Endocrine Abstracts

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Society for Endocrinology BES 2018

Glasgow, UK
19 Nov 2018 - 21 Nov 2018

The Society for Endocrinology BES will take place 19-21 Nov 2018 in Glasgow. Come and exchange knowledge, share experiences and strengthen collaborations across our global community of endocrinologists.

Society for Endocrinology BES 2018
- Plenary Lectures
- Society for Endocrinology International Medal Lecture
- - Puberty: what are the neuroendocrine triggers for the biological end of childhood?
    
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- Society for Endocrinology Starling Medal Lecture
- - Hepatic fatty acid synthesis and partitioning: the effect of metabolic and nutritional state
    
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- Society for Endocrinology Medal Lecture
- - Endocrine systems are dynamic: Lessons from the hypothalamic-pituitary-adrenal axis
    
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- Society for Endocrinology Transatlantic Medal Lecture
- - Circadian Clock Genes and the Transcriptional Architecture of the Clock Mechanism
    
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- Clinical Endocrinology Trust Visiting Professor Lecture
- - SIAD; a modern approach to diagnosis and management
    
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- Clinical Endocrinology Trust Lecture
- - Sex, steroids and development - clinical research from the NHS
    
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- British Thyroid Association Pitt-Rivers Lecture
- - How should we define optimal thyroid function?
    
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- Society for Endocrinology Dale Medal Lecture
- - Disorders of Thyroid Hormone Action: insights into biological processes
    
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- Society for Endocrinology European Medal Lecture
- - Molecular mechanisms in primary aldosteronism
    
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- Society for Endocrinology Jubilee Lecture
- - Ups and downs of nuclear receptor action
    
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Society for Endocrinology Journal Awards
- Society for Endocrinology Journal Award – Journal of Endocrinology
- - Abstract unavailable
    
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- Society for Endocrinology Journal Award – Journal of Molecular Endocrinology
- - Abstract unavailable
    
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- Society for Endocrinology Journal Award – Endocrine-Related Cancer
- - Abstract unavailable
    
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- Society for Endocrinology Journal Award – Clinical Endocrinology
- - Abstract unavailable
    
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Symposia
- Curing diabetes
- - Immunotherapy for Type 1 diabetes
    
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  - State of the art in islet cell therapy: preclinical advances in graft revascularization
    
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  - Abstract unavailable
    
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- Big data and bone disease
- - Osteoporosis Mega GWAS: Paths to causal proteins
    
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  - Abstract unavailable
    
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  - How rare bone disease will advance bone biology (Role of the Musculoskeletal GeCIP)
    
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- Horizons in adrenal medicine
- - Novel strategies in glucocorticoid replacement
    
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  - Urine steroid metabolomics in adrenal incidentaloma
    
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  - Abstract unavailable
    
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- New treatments for bone disorders
- - Abaloparatide Treatment for Osteoporosis
    
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  - New treatments for rare bone disease
    
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  - Rare bone disorders: New genes, biology and therapeutic targets
    
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- Breast cancer
- - Diving into the dark matter of the breast cancer genome
    
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  - Metabolic pathways regulating breast cancer in obesity
    
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  - The Estrogen Receptor chromatin binding landscape in human tumors
    
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- The most important nine months; impact of maternal health
- - Abstract unavailable
    
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  - Impact of Maternal Obesity/Diabetes during Pregnancy and Child Health
    
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  - Early-life stress increases vulnerability to develop cognitive and metabolic dysfunction: a focus on inflammation and nutrition
    
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- The microbiome in endocrine disease
- - The gut microbiota in ageing and inflammation
    
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  - The role of the gut microbiome in obesity
    
    ea0059s7.2
  - A Role for the Microbiome in Graves' Disease and Orbitopathy?
    
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- Thyroid in pregnancy
- - TABLET TRIAL - implications for targeted levothyroxine in pregnancy
    
    ea0059s8.1
  - CATS Obstetric and development - implications for thyroid screening in pregnancy
    
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  - Iodine supplementation in pregnancy and effect on offspring neurodevelopment
    
    ea0059s8.3
- Introduction and prevention of gonadal function
- - How do I differentiate hypog hypog from constitutional delay?
    
    ea0059s9.1
  - Induction of Spermatogenesis
    
    ea0059s9.2
  - Abstract unavailable
    
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- Pancreatic NETs – an update
- - Managing Pancreatic Neuroendocrine Tumours in MEN1
    
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  - Advances in endoscopic ultrasound and endotherapy for pancreatic neuroendocrine tumour
    
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  - The genomic landscape of pancreatic neuroendocrine tumours
    
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Early Career Symposia
- Navigating the academic
- - The scientific fellowship route
    
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  - Early Careers: navigating the academic pathway. The clinical academic route
    
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  - Abstract unavailable
    
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  - Surviving academia: The lectureship route
    
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  - Abstract unavailable
    
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Clinical Management Workshops
- Workshop 1: Aggressive pituitary tumours
- - How and when to use temozolomide in pituitary tumours
    
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  - When to intervene in recurring pituitary tumours: the role of revision surgery
    
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  - Proton Beam Therapy: The future of radiotherapy?
    
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- Workshop 2: Endocrine emergencies
- - Adrenal crisis: prevention and management
    
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  - A phaeochromocytoma crisis
    
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  - Thyrotoxic crises
    
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- Workshop 3: How do I. . . (1)
- - How Do I\.\.Manage Diarrhoea in Patients with NETs
    
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  - Abstract unavailable
    
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  - Abstract unavailable
    
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  - Abstract unavailable
    
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  - Abstract unavailable
    
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  - Abstract unavailable
    
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- Workshop 4: Treating troublesome menopausal symptoms
- - HRT: Efficacy and Safety
    
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  - Non-hormonal therapies for climacteric symptoms
    
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  - Neurokinin B antagonism - novel therapy for menopausal flushing
    
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- Workshop 5: How do I. . . (2)
- - How do I manage endocrinopathies in HIV patients?
    
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  - How do I manage Paget's disease
    
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  - How do I manage thyroid eye disease?
    
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  - Abstract unavailable
    
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  - How do I know which non-diabetic patients could benefit from a GLP-1 analogue
    
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  - How Do I\..Investigate Sweating
    
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APPLIED PHYSIOLOGY WORKSHOP
- GPCRS: hotspots and complexes
- - Calcium-sensing at 25 years
    
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  - FSH, Body Fat, Bone Mass and Biological Aging
    
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  - The nanodomain organization of GPCR signalling: lessons from TSH receptors and beyond
    
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- Metabolites as hormones
- - Metabolic and microbial investigation of weight loss surgery
    
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  - Short chain fatty acid signalling in human health and disease
    
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  - Abstract unavailable
    
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Early Career Prize Lectures
- (1)
- - Neurokinin 3 receptor antagonism - the magic bullet for hot flushes?
    
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  - The Importance of Local Steroid Action in the Regulation of Fertility
    
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Meet the Expert Sessions
- What the endocrinologist needs to know about genetics
- - What the endocrinologist needs to know about genetics?
    
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- GC metabolic health
- - Glucocorticoids in metabolic health: Effects of selective GR modulators
    
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- Biochemistry masterclass
- - Insulin assay
    
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  - Insulin-like growth factor-1 (IGF-I) assays
    
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  - Abstract unavailable
    
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- Brown adipose tissue
- - Brown adipose tissue: A neuroendocrine target
    
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- Non-surgical management of incurable thyroid cancer
- - Non-surgical management of incurable thyroid cancer
    
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- Gender dysphoria
- - Gender dysphoria: Treatment and out comes
    
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- A year in thyroid
- - Abstract unavailable
    
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- Circulating tumour cells in NETS
- - Abstract unavailable
    
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- Pituitary ion channel activity in health and disease
- - Abstract unavailable
    
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- Service Improvements
- - GIRFT (Getting It Right First Time) for Endocrinology, NHS England John A. H. Wass, Professor of Endocrinology, University of Oxford and Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford OX3 7LJ, United Kingdom
    
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  - The Society for Endocrinology peer review scheme
    
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  - Optimising patient outcomes and time management: the perfect MDT
    
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Skills
- Skills 1: Presentation skills
- - How to write an Abstract
    
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  - Abstract unavailable
    
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  - Abstract unavailable
    
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  - Abstract unavailable
    
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  - How do I respond to peer review?
    
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- Skills 2: How do I pass the SCE
- - How Do I pass the SCE Exam?
    
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Master Class
- Masterclass 1: PCOS
- - Polycystic ovary syndrome; The role of androgen excess in disease pathogenesis and metabolic dysfunction
    
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  - Polycystic ovary syndrome: management
    
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Debate
- This house believes that the gut is the conductor of the endocrine orchestra
- - Abstract unavailable
    
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  - Abstract unavailable
    
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Nurse Session
- Nurse Session 1: Pituitary adenomas; beyond surgery
- - Abstract unavailable
    
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  - The role of gamma knife in the management of pituitary adenomas
    
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  - Abstract unavailable
    
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  - Gamma Knife Surgery - a Patient's Perspective
    
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- Nurse Session 2: Adrenal crisis & steroid education; raising the safety bar
- - Abstract unavailable
    
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  - National Education Programme for Patients with Chronic Adrenal Insufficiency
    
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  - Adrenal Crisis-not always the obvious-Case Study 1
    
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  - Adrenal crisis, not always the obvious - Case study
    
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Senior Endocrinologists Session
- (1)
- - Abstract unavailable
    
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  - Plasma Steroid Bioavailability: Hormones, Precursors and Metabolites
    
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  - Why did the Queen die?
    
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Oral Communications
- Translational highlights
- The best of the best
- Obesity & diabetes
- Clinical highlights
- Adrenal
- Neuroendocrinology and Reproduction
Poster Presentations
- Adrenal and steroids
- - Glucocorticoids promote DNA repair to reduce efficacy of radiotherapy in Glioblastoma
    
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  - 11[beta]-HSD type 1 inhibitor ameliorates metabolic disorders associated with hypercortisolemia: A clinical trial to assess its safety and efficacy in Japanese patients with refractory Cushing's syndrome and subclinical Cushing's syndrome
    
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  - Mass spectrometry-based assessment of childhood androgen excess in 487 consecutive patients
    
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  - Feasibility of immunological markers and osteocalcin as a barometer of glucocorticoid replacement
    
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  - A model to predict Hypothalamic-Pituitary-Adrenal (HPA) axis recovery at 6 weeks post trans sphenoidal adenomectomy: a single-centre retrospective analysis
    
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  - Increased urinary glucocorticoids in obese pregnancy suggest a potential mechanism underlying macrosomia
    
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  - Salivary cortisol determination using the Roche generation II assay
    
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  - Post-operative haemodynamic instability after adrenalectomy for phaeochromocytoma: is routine intensive care admission necessary?
    
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  - Discordance between imaging and adrenal vein sampling in primary aldosteronism
    
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  - Exploring the utility of renin measurements in the routine management of salt-wasting congenital adrenal hyperplasia
    
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  - Androgen deprivation therapy causes selective loss of levator ani and leg muscle volumes
    
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  - Newly diagnosed adrenal patients are poorly prepared to manage adrenal crisis
    
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  - Adrenalectomy for removal of adrenal incidentalomas: are we being too cautious? A Retrospective Database Analysis
    
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  - Characteristics of patients with normal adrenal imaging in primary aldosteronism
    
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  - Natural history of adrenal incidentalomas with and without mild autonomous cortisol excess; a systematic review and meta-analysis
    
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  - Can morning salivary cortisol or cortisone predict short synacthen test outcome?
    
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  - Addressing adrenal incidentalomas (AIs): a snapshot of the investigation of AIs in a tertiary endocrine centre and the effect of implementing a local management pathway
    
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  - The role of plasma metanephrines and plasma catecholamines in the biochemical testing for Pheochromocytoma
    
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  - Utility of Adrenal vein sampling (AVS) in the investigation of functional bilateral adrenal adenomas
    
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  - Addison's at high altitude - developing an evidence based patient information resource for Addison's patients who travel to high altitude
    
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  - Does a 60 minute sample in addition to a 30 minute sample for cortisol in the Short Synacthen Test alter patient management?
    
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  - A review of short synacthen test results: what is the cut-off?
    
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  - Analysis of diagnosis and growth dynamics of adrenal incidentalomas in a large general hospital
    
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  - Current management of adrenal incidentalomas- a United Kingdom single centre experience
    
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  - Secondary diabetes mellitus in patients with endogenous cushing's syndrome
    
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  - Evaluation of glucocorticoid secretion in an adrenal incidentaloma cohort
    
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  - Prevalence rate, characteristics and predictive factors of primary aldosteronism among hypertensive patients who had aldosterone-renin ratio screening in Southern Thailand: A retrospective, cross-sectional study
    
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  - How useful is 24 hour Urinary Free Cortisol as a screening tool for Cushing's syndrome?
    
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  - Management outcome of phaeochromocytoma over 10 years (2008-2018) in a Tertiary Centre, UK
    
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  - Analysing management and follow up of adrenal incidentalomas
    
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  - Audit of Short synacthen test at East Sussex Healthcare NHS trust since introducing new Roche cortisol assay: Diabetes and Endocrinology dept., Biochemistry dept., East Sussex Healthcare NHS trust
    
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  - Glucocorticoid activation by 11[beta]-HSD1 is increased in M1, but not M2 polarised macrophages, where it determines pro-inflammatory cytokine expression
    
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  - Prolonged exposur to methylprednisolone disrupt the rat adrenal gland steroidogenic pathway and affect intra-adrenal inflammatory mediators
    
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  - Cigarette smoke extract and cotinine, but not nicotine, alter the steroidogenic capacity of adrenocortical cells
    
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  - Peripheral glucocorticoid metabolism selectively modulates innate immune receptor RIG-I
    
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  - Modelling glucocorticoid-induced HPA axis suppression in mice
    
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  - Time-dependent cortisol turnover in tissues using stable isotope tracers and MALDI Mass Spectrometry (MS) sampling
    
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  - QRT-PCR analysis of the effect of in utero exposure to sewage sludge on steroidogenic gene expression in ovine foetal adrenal gland
    
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- Bone and calcium
- - Management of hypoparathyroidism against European guidelines: Experience of a large teaching hospital
    
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  - Symptom documentation in patients with primary hyperparathyroidism before and after the introduction of a symptom scoring questionnaire
    
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  - Management of osteogenesis imperfecta in adulthood - a single centre experience
    
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  - Vitamin D status is associated with physical function, frailty and mortality in older patients admitted with acute illness
    
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  - Conventional treatment of chronic hypoparathyroidism results in suboptimal calcium homeostasis
    
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  - Prevalence and risk factors of low vitamin D in Kano, Northwestern Nigeria
    
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  - Evaluation of effect of primary hyperparathyroidism and parathyroidectomy on blood pressure
    
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  - Role of Ultrasound Neck (US), sestamibi Scintigraphy and Multidisciplinary team (MDT) discussion prior to intervention in the localization of parathyroid lesion
    
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  - Clinical efficacy of cinacalcet in primary hyperparathyroidism in reducing calcium and admission avoidance
    
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  - Postoperative hypocalcaemia after thyroidectomy and parathyroidectomy: A streamlined cost effective treatment pathway
    
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  - Primary Hyperparathyroidism (PHPT) audit
    
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  - Prevalence of metabolic bone disorders in patients with bony stress injuries - implications for endocrine services
    
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  - Chromolaena odorata and Tithonia diversifolia synergistically stimulate kidney erythropoietin and repress cyclin-dependent kinase inhibitors in the bone marrow of Wistar rats
    
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  - Utility of Whole Genome Sequencing in diagnosing complex disorders: lesson from renal tubular disorders
    
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  - Identification of a frame-shifting c.348dupC GNAS mutation in a family with Pseudohypoparathyroidism type 1a (PHP1a) by Whole Genome Sequencing
    
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  - Risk of bone fracture is not increased in women with TS compared to women with ovarian failure
    
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  - Resistant hypocalcemia post parathyroidectomy attributed to imatinib
    
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- Clinical biochemistry
- - Interference of Asfotase Alfa in immunoassays using ALP detection systems
    
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  - Genetic susceptibility to type 1 diabetes: genomic variants in the vitamin D pathway
    
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  - A cross-sectional study of sensitivity and specificity of late-night salivary cortisol in a single-centre heterogenous population
    
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  - A novel metaoblic index as a predictor of mortality in intensive care patients
    
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  - Low plasma glucose results from primary care are not associated with morbidity, mortality or underlying endogenous hypolgyaemic disorders
    
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  - An analysis of hypocalcaemia post thyroidectomy: diagnosis and predictors
    
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  - Urine steroid profiles: what can they do for me?
    
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  - Hypernatraemia in acute unselected general medical inpatients: clinically relevant associations
    
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  - Gitelman Syndrome (GS) is a rare, salt-losing tubulopathy. Prevalence 1 in 40,000 higher in Asia. GS is an autosomal recessively inherited disease with a wide clinical spectrum, usually seen in adolescents and adults. It is reported that function loss develops in the sodium chloride cotransporter system in the distal renal tubule as the result of SLC12A3 gene mutation
    
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  - An oestrogen profiling mass spectrometry method using N-Methyl Pyridine-3-sulfonyl chloride derivatisation
    
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- Clinical practice, governance & case reports
- - Cranial Diabetes Insipidus - A survey of patient safety concerns in secondary care
    
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  - An audit of electronic consultations for provision of endocrine specialist advice
    
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  - Utilization of the internet for health-related information among endocrinology patients
    
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  - Patient perception of provision of care for multiple endocrine neoplasia disorders in the UK compared to other EU member states
    
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  - Physiological versus synthetic oestrogen therapy and bone mineral density in premature ovarian insufficiency
    
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  - Review of the reasons cited by GPs who refuse to prescribe medications recommended by the London gender identity clinic
    
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  - Patient perception of quality of care for multiple endocrine neoplasia disorders in the UK compared to other EU countries
    
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  - Transition in Turner syndrome
    
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  - A retrospective analysis of electronic endocrinology advice and guidance via NHS e-referral service at University Hospitals Leicester NHS Trust
    
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  - Pituitary MRIs in hypogonadotrophic hypogonadism - essential or essentially a waste of time?
    
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  - Outcomes of endoscopic surgical intervention for acromegaly - the Wessex experience
    
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  - Management of patients with gynaecomastia in a single centre - a retrospective analysis
    
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  - An audit of vitamin D supplementation in pregnancy in an ante-natal centre in Birmingham
    
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  - Thyroid shared care - a nurse-led, virtual service for our patients
    
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  - Are we adhering to Simon Broome criteria for referrals for Familial Hypercholesterolaemia genetic mutation at Queen Alexandra hospital and are there any clear differentiators between the 2 outcome groups?
    
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  - A re-audit on treatment outcomes of patients with acromegaly in the sussex pituitary multidisciplinary team
    
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  - ICP based approach to DKA management improves performance
    
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  - Evaluation of quality of care provided to patients with Turner syndrome (TS) cared for by the University Hospitals of Leicester NHS Trust
    
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- Diabetes & cardiovascular
- - Differential regulation of urinary peptides between men and women at early stages of diabetic nephropathy
    
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  - Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice
    
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  - The role of dietary protein intake on glycaemic variables in a young healthy south-asian population at risk of type 2 diabetes
    
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  - Electronic inpatient diabetes referrals in a university teaching hospital - A glasgow experience
    
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  - Assessment of liver imaging in a diabetic population with an abnormal AST-to-platelet-ratio-index (APRI) or Fibrosis-4-score (FIB4)
    
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  - Comparison of the impact of camel milk and cow milk on blood glucose, insulin and GLP1 in healthy individuals
    
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  - Patients with diabetes are at no greater risk for contrast induced nephropathy than those without diabetes?
    
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  - Glycaemic control in group 2 license holders with diabetes mellitus
    
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  - Metformin use and vitamin B12 deficiency
    
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  - Clinical characteristics of men and women attending a secondary care diabetic nephropathy service
    
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  - Diabetes related distress in a Nigerian Tertiary Hospital: A preliminary report
    
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  - Hearing impairment in nigerians with type 2 diabetes mellitus attending fmc Lokoja
    
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  - Hyperglycaemic emergencies as seen at a tertiary hospital in south western nigeria
    
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  - Frequency and predictors of sexual dysfunctions among male Nigerians with diabetes mellitus (A Preliminary report)
    
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  - Audit of gestational diabetes in a District General Hospital
    
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  - Glucocorticoids promote mitochondrial fatty acid oxidation in fetal cardiomyocytes
    
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  - Glucocorticoid receptor deficiency alters cardiomyocyte DNA replication in neonatal mice
    
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  - Characterisation of diabetes mellitus in turner syndrome - Turner syndrome life course project
    
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  - Skin-endocrine regulation of whole-body metabolism
    
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  - Development of a Novel Estrogen Metabolite LC-MS/MS Assay: Influence of 16[alpha]OHE2 in Pulmonary Arterial Hypertension
    
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  - Glucose regulates miR-184 via AMP-activated protein kinase (AMPK) in pancreatic [beta]-cells
    
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  - State of glutathione system in patients with type 2 diabetes
    
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  - Bright and specific far-red labels for visualizing endogenous glucagon-like peptide-1 receptors
    
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  - Anacardium occidentale upregulates GLP-I and Insulin Gene Expression in Normoglycemic Rats
    
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  - Nrf2 mediated protection against hypoglycaemia induced cognitive deficits in type 1 diabetes
    
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  - Activation of the adhesion GPCR GPR56 by a synthetic tethered agonist improvesislet [beta]-cell function
    
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  - Prevalence of Kock's diseases among diabetes patient attending state Specialist Hosital Akure South West Nigeria
    
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- Neoplasia, cancer & late effects
- - Cholesterol metabolism and chemo-resistance in breast cancer
    
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  - Use of glucocorticoids following immunotherapy for cancer
    
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  - Very long term follow up of patients treated for childhood leukaemia - a single centre experience
    
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  - The analytical validation and clinical implications of introducing a chromogranin A referral service within Scotland
    
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  - Could this be the tip of the iceberg? Endocrine dysfunction of immune checkpoint inhibitors in Kent Regional Oncology Service
    
    ea0059p115
  - TNF[alpha] regulates oestrogen uptake and metabolism in colorectal cancer
    
    ea0059p116
  - Epigenetic inhibitor treatment reduces proliferation via induction of apoptosis in a human typical bronchial carcinoid cell line
    
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  - The expression pattern of miR-16 in plasma of breast cancer patients attending radiotherapy clinic in luth
    
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  - Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival
    
    ea0059p119
  - Progestins used in menopausal hormone therapy is not a 'one-size-fits-all' for breast cancer risk
    
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  - Progestin-induced breast cancer: Identifying the role of progesterone receptor isoforms
    
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  - The human oestrogen receptor beta variant 5 (ERsz5) can alter the oestrogen sensitivity of oestrogen receptor alpha positive endometrial cancer cells
    
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  - ELL2 and EAF2 co-regulation of AKT in prostate cancer cells
    
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- Neuroendocrinology and pituitary
- - A single bolus of the novel kisspeptin analogue, MVT-602, induces a prolonged LH surge compared to kisspeptin-54 during the follicular phase in healthy women
    
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  - Anti-POMC siRNA reduces ACTH secretion in an in vitro model of Cushing's disease
    
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  - Natural history of conservatively managed Rathke's cysts: a retrospective analysis of a single centre experience
    
    ea0059p126
  - Identifying disease causing variants in aryl hydrocarbon receptor-interacting protein (AIP) variants and their significance on the clinical phenotypes
    
    ea0059p127
  - Are silent corticotroph adenomas high risk tumours for recurrence? Systematic review and meta-analysis
    
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  - The Utility of the high dose Short Synacthen test in pituitary patients who failed the ITT but have a low pre-test likelihood of ACTH deficiency
    
    ea0059p129
  - Measuring of information transfer via gonadotropin-releasing hormone receptors (GnRHR) shows a remarkable loss of information through signalling
    
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  - The importance of achieving disease control in Acromegaly: a retrospective single centre analysis
    
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  - Cannulated prolactin is useful to confirm hyperprolactinemia and to minimize inappropriate imaging
    
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  - Characterisation of paediatric craniopharyngiomas in a single centre study - analysis of factors affecting recurrence rates
    
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  - Prolactin as a surrogate marker of prolactinoma diagnosis in PCOS
    
    ea0059p134
  - Bolus 3% saline restores cognitive function more rapidly than traditional slow intravenous infusion of 3% saline in the emergency treatment of SIAD, with symptoms of cerebral irritation
    
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  - Recovery of the hypothalamic-pituitary-adrenal and thyroid axes up to 12 months following trans-sphenoidal adenomectomy
    
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  - Safety of prescribing for inpatients with cranial diabetes insipidus (CDI): a Southwest Peninsula Audit
    
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  - Outcomes of bilateral adrenalectomy in ACTH-dependent Cushing's syndrome
    
    ea0059p138
  - Postoperative metabolic profile of patients after pituitary surgery
    
    ea0059p139
  - Metoclopramide Test: Time for a revival in patients without classic symptoms and mild hyperprolactinaemia?
    
    ea0059p140
  - Active management of severe hyponatraemia by endocrinologists is associated with lower mortality
    
    ea0059p141
  - A single-centre audit of treatment outcomes in 185 acromegaly patients under regular follow-up
    
    ea0059p142
  - Prevalence of sinonasal mucosal disease before and after treatment of acromegaly
    
    ea0059p143
  - 25 years of sporadic insulinomas - A case series
    
    ea0059p144
  - Isoforms of the short chain alcohol dehydrogenase reductase enzyme 11[beta]HSD1L is differentially expressed in the pituitary, gonads and gastrointestinal tract
    
    ea0059p145
  - Role of Nurr1 in the regulation of Synaptogyrin 3 (SYNGR3)
    
    ea0059p146
  - Abstract unavailable
    
    ea0059p147
  - Investigation of gonadotroph ultrastructure secretory machinery in a novel mouse model of Patched1 deletion in folliculostellate cells
    
    ea0059p148
- Nursing practice
- - Assessement of Diabetes Distress in patients with diabetes mellitus taking insulin in a clinic in the United Arab Emirates
    
    ea0059p149
  - Nurse led parathyroid clinics - Improving the patient journey
    
    ea0059p150
  - The varied psychological support Acromegaly patients receive across the UK and what they believe can help improve their care; A patient perspective
    
    ea0059p151
  - Conducting research in vulnerable populations can be safe, beneficial and well received if infrastructure and staff experience are appropriate to patient's needs
    
    ea0059p152
- Obesity & metabolism
- - Subcutaneous adipose tissue from patients with Idiopathic Intracranial Hypertension exhibits metabolically distinctive characteristics
    
    ea0059p153
  - Dominant-negative mutations in PPAR alpha are present in unselected human populations and have a metabolic signature
    
    ea0059p154
  - Identity and cell fate of Ngn3-expressing population in small intestinal organoids
    
    ea0059p155
  - Randomised trial of empagliflozin versus metformin in polycystic ovary syndrome
    
    ea0059p156
  - The impact of lipopolysaccharide on mitochondrial efficiency in brown adipocytes
    
    ea0059p157
  - Increased pro-inflammatory cytokine production in vitamin B12 deficient adipocytes
    
    ea0059p158
  - Vitamin B12 deficiency leads to adipocyte dysfunction by enhancing triglyceride biosynthesis and impairing fatty-acid oxidation: a new protagonist in metabolic disease?
    
    ea0059p159
  - Screening for Cushing's syndrome in a tier 3 weight management service
    
    ea0059p160
  - B12 Receptors and transporters regulate the uptake and storage of vitamin B12 in hepatocytes
    
    ea0059p161
  - The relationship between obstructive sleep apnoea and quality of life in women with polycystic ovary syndrome: a cross-sectional study
    
    ea0059p162
  - Metformin treatment fails to restore fatty acid oxidation in low vitamin B12 hepatocytes
    
    ea0059p163
  - Prevalence of adenovirus 36 infection and association with obesity and diabetes in the United Arab Emirates
    
    ea0059p164
  - Obesity and diabetes in adults with down syndrome: data from a large diabetes centre in the United Arab Emirates (UAE)
    
    ea0059p165
  - Evaluating non-face to face (NFTF) contacts for patients with Thyrotoxicosis
    
    ea0059p166
  - Male 5-beta reductase knockout mice have altered pancreatic islet morphology and hormone secretion
    
    ea0059p167
  - The impact of freeze dried broccoli extract to mitigate inflammation in human adipocytes through the mevalonate pathway
    
    ea0059p168
  - Angiopoietin-like ptotein 4 and 8 (ANGPTL4 and ANGPTL8) in human fetal liver are dysregulated by in utero exposure to maternal smoking
    
    ea0059p169
  - Effects of visfatin on brown adipose tissue energy regulation
    
    ea0059p170
  - Glucocorticoid-induced metabolic syndrome: establishing the role of AgRP
    
    ea0059p171
  - Reduced PTEN levels enhance the proliferation as well as differentiation of preadipocytes
    
    ea0059p172
  - Fructose is metabolised by human subcutaneous adipocytes and can be used as a substrate for de novo lipogenesis
    
    ea0059p173
  - Placental DNA methylation is associated with infant adiposity but is not altered with metformin exposure
    
    ea0059p174
  - Hepatic Cyp17a1 regulates the adaptive starvation response aia a nuclear receptor network
    
    ea0059p175
  - A Direct Comparison of Metabolic Responses to NAD repletion in C57BL/6J and C57BL/6N diet-induced obesity mouse models
    
    ea0059p176
- Reproduction
- - Naringenin inhibits progression, proliferation and induces apoptosis via ROS generation in endometriotic lesions in rats
    
    ea0059p177
  - Altered vascular function in boys with hypospadias- role of reactive oxygen species
    
    ea0059p178
  - The effectiveness of management of pregnant women with type 1 diabetes mellitus with continuous subcutaneous insulin infusion
    
    ea0059p179
  - Aortic growth in Turner syndrome is accellerated compared with general population
    
    ea0059p180
  - Gonadectomy for adults with DSD conditions at risk of hypogonadism in the international disorders of sex development registry
    
    ea0059p181
  - Elongated transverse aortic arch in Turner syndrome: a useful marker for cardiovascular risk?
    
    ea0059p182
  - Impact of ethnicity on the change in total testosterone, haematocrit and prostate-specific antigen with Testosterone undecanoate treatment
    
    ea0059p183
  - Where Are They Now? Review of patients diagnosed with Disorders of Sex Development since 1988
    
    ea0059p184
  - Managment of women with premature ovarian insufficiency: a multi-disciplinary review of practice
    
    ea0059p185
  - Hormone replacement therapy and cognition in menopause
    
    ea0059p186
  - A prospective study of testicular development and function in boys with Duchenne Muscular Dystrophy
    
    ea0059p187
  - The impact of testosterone level on body composition in men with type 2 diabetes (T2D)
    
    ea0059p188
  - From Evidence to Practice, group education as part of routine outpatient clinic in Polycystic Ovary Syndrome a proof of concept intervention
    
    ea0059p189
  - Clomiphene citrate treatment in women with hypothalamic amenorrhea
    
    ea0059p190
  - Reproductive function in women after kidney transplantation
    
    ea0059p191
  - Alteration to PGF and IGF-1, signalled the adverse growth of the foetus and placenta in a genistein exposed pregnancy in experimental rats
    
    ea0059p192
  - Anti-fertility effect of aqueous seed extract of Buchholzia Coriacea
    
    ea0059p193
  - Investigating the roles of steroids in gonadal development and maintenance using an androgen and cortisol deficient zebrafish model
    
    ea0059p194
  - Exhaustive characterization of placental production of progesterone in vitro
    
    ea0059p195
  - Alterations in some heavy metal levels correlated with cellular adenosine triphosphate production in male rats exposed to a municipal dumpsite
    
    ea0059p196
  - Reproductive Life Course Project: Preliminary data from UK Turner Syndrome Pregnancy audit
    
    ea0059p197
  - Dax1 controls female fertility as a hypothalamic rheostat of estrogen receptor-alpha
    
    ea0059p198
  - Recombinant FSH dosing during controlled ovarian stimulation in IVF treatment
    
    ea0059p199
- Thyroid
- - Controlled Antenatal Thyroid Screening (CATS) II: long-term cardiometabolic effects of treating maternal sub-optimal thyroid function
    
    ea0059p200
  - Targeted sequencing of dyshormonogenesis-associated genes in Macedonian cases with congenital hypothyroidism and gland-in-situ reveals a low mutation frequency
    
    ea0059p201
  - Rate of progression of subclinical hypothyroidism to overt hypothyroidism: a 10-year retrospective study from UAE
    
    ea0059p202
  - Characterization of thyroid nodules in acromegalic patients
    
    ea0059p203
  - Evaluation of the Mental Health and Quality of Life of patients with hyperthyroidism attending an Endocrine Clinic
    
    ea0059p204
  - A second course of antithyroid drug therapy is effective in patients with relapsed Graves' disease
    
    ea0059p205
  - Iodine restricted diet prior to radioiodine therapy for hyperthyroidism
    
    ea0059p206
  - Can we predict relapse of Graves' disease after antithyroid drug therapy?
    
    ea0059p207
  - Clinico-pathological correlation of U3 thyroid nodules: A retrospective review
    
    ea0059p208
  - Low dose rituximab for thyroid eye disease: an effective treatment with fall in TSH receptor antibodies (TRAb)
    
    ea0059p209
  - Weight gain with hyperthyroidism therapy: a prospective pilot study
    
    ea0059p210
  - Ultrasonographic features and management of thyroid nodules undergoing ultrasound-guided fine needle aspiration
    
    ea0059p211
  - Low Dose Radioiodine Therapy for Graves' disease: comparison of outcomes following administration of different doses across two centres
    
    ea0059p212
  - Outcomes following radioactive iodine therapy (RAI) in hyperthyroid patients with Grave's disease and toxic nodular disease
    
    ea0059p213
  - Evaluation of a high sensitivity thyroglobulin assay for use in patients following total thyroidectomy and radioiodine ablation treatment
    
    ea0059p214
  - Utility of fetal thyroid scanning in pregnancy: experience in a single centre
    
    ea0059p215
  - Management of 'Anomalous' thyroid results
    
    ea0059p216
  - The use of a thyroid telephone clinic (TTC) to follow up thyroid function tests (TFTs) in patients treated with radio-iodine (RAI) for thyrotoxicosis
    
    ea0059p217
  - Abstract unavailable
    
    ea0059p217 (1)
  - Early and more frequent monitoring of thyroid function tests (TFTs) post RAI could be clinically beneficial
    
    ea0059p218
  - Improvements in monitoring and biochemical control of hypothyroidism in primary care with the use of an electronic protocol: 12-month follow up evaluation
    
    ea0059p219
  - Radioiodine therapy in benign thyroid disease
    
    ea0059p220
  - A retrospective study of outcomes of radioiodine treatment for benign thyroid disease
    
    ea0059p221
  - Assessment of efficacy with radioiodine treatment in Benign Hyperthyroid disease across two centres
    
    ea0059p222
  - Assessment of plasma sodium and potassium levels in sudanese patients with hypothyroidism
    
    ea0059p223
  - Identification of novel sodium iodide symporter (NIS) interactors which modulate radioiodine uptake
    
    ea0059p224
  - Using lightsheet microscopy to explore the relationship between NIS and its functional interactors ARF4, VCP and PBF
    
    ea0059p225
ePoster Presentations
- Adrenal and steroids
- - A rare erythropoietin secreting adrenal adenoma
    
    ea0059ep1
  - Testicular adrenal rest tumours masquerading as Leydig cell tumours in a 55-year-old man with congenital adrenal hyperplasia
    
    ea0059ep2
  - An atypical case of non-classical congenital adrenal hyperplasia
    
    ea0059ep3
  - Adrenal lymphoma: unusual presentation with unilateral mass and hypoadrenalism
    
    ea0059ep4
  - What lies beneath? Herbal medications can lead to adrenal insufficiency
    
    ea0059ep5
  - How reliable are regular menses as a guide to endocrine health?
    
    ea0059ep6
  - Pheochromocytoma mimicking sepsis
    
    ea0059ep7
  - Metastatic adrenocortical carcinoma: A Case Report
    
    ea0059ep8
  - Delayed diagnosis of Addison's disease and Autoimmune Polyglandular Syndrome Type 2 due to misinterpretation of short synacthen test
    
    ea0059ep9
  - Unusual size presents with unusual presentation
    
    ea0059ep10
  - Glucagon Stimulation test (GST) is superior to Short Synacthen test (SST) in diagnosing Adrenal insufficiency
    
    ea0059ep11
  - Loperamide induced hypoadrenalism presenting as recurrent hypoglycaemia in a patient with type 1 diabetes
    
    ea0059ep12
  - A rare cause of unexpected bilateral adrenal gland abnormalities
    
    ea0059ep13
  - Cushing's syndrome due to primary bilateral macronodular adrenal hyperplasia (PBMAH) - clinical and hormonal characterisation
    
    ea0059ep14
  - Intermittent primary aldosteronism - another hurdle in the Conn's story?
    
    ea0059ep15
  - Two cases of Addison's disease in pregnancy
    
    ea0059ep16
  - An unusual presentation of Cushing's syndrome
    
    ea0059ep17
  - Transient hypocortisolaemia in an HIV positive patient
    
    ea0059ep18
  - A case of challenging post-operative management in adrenal Cushing's syndrome
    
    ea0059ep19
- Bone and calcium
- Clinical biochemistry
- Clinical practice, governance & case reports
- Diabetes & cadiovascular
- - Multiple insulin allergies in a patient with diabetes
    
    ea0059ep63
  - Pneumomediastinum in diabetic ketoacidosis: an ominous sign?
    
    ea0059ep64
  - Treating salt before sugar
    
    ea0059ep65
- Neoplasia, cancer & late effects
- - Rapid onset hirsuitism in a post menopausal woman with an ovarian cyst
    
    ea0059ep66
  - Erythrocytosis caused by Vandetanib treatment in metastatic medullary thyroid carcinoma: the first case report
    
    ea0059ep67
  - IGF2 related non-islet cell tumour hypoglycaemia in a patient with hepatic sarcoma
    
    ea0059ep68
  - An unusual case of hypoglycaemia
    
    ea0059ep69
  - MEN 2A - a rare syndrome with variable intrafamilial gene expressivity, case presentation
    
    ea0059ep70
- Neuroendocrinology and pituitary
- Reproduction
- - An Unusual but Important Cause of Hyperandrogenism in Women
    
    ea0059ep88
  - From Antipsychotic-related Hyperprolactinemia to Klinefelter Syndrome: Taking the Patient as a Whole
    
    ea0059ep89
  - A rare case of primary hypogonadism and partial hypopituitarism in klinefelter syndrome
    
    ea0059ep90
  - An unusual case of hirsutism, baldness and ovarian leiomyoma
    
    ea0059ep91
  - A rare case of bilateral testicular epidermoid cysts in a patient with Klinefelter's syndrome
    
    ea0059ep92
  - The challenge of diagnosing 5-alpha-reductase deficiency post gonadectomy
    
    ea0059ep93
  - Pubertal arrest and hypoplastic reproductive organs in a 22-year-old female with a prolactinoma
    
    ea0059ep94
  - Localisation Challenges in Postmenopausal Hyperandrogenism
    
    ea0059ep95
  - Unusual Cause of Severe Hyponatraemia
    
    ea0059ep96
- Thyroid
Featured Clinical Cases
- Featured Clinical Cases

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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Endocrine Abstracts

Society for Endocrinology BES 2018

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