Endocrine Abstracts

The cause of intrauterine growth restriction (IUGR) with abnormal umbilical artery (UA) Doppler indices is unknown. Previous studies indicate rearrangement of placental villi occur in IUGR pregnancies, disturbing normal blood flow to the developing fetus. Vasculature integrity is regulated by a variety of factors, including inflammatory cytokines. Inflammatory factors interleukin 6 (IL6), IL8, and CCL2 have been implicated in abnormal placental structure and function in pre-ec...

Background: Inflammatory cytokines were considered to play a determinant role in the development and progression of different microvascular diabetic complications including diabetic retinopathy. interleukin 27 (IL27) is a cytokine with dual proinflammatory/anti-inflammatory effects that mediates pathogenesis of different inflammatory diseases.Aim: To assess the serum and aqueous levels of (IL27) as proinflammatory/anti-inflammatory cytokine in diabetic p...