ea0025pl4 | Society for Endocrinology European Medal Lecture 2010 | SFEBES2011
Allolio Bruno
Adrenocortical carcinoma (ACC) is a heterogeneous neoplasm with an incompletely understood pathogenesis and an unsatisfactory prognosis. However, international initiatives like the European Network for the Study of Adrenal Tumours (ENSAT) and international trial consortia recently led to improved diagnosis and treatment. Activated signalling pathways primarily involved in adrenal development like IGF2, SF1, and β-catenin pathways play also a key role in the ACC developmen...