Endocrine Abstracts

We all live in an oscillating environment driven by the Earth’s rotation. This imposes predictable patterns of light and dark, to which almost all of life responds. There is a survival advantage in anticipating such environmental change, which has led to evolution of the autonomous circadian clock.The circadian clock controls up to 40% of biochemical pathways, often acting to control a rate-limiting enzymatic step. Therefore, design and interpretati...