potential modulators of FSHR quaternary complexes and FSHR-dependent signalling

      ea0077p102
    • Maternal fetuin-A (AHSG) serum levels are altered in pregnancies complicated by gestational diabetes and are associated with pathological fetal growth

      ea0077p103
    • An exploration of the association between CAG repeat status and mortality in men

      ea0077p104
    • Abstract unavailable

      ea0077p105
    • Pregnancies in women with Turner Syndrome: A retrospective multicentre UK study

      ea0077p106
    • A randomised controlled trial on the effect of very-low-calorie diet (VLCD) vs. an energy deficit diet, in women with the polycystic ovary syndrome (PCOS) - remission PCOS

      ea0077p107
    • HIIT’ing or MISS’ing the optimal management of Polycystic Ovary syndrome: A systematic review and meta-analysis of high-versus moderate-intensity exercise prescription

      ea0077p108
    • The relationship between polycystic ovarian syndrome and fractures: A Mendelian randomization study using the UK Biobank

      ea0077p109
    • Clinical characteristics associated with testosterone prescribing in men in primary care

      ea0077p110
    • An investigation of androgen-responsive non-coding RNAs in boys with atypical genitalia without genetic variants in the androgen receptor (AR)

      ea0077p111
    • What is the prevalence and pattern of cancers in Turner syndrome? A single centre cohort study

      ea0077p112
    • PCOS SEVa: High prevalence anxiety and body dysmorphia in women with PCOS in the UK and India

      ea0077p113
    • PCOS pearls - gathering perceptions and opinions from lived experiences of people with polycystic ovary syndrome

      ea0077p114
    • Disentangling Turner syndrome and Leri-Weill Dyschondrosteosis; the importance of genetic assessment in the management of Turner Syndrome

      ea0077p115
    • A rare case report of spontaneous pregnancy in long standing premature ovarian insufficiency secondary to chemotherapy

      ea0077p116
    • Spontaneous adrenal haemorrhage and adrenal deficiency during third trimester - successful delivery with conservative management: A case report

      ea0077p117
    • In vitro effects of dihydrotestosterone (DHT) on gonadotropin receptor function and steroidogenesis in human granulosa lutein cells

      ea0077p233
    • Reproductive health disturbance in the era of the COVID-19 pandemic

      ea0077p234
    • Wilms’ Tumour-1 (WT1) regulates proliferation, apoptosis and endocrine function in a model of human granulosa cells

      ea0077p235
    • Increased levels of testosterone associated with polycystic ovary syndrome (PCOS) negatively affect HOXA10 and integrin [beta]3 expression in endometrial cells and embryo attachment using a trophoblast cell spheroid model

      ea0077p236
    • Impact of pharmacological Interventions on androgen hormones in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials

      ea0077p237
    • Clinical utility of free androgen index (FAI) in the assessment of PCOS

      ea0077p238
    • The rate of progression of atherosclerosis in menopause is associated with levels of circulating amyloid beta 1-40

      ea0077p239
    • Effect of pharmacological interventions on lipid profiles and C-reactive protein in polycystic ovary syndrome: a systematic review and meta-analysis

      ea0077p240
    • Efficacy and safety of androgens in transgender medicine

      ea0077p241
    • Assessing emotional wellbeing in women with PCOS living in the UK and Indian community: the Blue Morpho Survey

      ea0077p242
    • The effect of exogenous kisspeptin administration in a novel mouse model of hypothalamic amenorrhoea

      ea0077p243
    • Service evaluation of patients referred for PCOS - Are we doing enough to diagnose and manage them well?

      ea0077p244
    • COVID19 in Turner Syndrome; results of a self-completed website survey

      ea0077p245
    • The Impact of COVID-19 on Endocrine Treatments from a patient perspective - effect on parenteral testosterone

      ea0077p246
    • A case of reversible congenital hypogonadotropic hypogonadism

      ea0077p247
  • Thyroid
  • • Cost-effectiveness analysis of liothyronine for the management of treatment unresponsive hypothyroidism based on latest evidence

      ea0077p118
    • Conundrum of Thyroid Function Tests

      ea0077p119
    • Service review on the use of TRAB antibodies for patients with hyperthyroidism

      ea0077p120
    • Thionamide-associated hepatitis: A forever clinical conundrum

      ea0077p121
    • A family with euthyroid hyperthyroxinaemia

      ea0077p122
    • The impact of intraoperative elements on postoperative hypoparathyroidism in patients after total thyroidectomy

      ea0077p123
    • Two Unusual Cases of Subacute Thyroiditis (SAT) and management

      ea0077p124
    • Catastrophic complication related to uncontrolled thyrotoxicosis

      ea0077p125
    • Conversion of Hypothyroidism to hyperthyroidism: a rare but not an uncommon phenomenon

      ea0077p126
    • Can a person with long standing hypothyroidism develop thyrotoxicosis despite stopping thyroxine?

      ea0077p127
    • A case of Transient Neonatal Thyrotoxicosis born to mother with Graves’ Disease

      ea0077p128
    • COVID 19 Related Thyroiditis

      ea0077p129
    • Radioactive Iodine Therapy in Benign Thyroid Disease - results from implementing 2007 RCP Guidelines

      ea0077p248
    • Pulse methylprednisolone as preparation for thyroidectomy for drug-resistant amiodarone-induced thyrotoxicosis

      ea0077p249
    • A case of autoimmune hyperthyroidism in pregnancy after COVID-19 vaccine

      ea0077p250
    • Iodine deficiency causing goitre and deranged thyroid function

      ea0077p251
    • ? Toxic nodule or Thyroid Carcinoma

      ea0077p252
    • A case of Pituitary hyperplasia in patient with Graves’ disease over treated with carbimazole lead to severe hypothyroidism

      ea0077p253
    • Assessment of the efficacy of follicular phase thyroid hormone concentrations in predicting an endometriosis diagnosis

      ea0077p254
    • Graves’ thyrotoxicosis complicated by mental health disorder and twin pregnancy

      ea0077p255
    • Audit of Liothyronine Prescribing at the University Hospitals of Leicester (UHL) NHS Trust

      ea0077p256
    • Hashimoto’s Encephalopathy: organic psychosis vs catatonic schizophrenia

      ea0077p257
    • Case Study: Profound iatrogenic hypothyroidism in early pregnancy secondary to propylthiouracil

      ea0077p258
  • Nursing Practice
  • • Assessing the effectiveness of the endocrine specialist nurses (ESN) hydrocortisone education video created during covid-19 pandemic

      ea0077p130
    • The value of dual energy X-ray absorptiometry (DXA) scan in patients at low risk of fragility fracture

      ea0077p131
    • Systematic review of behavioural change interventions for the prevention of adrenal crisis in adults with primary adrenal insufficiency - An infographic interpretation

      ea0077p132
    • Development of interventions to prevent adrenal crisis - How can application of behaviour change theory and intervention frameworks inform practice?

      ea0077p133
  • Late Breaking
  • • Effect of Dolutegravir on adrenal function in HIV patients on ARVs using serum and salivary cortisol assay

      ea0077lb1
    • Effect of Dolutegravir on adrenal function in HIV patients on ARVs using serum and salivary cortisol assay

      ea0077lb1 (1)
    • The importance of high-volume specialist centres. An audit of bilateral adrenal vein catheterization success rates

      ea0077lb3
    • Not your regular incidentaloma

      ea0077lb4
    • A rare presentation of malignant paraganglioma

      ea0077lb5
    • An unusually small but symptomatic Phaeochromocytoma

      ea0077lb6
    • Vitamin D deficiency in female healthcare workers during a pandemic

      ea0077lb7
    • An atypical case of hypercalcaemia extending into adulthood in a patient with Williams-Beuren Syndrome

      ea0077lb8
    • Oncogenic osteomalacia: a rare cause of hypophosphataemia

      ea0077lb9
    • Interpreting hyponatraemia in the wider context and the use of desmopressin outside of endocrinology

      ea0077lb10
    • Mass spectrometry imaging for simultaneous analysis of lipid biomarkers, lysophosphatidic acid (LPAs) and lysophosphatidyl choline (LPCs), in fibrotic liver tissue

      ea0077lb11
    • Hypoxia re-programmes adipocyte metabolism to drive cancer cell proliferation

      ea0077lb12
    • Fatty acids prevent normal activation of key HIF-1[alpha] regulated genes during hypoxia in HEK293T cells

      ea0077lb13
    • Abnormalities of glucagon suppression and stimulation of insulin secretion in response to rising glucose concentrations interact in impaired fasting glucose and impaired glucose tolerance

      ea0077lb14
    • Development and testing of a novel 'GrowthMonitor' Smartphone App for growth monitoring and the detection of growth disorders

      ea0077lb15
    • Management of hypoglycemia in hospitalized patients with diabetes

      ea0077lb16
    • Challenges in the diagnosis and management of type 1 diabetes in older adults

      ea0077lb17
    • Prevalence rate of undiagnosed diabetes in an asymptomatic population

      ea0077lb18
    • Post noradrenaline infusion induced gangrene of the toes

      ea0077lb19
    • Long-term clinical outcomes for pituitary cysts: experience of the multi-disciplinary team at the royal victoria infirmary

      ea0077lb20
    • Long-term Clinical Outcomes for Cushing's Disease: experience of the multi-disciplinary team at the Royal Victoria Infirmary

      ea0077lb21
    • Effect of Enzalutamide on cortisol dynamics

      ea0077lb22
    • Unexplained hypoglycaemia in a patient with craniopharyngioma and GAD positive encephalitis

      ea0077lb23
    • Hypopituitarism caused by Langerhans Cell Histiocytosis

      ea0077lb24
    • Nelson syndrome - invasive macro-adenoma revealed by pituitary apoplexy

      ea0077lb25
    • A microfluidics approach of mimicking an obese maternal metabolic environment identifies modified pathways in the endometrial epithelium that may be important for implantation

      ea0077lb26
    • Efficacy of oestrogen implant in transwomen as hormone replacement therapy

      ea0077lb27
    • A Heavy Heart

      ea0077lb28
    • Is Aloe vera always beneficial?

      ea0077lb29
    • Pericarditis and sub-acute thyroiditis complicating Pfizer-BioNTech Covid-19 vaccination

      ea0077lb30
    • Mapping of aldosterone and glucocorticoids in mouse kidney using mass spectrometry imaging

      ea0077lb31
    • Dolutegravir increases Peritoenal fat of adult HIV patients but not serum lipids. A preliminary finding of a Pilot study

      ea0077lb32
    • Complex management of unilateral post-Covid-19 adrenal haemorrhage during pregnancy

      ea0077lb33
    • Adrenal lymphoma 'The Great Imitator'

      ea0077lb34
    • Two cases of peri-operative adrenal crises: lessons in patient safety

      ea0077lb35
    • Small cell lung cancer presenting as hyperglycaemia and paraneoplastic syndrome

      ea0077lb36
    • Thyroid dysfunction with Zoledronic acid infusion for osteoporosis

      ea0077lb37
    • An interesting case of Hypophosphataemia: Oncogenic Osteomalacia

      ea0077lb38
    • Metabolomic analysis of succinate dehydrogenase subunit knockout in phaeochromocytoma and neuroblastoma cell lines

      ea0077lb39
    • Novel ultrasound approaches permit the visualisation of the microvascular effects of glucagon-like peptide-2 in the gut with unprecedented resolution

      ea0077lb40
    • Intestinal Organoids as Vehicles for Therapeutic Peptide Delivery

      ea0077lb41
    • Identifying biomarkers of psoriasis-driven metabolic disease

      ea0077lb42
    • GLP-1 receptor agonists offer protection against fatty acid induced insulin resistance in 3D kidney spheroids

      ea0077lb43
    • Depression and islet function during pregnancy: Generation of a depressive phenotype using UCMS

      ea0077lb44
    • Challenges and solutions for the management of inpatient diabetes care during and post COVID 19 pandemic

      ea0077lb45
    • Improvement in the delivery of Diabetes foot care after implementing a restructured referral form: An experience from a District General Hospital

      ea0077lb46
    • Evening Chronotype and type 2 diabetes: what link in menopause?

      ea0077lb47
    • Post-HUS diabetes mellitus in 3 years old child: the challenging management of glucose control and the advantages of SAP therapy initiation

      ea0077lb48
    • Diabetes and Deafness: Think outside the box

      ea0077lb49
    • A plasma and serum 5-HIAA assay with comparable diagnostic performance in patients with neuroendocrine tumours

      ea0077lb50
    • An unusual recurrence of a non-functioning pituitary adenoma as mantle cell lymphoma

      ea0077lb51
    • Central serous retinopathy as a manifestation of cushing's disease - two case reports

      ea0077lb52
    • Central diabetes insipidus as initial presentation of Acute myeloid Leukaemia monosomy 7

      ea0077lb53
    • An unusual neuroglycopenic presentation in a case of Insulinoma

      ea0077lb54
    • Optimising diagnostic and management clarity in two opposing sodium centenarians

      ea0077lb55
    • Placental levels of miR-1-3p and miR-133a-3p are decreased in pregnancies complicated gestational diabetes with large-for-gestational-age birth outcomes and may be influencing vascular smooth muscle differentiation

      ea0077lb56
    • A Novel LC-MS/MS Method for the Simultaneous Detection of Multiple Steroids in Plasma and Tissue Lysates, used to verify Cell Autonomous Sex Identity in birds

      ea0077lb57
    • Silver Russell syndrome - Rare case of sibling

      ea0077lb58
    • Study of the efficacy of sublingual route administration of levothyroxine Na nablets vs oral route in cases with refractory primary hypothyroidism

      ea0077lb59
    • Iodinated Contrast-induced Thyrotoxicosis

      ea0077lb60