Endocrine Abstracts

Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome encompasses a spectrum of conditions from hepatic steatosis through to cirrhosis; obesity is a known risk factor. It remains unclear why intra-hepatocellular fat starts to accumulate, but it is likely to involve an imbalance between fatty acid delivery to the liver, fatty acid synthesis and oxidation within the liver and triglyceride export from the liver. Studying hepatic metabolism...