Endocrine Abstracts

Treatment of gender dysphoric individuals, has in medicine nearly always met with a great deal of skepticism. In recent years, changes in the clinical management of adolescents have been made by clinicians in Europe and North America. In their clinics, puberty is suppressed in an early pubertal stage and/or at certain ages. The clinicians have come to this decision for various reasons: 1) the adverse effects of a relatively late treatment start on the adolescents’ psychol...

The Endocrine Society has published guidelines on the endocrine treatment of transsexual persons (J Clin Endocrinol Metab 2009 94 3132–54). For adolescents with gender identity disorder (GID), the guideline recommends that suppression of pubertal hormones start when girls and boys exhibit physical changes of puberty (confirmed by pubertal levels of estradiol and testosterone, respectively), but no earlier than Tanner stages 2–3. In practice, this...