Endocrine Abstracts

Prolactinomas usually present because of reproductive/sexual dysfunction due to the hyperprolactinemia but they may also present because of mass effects. Prolactin (PRL)-secreting microadenomas enlarge in only about 7% of cases, so many can be followed without direct treatment, although sex steroid hormone replacement may be required. Dopamine agonists can normalize PRL levels in over 90% of cases and can reduce tumor size significantly in over 75%, with cabergoline being gene...

Mark E Molitch, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA AbstractMark E. Molitch, MD, is Professor of Medicine and a Member of the Division of Endocrinology, Metabolism and Molecular Medicine at Northwestern University Feinberg School of Medicine, in Chicago, Illinois. Prior to joining the faculty at Northwestern in 1984, Dr. Molitch was an Associate Professor at Tufts University School of...