Endocrine Abstracts

Contents

• Plenary Lectures' Biographical Notes
• • Society for Endocrinology Jubilee Medal Lecture
  • • Per ardua ad pituita: not just phlegm

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    • Society for Endocrinology Jubilee Medal Lecture

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  • Society for Endocrinology Dale Medal Lecture
  • • Healthspan: how far can it be extended into aging?

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    • Society for Endocrinology Dale Medal lecture

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  • Society for Endocrinology Transatlantic Medal Lecture
  • • Estrogen action: two decades of humbling predictions

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    • Society for Endocrinology Transatlantic Medal Lecture

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  • Society for Endocrinology European Medal Lecture
  • • Early stages of thyroid autoimmunity

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    • Society for Endocrinology European Medal Lecture

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  • Society for Endocrinology International Medal Lecture
  • • Hormones and behaviour: new insights from GFP molecular imaging and neuroanatomy

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    • Society for Endocrinology International Medal Lecture

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  • The British Thyroid Association Pitt-Rivers Lecture
  • • A 30-year perspective on radioiodine therapy for nontoxic goitre: from non-acceptance to implementation of recombinant human TSH (rhTSH)-augmented therapy

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    • The British Thyroid Association Pitt-Rivers Lecture

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  • Clinical Endocrinology Trust Visiting Professor Lecture
  • • What have we learned about the management of patients with prolactinomas?

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    • Clinical Endocrinology Trust Visiting Professor Lecture

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  • Society for Endocrinology Medal Lecture
  • • New genes, new diabetes and new treatments

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    • Society for Endocrinololgy Medal Lecture

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  • Clinical Endocrinology Trust Lecture
  • • The metabolic consequences of pituitary insufficiency

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    • Clinical Endocrinology Trust Lecture

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• Symposia
• • Finding the right balance of dietary and metabolic influences in fetal and adult life
  • • Chronic stress, glucocorticoids, insulin and obesity

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    • Transgenerational effects of glucocorticoid programming

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    • Consequences of unbalanced maternal nutrition

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    • The fetal cost of maternal cafeteria diets

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  • Calcium conundrums: too high, too low and what to do
  • • Management of severe hypercalcaemia

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    • Diagnosis and management of post-operative hypocalcaemia following (para)thyroidectomy

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    • Familial benign hypocalciuric hypercalcaemia - an update

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    • Mild hyperparathyroidism: to treat or not to treat, that is the question

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  • What's Wnt? A novel signalling pathway in endocrinology
  • • Wnt signaling in adrenal stem/progenitor cells: implications for organ homeostasis and cancer

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    • Targeting mediators of Wnt signalling by GnRH

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    • Defects in Wnt signalling in hyperparathyroidism

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    • Paracrine signalling in the ovary: the role of Wnt

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  • What is the TSH set point? Does it matter?
  • • Physiological determination of the hypothalamic pituitary thyroid axis set point

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    • Genetic determinants of the HPT axis set point

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    • Abnormalities of the HPT axis - lessons from paediatric endocrinology

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    • Pathological consequences of altered HPT axis set-point: subclinical thyroid disease?

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  • The endoplasmic reticulum – an important link between inflammation, stress and metabolism
  • • The role of the unfolded protein response in [beta] cell function

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    • Endoplasmic reticulum stress and hepatic lipid metabolism

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    • The endoplasmic reticulum as a metabolic compartment

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    • Glucose sensing in the endoplasmic reticulum: maintaining the cellular environment

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  • Polycystic ovarian syndrome (PCOS): when does it start, why and what to do about it?
  • • Searching for genes in polycystic ovary syndrome

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    • Evolution of obesity and insulin resistance: relevance to PCOS

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    • The teenager with polycystic ovarian syndrome (PCOS)

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    • Metformin-a storm with few good data

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  • Phosphoinositide 3-kinase (PI3K) signalling in health and disease: an old system with new potential
  • • Signalling from cell surface receptors: molecular mechanisms and physiological significance of the phosphoinositide 3-kinase signalling system

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    • Disordered phosphoinositide signalling and the basis of tumour formation

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    • Regulation of hepatic lipid metabolism by insulin

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    • PI3 kinase inhibitory drugs: fantasy or reality?

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  • Novel aspects of bone physiology in relation to osteoporosis treatment
  • • New tools for the study of bone-active drugs

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    • Bone signalling pathways - their importance in the treatment of osteoporosis

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    • Anabolic therapy for osteoporosis

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    • Uses and abuses of bisphosphonates

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  • Kisspeptin: a novel regulator of puberty and fertility
  • • Kisspeptin signalling and fertility

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    • Role of kisspeptin in the metabolic regulation of fertility

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    • Human kisspeptin receptor mutations and puberty

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    • What does kisspeptin do in humans?

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• Clinical Management Workshops
• • Measuring hormones: what does your result mean
  • • What service does the laboratory provide?

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    • Is what is normal for me normal for you?

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    • What new tests are on the horizon?

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    • Interpreting results: a Clinician's perspective

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  • Improving mortality and morbidity in pituitary disease
  • • Mortality in patients with pituitary disease

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    • Does hormone replacement normalise life expectancy?

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    • Why craniopharyngioma remains a condition with a high mortality and morbidity?

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    • Adverse outcomes following pituitary radiotherapy

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  • Endocrine consequences of cancer treatment
  • • Survivorship following cancer: an overview

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    • Gonadal function and fertility potential

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    • Endocrine consequences of cancer treatment: pituitary and thyroid dysfunction: who gets it, when to test and how?

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    • Survivorship and models of care for endocrinologists

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  • Interfaces between endocrinology and internal medicine
  • • Amiodarone-associated hyperthyroidism, a practical guide to investigation and therapy

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    • Epilepsy in women: endocrine, metabolic and reproductive health considerations caring for the woman with epilepsy

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    • Iatrogenic adrenal suppression: diagnosis and management

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    • Hyponatraemia: investigation and management

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• Nurses' Session
• • Sex hormone replacement
  • • Hormone replacement therapy

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    • HRT case presentation: gonadal dysgenesis

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    • When HRT causes a headache

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    • Recent advances in male hypogonadism

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    • Androgen replacement in female to male transgender

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  • Thyroid disease
  • • Thyroid hormone replacement

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    • Raised TSH: hypothyroidism, poor compliance or what?

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    • Congenital hypothyroidism

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    • Autoimmune thyroid disease with subsequent biochemical abnormalities and pregnancy

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• Young Endocrinologists Sessions
• • Young Endocrinologist prize lecture
  • • In search of the genetic basis of polycystic ovary syndrome and its metabolic consequences

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    • An anti-inflammatory role of interleukin-4 in the human ovarian surface epithelium

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  • The ‘how to’ guide on scientific communication
  • • How to write a scientific paper

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    • Conference presentations: how to engage your audience

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    • Poster presentations: from poster layout to data presentation

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    • Scientific networking: how to make the most of networking opportunities

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• Applied Physiology Workshop
• • (1)
  • • Characterising over consumption: appetite expression and food choice

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    • The limitations of DXA for body composition assessment

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    • The hyperinsulinaemic euglycaemic clamp and stable isotope methodology for in vivo physiological studies

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    • Magnetic resonance spectroscopy: a window into carbohydrate and lipid metabolism

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• Retired Endocrinologists' Session
• • (1)
  • • What is the point of the adrenal cortex?

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    • Importance of comparative studies to general understanding of endocrine systems

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    • Photoperiodic signalling in birds

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    • Anabolic steroid abuse in the gym

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    • Leadership for creation of excellence

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    • Jade, sex and a Chinese neolithic culture

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• Oral Communications
• • Young Endocrinologist prize session
  • • Alternative splicing of the thyroid hormone receptor [alpha] gene regulates skeletal development

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    • Anti-inflammatory effects of 5 alpha-reduced glucocorticoids in vitro and in vivo

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    • The role of gucocorticoid metabolism in osteosarcoma pathogenesis and treatment

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    • Kisspeptin potently increases reproductive hormone release in women with hypothalamic amenorrhoea: a potential novel therapy for infertility

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    • Selective inhibition of 11[beta]-hydroxysteroid dehydrogenase type 1 improves insulin sensitivity in skeletal muscle through modulation of IRS1 serine phosphorylation

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    • Locally generated glucocorticoids, rather than pro-inflammatory cytokines, directly regulate synovial DKK-1 expression in inflammatory arthritis

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    • In vivo and ex vivo regulation of Visfatin production by leptin in human and murine adipose tissue: role of the PI3K and MAPK pathways

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    • Quality of life (QoL) in male and female patients with congenital adrenal hyperplasia (CAH) compared to healthy subjects and patients with primary adrenal insufficiency

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  • Neuroendocrine and Steroids
  • • 11[beta]-hydroxysteroid dehydrogenase type 1 activity limits fibrosis following bleomycin lung injury by augmenting active glucocorticoids

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    • PAPSS2 deficiency: a novel monogenic cause of androgen excess

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    • Familial and phenotypic associations of the aldosterone renin ratio in the general population

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    • Absence of hexose-6-phosphate dehydrogenase specifically induces skeletal myopathy in mice

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    • Inhibition of 11[beta]-hydroxysteroid dehydrogenase type 1 promotes intra-retinal vascularisation in a murine model of ischaemic retinopathy

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    • Urinary steroid profiling as a biomarker tool for the detection of adrenal malignancy: results of the EURINE ACC Study

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    • Identification of the gene for FGD type 3 on chromosome 8

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    • Immunohistochemical evidence that Argillin, the product of the ECRG4 gene, encodes a novel neuroendocrine peptide

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  • Cardiovascular metabolism
  • • Effect of single high vs low glycemic index (GI) meal on gut hormones

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    • Non alcoholic fatty liver disease is associated with increased 5[alpha]-reductase expression and activity and consequent HPA-axis activation

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    • Glucocorticoid and insulin regulation of lipogenesis in human adipose tissue

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    • The novel peptide prokineticin-2 potently inhibits food intake in rodents and is a potential novel anti-obesity therapy

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    • Cerebellin1 is a novel orexigenic factor which potently increases food intake via hypothalamic neuropeptide Y release

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    • The effects of ghrelin and cannabinoids on AMP-activated protein kinase (AMPK) activity in growth hormone-secretagogue receptor (GHS-R) knockout mice

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    • Insulin increases and metformin decreases the novel adipokine chemerin in insulin resistant subjects: PCOS as a paradigm

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    • Metformin improves arterial stiffness and endothelial function in young women with PCOS: a randomised, crossover trial

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  • Bone and Calcium
  • • Genome-wide abnormalities in parental inheritance patterns and DNA methylation in Russell-Silver syndrome

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    • Primary hyperparathyroidism (Nationwide Cohort Study): an increased risk of cancer and decreased survival

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    • Adipokines may modify osteoblast wnt-signalling through dickkopf-1, and promote osteoclastogenesis by altering RANK-L and osteoprotegerin signalling in obese children

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    • Novel Glial Cells Missing B (GCMB) mutations (Arg39Stop and Arg110Trp) that result in loss of subcellular localization and DNA binding, respectively, are associated with autosomal recessive hypoparathyroidism

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    • Nuf mice with an activating calcium sensing receptor mutation, Leu723Gln, have hypercalciuria and diabetes insipidus

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    • Mice deleted for the hyperparathyroidism-jaw tumour (HPT-JT) syndrome allele have abnormal parathyroids with increased proliferation rates

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    • A mouse with a Trp589Arg mutation in N-acetylgalactosaminyltransferase 3 (Galnt3) provides a model for familial tumoural calcinosis

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    • Human primary cytotrophoblasts from normal and IUGR pregnancies respond differently to T3 treatment in vitro

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  • Thyroid, reproduction and endocrine tumours
  • • Thyrotropin receptor (TSHR) activation increases hyaluronan (HA) production in preadipocyte-fibroblasts; explanation for HA accumulation in thyroid dysfunction?

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    • Reduction of type I 5[prime]-iodothyronine deiodinase activity and mRNA level in renal clear cell carcinoma (ccRCC): potential role of 3[prime] UTR and miRNA

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    • Bio-informatic identification of novel endocrine markers of gestational disease in the human placenta

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    • Spatio-temporal expression of bone morphogenetic protein (BMP) antagonists during early follicle development

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    • Elderly patients presenting with hyperthyroidism have a paucity of symptoms and signs: a cross-sectional study of 3563 UK patients

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    • Bone morphogenetic protein-2 and -4 enhance FSH-induced p38 activation leading to upregulation of estradiol production through oocyte-granulosa cell interaction

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    • Contrasting clinical manifestations of SDH-B and VHL associated chromaffin tumours

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    • The clinical and genetic characteristics of patients with familial isolated pituitary adenoma

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• Poster Presentations
• • Bone
  • • Project sunshine - is there a seasonal variation in bone mineral density? a retrospective study

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    • A ten-year epidemiological study of prevalence and incidence of primary hyperparathyroidism in Tayside, Scotland

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    • Bone parameters and body composition in paediatric renal patients in the year following transplantation

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    • Effects of five gut hormones on osteoblastic-like cell lines

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    • Identification of a kindred from Northern Ireland with familial hypocalciuric hypercalcaemia type 3, which maps to chromosome 19q13.3

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    • A Ser1386Pro mutation in the C-propeptide domain of Col2a1 results in spondyloepiphyseal dysplasia congenita in mice

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    • A mouse model, Hcalc1, for autosomal dominant hypercalciuria is due to a transient receptor potential cation channel, subfamily V, member 5 (Trpv5) mutation

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    • The potential inhibitory role of SOCS2 in chondrocyte GH/IGF-1 signalling during chronic inflammatory diseases

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    • Effects of adiponectin on the osteosarcoma cell line Saos-2

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    • Bone mineral density and body composition in adult men and women with CAH hyperplasia: congenital adrenal hyperplasia adult study executive

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    • Impact of body mass index at baseline on parathyroid hormone and phospho-calcium metabolism in adult growth hormone deficient patients before and after growth hormone replacement therapy

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    • Mesenchymal stem cell differentiation to osteoblasts and adipocytes is associated with differential adenosine receptor expression

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    • Hyperparathyroidism secondary to a parathyroid carcinoma

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    • Osteoporosis as a major risk for patients with glycogen storage disease

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    • Novel mutation of the COL1A2 gene in a patient with osteogenesis imperfecta

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    • Familial hypocalciuric hypercalcaemia and pregnancy outcome

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    • Determinants of vitamin D deficiency in chronic pancreatitis

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    • Renal bone disease control: comparison between diabetics and non diabetics in 187 haemodialysis patients

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    • Primary hyperparathyroidism: osteopaenia and osteoporosis

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    • A case of severe hyperparathyroidism with brown tumour and vitamin D deficiency- treated as simple bone cyst

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    • Activation of AMP-activated protein kinase represses chondrocyte proliferation

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  • Clinical practice/governance and case reports
  • • 'Health supplements' - not always good for your health!

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    • An unusual case of SIADH precipitated by chronic inflammatory demyelinating polyneuropathy

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    • All that glitters (on a bone scan) is not cancer

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    • Prevalence and identification of vitamin D deficiency in a falls population

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    • Use and monitoring of testosterone replacement therapy at a district general hospital

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    • The utility of routine biochemistry in detecting vitamin D deficiency in South Asians with and without type 2 diabetes

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    • Hyperglycaemia in a patient with pheochromocytoma

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    • Screening for Cushing's syndrome using the 1 mg overnight dexamethasone suppression test

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    • Bilateral testicular adrenal rests in congenital adrenal hyperplasia

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    • Bisphosphonate-induced hypocalcaemia on patient with malignancy induced hypercalcaemia

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    • Abstract unavailable

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    • Hypomagnesaemia and associated electrolyte abnormalities

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    • Primary hyperparathyroidism: dual localisation to improve cure rate

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    • Recombinant human growth hormone in pregnancy

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    • Carbimazole-induced myositis: a rare but significant adverse reaction

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    • Autosomal dominant familial cranial diabetes insipidus

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    • A mysterious case of postmenopausal hyperandrogenaemia

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    • Use of testosterone undecanoate 1000 mg (Nebido) injections to induce puberty in 2 men with Kallmann's syndrome presenting in their 6th decade

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    • Prevalence of cardiovascular risk factors and related characteristics in women with polycystic ovarian syndrome

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    • Retrospective analysis of subfertility, hormonal profile and radiological features in women with polycystic syndrome on presentation

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    • Delayed presentation of pituitary apoplexy as adrenal crisis in a man with vitiligo

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    • Unusual presentation of non - PTH dependant hypercalcaemia

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    • Lessons from a case of pituitary thyrotrophinoma I: not all TSH-omas are macroadenomas II: thyroid autoimmunity can be associated III: associated central hyperthyroidism can be subclinical

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    • Total serum cortisol, free cortisol index and salivary cortisol in monitoring oral hydrocortisone replacement

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    • Non-identical Kallmann's syndrome in otherwise identical twins

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    • A case of a disappearing adrenal mass with raised urine catecholamines

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    • Multiple endocrinal disorders and nephrotic syndrome in a patient with covert lung cancer

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    • Prepubertal gynaecomastia due to aromatase excess syndrome - novel allele presence in CYP19A1 gene

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    • Hypomagnesaemia and hypocalcaemia with proton-pump inhibitors: an under-recognised phenomenon

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    • Intestinal neurofibromatosis and subclinical Cushing's syndrome

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    • A hypokalaemia of all sorts

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    • Lithium associated hyperparathyroidism: when to investigate?

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    • Tertiary hyperparathyroidism in pregnant women with vitamin D deficiency

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    • Following a cardiac arrest in this seemingly healthy 28-year-old, all became clear

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    • Pituitary ACTH-dependent Cushing's syndrome caused by ectopic CRF secretion from an intra-adrenal phaeochromocytoma

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    • Hyponatraemia in primary care: not always due to inappropriate ADH!

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    • An interesting case of Turner syndrome with spontaneous pregnancies

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    • Cabergoline and cardiac valvulopathy - a unit review

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    • Non-classic congenital adrenal hyperplasia and the 18 week wait

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    • A case of hypopituitarism presenting as hyponatraemia

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    • Hypertensive crisis secondary to a germ cell tumour

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    • A rare case of hypercalciuria

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    • Thyroxine replacement precipitating adrenal crisis

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    • Prostate cancer- a rare cause of hypopituitarism

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    • Hyponatraemia- management dilemma

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    • Secondary ovarian failure in a patient with prolonged anorexia

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    • Generalised glucocorticoid resistance diagnosed by chance

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    • Diagnostic and therapeutic challenges in virilised female with learning difficulties

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    • A case of reversible pseudo-phaeochromocytoma

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    • Audit of a nurse-led thyroid telephone consulting service for the management of thyroid dysfunction

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    • Late onset congenital adrenal hyperplasia masquerading as subclinical Cushing's syndrome

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    • A case of macroprolactinoma associated with a giant carotid artery aneurysm

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    • Thiazolindinediones are useful in achieving female type fat distribution in male to female transsexuals

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    • Fronto-ethmoidal mucocele: a late complication of trans-ethmoidal pituitary surgery and a cause of unilateral proptosis in the endocrine clinic

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    • The 'new start' weight loss programme: developing and piloting a real world intervention for patients with severe morbid obesity

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    • Expansion of a VHL-associated spinal haemangioblastoma in pregnancy

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    • Managing hyponatraemia - a challenge

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    • Directly observed medication supplementation for non-compliance in a patient with hypothyroidism and hypoparathyroidism

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    • Are young people with congenital adrenal hyperplasia engaging with adult endocrine care?

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    • Acute myopathic paraparesis as the first manifestation of thyrotoxicosis

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    • Flucloxacillin induced hypokalaemia and hypomagnesaemia

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    • Screening for primary aldosteronism in a secondary care diabetes population

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    • New onset addison's disease presenting as prolonged hyperemesis in early pregnancy

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    • Assessing the impact of a fracture liaison service: a comparative audit of secondary prevention of osteoporosis in post-menopausal females treated in two fracture units, one with a fracture liaison service and one without

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    • A case of totally inappropriate administration of ADH

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    • Cinacalcet treatment to predict the results of parathyroidectomy: a report of two cases

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    • Quality of life in adult patients with congenital adrenal hyperplasia - results of the congenital adrenal hyperplasia adult study executive

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    • Transient secondary hypoadrenalism after a single intra-articular steroid injection-a case report

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    • On adequate thyroxine replacement and still symptomatic

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    • Dilemmas in the diagnosis of primary hyperaldosteronism

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    • A case of mistaken identity: metastatic thyroid follicular carcinoma masquerading as an incidental solitary pulmonary carcinoid lesion

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    • Near-normoglycemic remission in diabetic ketoacidosis: a case report

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    • Audit of investigation and management of adrenal incidentaloma

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    • An audit of thyroid surveillance in amiodarone treated subjects - room for improvement

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    • When is subclinical hypothyroidism just subclinical?

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    • Acute adrenal insufficiency due to bilateral adrenal haemorrhagic infarction in antiphospholipid syndrome

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    • Endocrine genes - have we improved the fit? (project development to service provision)

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    • Testosterone replacement therapy in Prader-Willi syndrome with diabetes markedly improves glycaemic control

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    • Iatrogenic Cushing's syndrome due to Kaletra and Seretide: learning points

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    • Severe obstructive sleep apnoea causing a pseudo-Cushing's state

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    • Propylthiouracil-induced antineutrophilic cytoplasmic antibody-positive vasculitis

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    • Idiopathic urticaria and angioedema in a patient with autoimmune thyrotoxicosis

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    • Recurrence of hyperthyroidism - 12 years after radioiodine induced hypothyroidism; a case report

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    • Acute presentation of Addison's disease with idiopathic intracranial hypertension in a young female

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    • The challenges of implementing consensus recommendations for GH therapy in GHD adolescent survivors of childhood cancer during the transition period

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    • A case of malignant paraganglionoma presenting as mass in the right clavicle

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    • Case of persistent mild hypocalcaemia? Carbamazepine induced osteomalacia

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  • Cytokines and growth factors
  • • Quantum dot labelled IGF-I: a novel technique to study IGF-signal transduction in the human placenta

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    • GnRH regulation of FoxO transcription factors

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    • Glucose does not influence placental regulation of insulin-like growth factor bioavailability during pregnancy

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    • Lack of short term catch up growth in children with Crohn's disease treated with infliximab

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    • Adipokines and their influence on blood pressure in young women

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    • Expression and purification of a potential long-acting leptin agonist

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  • Diabetes, Metabolism and Cardiovascular
  • • Clinically unapparent central nervous system impairment in diabetic patients

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    • The effects of combined plant derived oleanolic acid and insulin on blood glucose concentration in streptozotocin-induced diabetic rats

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    • Ileal switch with sleeve gastrectomy for control of type 2 diabetes

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    • Inverse correlation of fasting urine pH with body mass index in obese type 2 diabetes patients

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    • Effect of Metformin and a hypocaloric diet on lipids and their biological variation in polycystic ovarian syndrome

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    • Insulin resistance before and after parathyroidectomy in primary hyperparathyroidism

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    • Concentrations of matrix metalloproteinase 2 and 9 in patients with type 2 diabetes and in non-diabetic controls

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    • Effect of green coffee bean extract and chlorogenic acid consumption on 11[beta]HSD activity in humans and mice

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    • Expression of ghrelin O-acyltransferase (GOAT), the newly-identified ghrelin acylation enzyme, in various human tissues

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    • Renal effects of plant-derived oleanolic acid in streptozotocin-induced diabetic rats

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    • Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and insulin resistance on a high fat diet

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    • Visfatin regulates insulin secretion and insulin receptor phosphorylation in a clonal beta-cell line

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    • Glucocorticoid effects on the programming of AT1b angiotensin receptor expression in the rat fetus

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    • Napping is associated with an increased risk of the metabolic syndrome

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    • Muscarinic acetylcholine receptors and adipogenesis

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    • Withdrawal of proton-pump inhibitor (PPI) therapy in chronically hypomagnesaemic patients

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    • Identification of nesfatin-1/NUCB2 as a novel depot-specific adipokine in human and murine adipose tissue: aletered levels in obesity and food deprivation

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    • Effects of high fructose and salt intake on maternal metabolism and fetal development in rats

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    • Adrenal hypertrophy occurs in concert with insulin resistance following high fat feeding of two different strains of rat

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    • Downregulation of hepatic glucose 6-phosphatase-alpha in patients with nonalcoholic fatty liver

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    • Knockdown of H6PDH in C2C12 muscle cells impairs 11[beta]-HSD1 activity and myogenic differentiation

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    • Susceptibility to hyperinsulinaemia and fatty liver with loss of 5alpha-reductase 1 occurs in rats and mice and is not androgen dependent

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    • Sucralose ingestion does not elicit a GLP-1, PYY or appetite response in healthy, normal-weight volunteers.

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    • Libya has the highest prevalence of diabetes mellitus type 2 in North Africa and in the Arab world

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    • Effects of DHEA supplementation on vascular function in primary and secondary adrenal insufficiency: a randomised, crossover trial

      ea0019p139
    • Heterozygous knockout of the insulin-like growth factor 1 receptor in mice leads to impaired glucose tolerance, enhanced insulin sensitivity and increased endothelial basal nitric oxide production

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    • Epigenetic changes of the hypothalamic glucocorticoid receptor gene occur in the ovine foetus in conjunction with periconceptional undernutrition

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    • Periconceptional undernutrition is associated with epigenetic changes in the Proopiomelanocortin (POMC) gene in the hypothalamus of foetal sheep

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    • Increased mineralocorticoid activity in obese Zucker rats is independent of the renin-angiotensin system and hepatic steroid metabolism.

      ea0019p143
    • Screening for testosterone deficiency in a hospital diabetic clinic

      ea0019p144
    • Autocrine/paracrine regulation of visfatin induced MCP-1: enhanced pro-angiogeneic effects of visfatin in the human endothelium

      ea0019p145
    • Metformin decreases angiogenesis via ERK1/2/ERK5 pathways by increasing the anti-angiogenic adipokine thrombospondin-1

      ea0019p146
    • Effect of pre and postnatal diet on pancreatic beta-cell insulin and glucagon content

      ea0019p147
    • Extreme hypertriglyceridaemia, the therapeutic use of insulin

      ea0019p148
    • The Hsp90 chaperone machinery can modulate cell surface expression of the obesity linked G-protein coupled receptor MC4R

      ea0019p149
    • Kisspeptin inhibits key stages of angiogenesis in vitro

      ea0019p150
    • Body composition in HIV infected South Indian men

      ea0019p151
    • Insulin resistance, body composition and energy expenditure in young south indian males with normal and low birth weight

      ea0019p152
    • Metabolic syndrome in type 1 diabetes using IDF guidelines

      ea0019p153
    • Prevalence of eating disorder characteristics in the morbidly obese patients

      ea0019p154
    • 7-Oxysterols are metabolised by 11[beta]-hydroxysteroid dehydrogenase-1 within the aortic wall but do not directly influence contractility

      ea0019p155
    • Differences in hepatic fatty acid metabolism explain contrasting body weight and steatohepatitis in dietary models of non-alcoholic fatty liver disease in mice

      ea0019p156
    • The prevalence of erectile dysfunction and its socio-demographic and lifestyle correlates among male type 2 diabetics in Jos, Nigeria

      ea0019p157
    • Blood pressure control: comparison between non-diabetics and diabetics in 187 haemodialysis patients

      ea0019p158
    • Metformin attenuates hypoglycaemia secondary to dumping syndrome

      ea0019p159
    • Activating androgen receptor CAG and GGN polymorphisms and low total testosterone are associated with lower HDL cholesterol in men with type 2 diabetes

      ea0019p160
    • MMIF but not MCP-1 is correlated with adipose-derived TNF alpha in human obesity

      ea0019p161
    • Diabetic nephropathy: intense intervention or conventional care?

      ea0019p162
    • Abstract unavailable

      ea0019p162a
  • Endocrine tumours and neoplasia
  • • Relationships between 24-hour urine calcium:creatinine clearance ratio and fractional excretion of calcium based on fasting morning urine samples

      ea0019p163
    • Inhibitory effects of bone morphogenetic proteins on estrogen-induced proliferation of breast cancer cells

      ea0019p164
    • Adrenal insufficiency in post chemotherapy patients: an often missed diagnosis.

      ea0019p165
    • Hormonal activity of adrenal incidentalomas

      ea0019p166
    • Pheochromocytoma mimicking an acute coronary syndrome

      ea0019p167
    • Short-term and longer-term test-retest reliability of non-fasting calcium:creatinine ratio and fasting fractional excretion of calcium

      ea0019p168
    • Overexpression of human RAMP3 (receptor activity-modifying protein-3) in E. coli and mammalian cells

      ea0019p169
    • The influence of oestrogen on PBF expression, secretion and invasion in MCF7 cells

      ea0019p170
    • Asymptomatic children with multiple endocrine neoplasia type 1 (MEN1) mutations harbour pancreatic and pituitary tumours

      ea0019p171
    • Assessment of in vivo proliferation rates in parathyroid tumours of multiple endocrine neoplasia type 1 (MEN1) knockout mice: implications for evaluating the effectiveness of novel therapies.

      ea0019p172
    • Metastatic insulinoma with persistent hypoglycaemia

      ea0019p173
    • PBF-mediated alteration of sodium iodide symporter localisation and activity in differentiated thyroid cancer

      ea0019p174
    • A patient with neurofibromatosis type-1 (NF1) presenting with multiple endocrine neoplasia (MEN)2B

      ea0019p175
    • Adenosine A2 receptor signalling mediates chromogranin A secretion from neuroendocrine Tumours

      ea0019p176
    • A metastatic neuroendocrine tumour: diagnositic and therapeutic dilemmas

      ea0019p177
    • Is it an unusual variant of Multiple Endocrinal Neoplasia?

      ea0019p178
    • Probable recurrence of spontaneously resolved primary hyperparathyroidism

      ea0019p179
    • Abiraterone acetate: the novel application of a CYP450c17 inhibitor to the treatment of both prostate and breast cancer

      ea0019p180
    • Neuroendocrine gastric carcinoma and MEN 1: a novel mutation of MEN 1 gene

      ea0019p181
    • Phaechromocytoma presenting as myopathy

      ea0019p182
    • Successful pregnancies in active acromegaly

      ea0019p183
    • A case presentation: medical management of macroprolactinoma in a 16-year-old boy

      ea0019p184
    • The KL (klotho) gene is epigenetically silenced in primary hyperparathyroid tumours

      ea0019p185
    • Extracellular signal-regulated kinase pathway is over-activated in pituitary adenomas

      ea0019p186
    • Management of hypocalcaemia in pregnancy

      ea0019p187
    • Perioperative stabilization of hyperparathyroidism with cinacalcet

      ea0019p188
    • Genetics in mainstream medicine: best practice review

      ea0019p189
    • Expression of guanylyl cyclase-B (GC-B) receptors in a range of human pituitary adenomas: evidence for a local natriuretic peptide system

      ea0019p190
    • Partial remission of Nelson's syndrome after pituitary apoplexy during pregnancy

      ea0019p191
    • IL-1[alpha] regulation of steroid sulphatase (STS) enzyme activity and 17 [beta]-hydroxysteroid dehydrogenase 5(17 [beta]hsd5) gene expression in normal human ovarian surface epithelium (OSE), epithelial ovarian cancer (EOC) and cell lines

      ea0019p192
    • Von Hippel Lindau syndrome: a case report

      ea0019p193
    • Essential role of TRPC channels in human ovarian cancer cell proliferation

      ea0019p194
  • Growth and development
  • • Delayed puberty: an occult systemic cause

      ea0019p195
    • Abstract unavailable

      ea0019p196
    • Altered IGF-I signalling in children born small for gestational age without catch up growth

      ea0019p197
    • Maternal protein or energy restriction and offspring HPA axis response to an ITT

      ea0019p198
    • Characterisation of the nuclear localisation signal (NLS) site of GATA3

      ea0019p199
    • The influence of birth weight on glucocorticoid receptor (GR) and peroxisome proliferator activated receptor (PPAR)[alpha] gene expression and lipid content in liver from neonatal pigs

      ea0019p200
    • Monocarboxylate transporter 8 (MCT8) in human fetal central nervous system (CNS) development

      ea0019p201
    • Characterisation of a novel GATA3 mutation in hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome

      ea0019p202
    • Human fetal mesenchymal stem cells can differentiate into white and brown adipocytes, and reveal a role for ERR[alpaha] in human UCP1 expression

      ea0019p203
    • Influence of JAK2 and PI3kinase genotypes on growth response to growth hormone (GH) therapy

      ea0019p204
    • Exposure to a maternal dietary protein restriction during gestation impedes hepatoblast differentiation

      ea0019p205
    • Natural history of CHARGE syndrome in adults clinic

      ea0019p206
    • Post-natal stress in birds: a novel experimental model to understand glucocorticoid programming of the HPA axis

      ea0019p207
    • Antisense oligonucleotides to correct the aberrant growth hormone receptor mRNA splicing caused by the pseudoexon 6[Psi] defect

      ea0019p208
    • The effect of age on insulin-like growth factor-I and pro-collagen type III N-terminal peptide in elite adolescent athletes and its influence on the detection of growth hormone abuse

      ea0019p209
  • Neuroendocrinology and behaviour
  • • EGFR antagonists promote disinhibited retinal ganglion cell axon regeneration by a glial-dependent mechanism

      ea0019p210
    • Characterisation of neurokinin B family members including the identification of novel splice variants and processed peptides in neuroendocrine tissues

      ea0019p211
    • Stimulation of PKC[beta]II -dependent ERK1/2 signalling by endokinin B and substance P may cause gene transcription via the tachykinin NK1 receptor in astrocytoma cells

      ea0019p212
    • Involvement of excitatory amino acid neurotransmitters pathway in the regulation of basal/stimulated GH secretion in primates

      ea0019p213
    • Distribution of somatostatin receptors in the hypothalamus of control and prenatally androgenised ewes

      ea0019p214
    • Rising endogenous sex steroids adversely affect performance of certain cognitive tasks across pregnancy

      ea0019p215
    • Attribution matters: the impact of Klinefelter's syndrome on psycho-social functioning

      ea0019p216
    • 'It's your hormones': a qualitative exploration of men's experiences of Klinefelter's syndrome

      ea0019p217
    • Novel hypothalamic regulation by the vitamin A signalling pathway

      ea0019p218
    • Endogenous excitatory amino acid neurotransmitters are involved in prolactin release in response to insulin-induced hypoglycemia

      ea0019p219
    • Endogenous EAA regulate PRL secretion through opioidergic pathway in primates

      ea0019p220
    • Hypomania in a patient receiving testosterone replacement

      ea0019p221
    • Expression of exon 3 of the growth hormone receptor gene in adults with growth hormone deficiency on growth hormone replacement therapy

      ea0019p222
    • Immediate memory deficits in patients with non-functioning adenoma: an fMRI pilot investigation

      ea0019p223
  • Pituitary
  • • Cloning and expression of calcium/calmodulin-dependent protein kinase ii isoforms in the developing zebrafish (Danio rerio)

      ea0019p224
    • Transient hypopituitarism following a viral illness

      ea0019p225
    • Metastatic renal cell carcinoma masquerading as a vascular pituitary tumour

      ea0019p226
    • Effect of the d3 growth hormone receptor genotype on GH responsiveness in adult hypopituitary patients

      ea0019p227
    • Severe acute psychosis precipitated by replacement dose hydrocortisone in newly diagnosed panhypopituitarism

      ea0019p228
    • Outcome following transsphenoidal adenectomy as treatment for non-responsive prolactinomas

      ea0019p229
    • Echocardiographic findings in patients on long-term dopamine agonist therapy

      ea0019p230
    • Acromegaly: the contribution of prolactin in the management

      ea0019p231
    • An unusual case of a disappearing TSHoma

      ea0019p232
    • An unusual case of pituitary disease

      ea0019p233
    • 'Reasonably good' - results of a survey on pituitary patients' satisfaction with information and support from healthcare professionals

      ea0019p234
    • Dealing with infertility as a consequence of a pituitary condition

      ea0019p235
    • Dual pathology for headache masquerading as dopamine agonist intolerance

      ea0019p236
    • Assessment of in vivo proliferation rates in pituitary tumours of multiple endocrine neoplasia type 1 knockout mice: implications for evaluating treatment

      ea0019p237
    • CSF rhinorrhoea - a rare complication of medical management of giant prolactinomas

      ea0019p238
    • Familial prolactinoma occuring in association with SDHB mutation positive paraganglioma

      ea0019p239
    • Endocrine consequences of childhood traumatic brain injury

      ea0019p240
    • The acromegalic cardiovascular and respiratory outcomes with primary analogue therapy (A.C.R.O.P.A.T.) trial

      ea0019p241
    • An analysis of the dose of levothyroxine in patients with central hypothyroidism

      ea0019p242
    • Growth hormone deficiency in adults: the NICE criteria do not discriminate an adverse cardiovascular phenotype

      ea0019p243
    • Abnormal cortisol metabolism in growth hormone deficient adults; the role of hydrocortisone replacement therapy and effect on body composition

      ea0019p244
    • Effect of ACTH deficiency and hydrocortisone replacement dose on mortality in patients with acromegaly

      ea0019p245
    • The high dose dexamethasone suppression test is dead

      ea0019p246
    • The specificity of ACTH recognition by the MC2R

      ea0019p247
    • Anaemia leading to diagnosis of pan-hypopituitarism in an elderly gentleman

      ea0019p248
    • Exposure to a cocktail of environmental chemicals in sewage sludge: effects on foetal and post pubertal pituitary gonadotrophs in sheep

      ea0019p249
    • Wnt signalling in oestrogen-induced lactotroph proliferation

      ea0019p250
    • Differential effects of dopamine agonists at D2S and 5HT2B receptors

      ea0019p251
    • A retrospective analysis of management and follow up of patients with macroprolactinoma-12 year incident data from the South Tees endocrine register

      ea0019p252
    • A case of headache and severe hyponatraemia - SIADH or pituitary apoplexy?

      ea0019p253
    • Acromegaly: an audit of treatment outcomes

      ea0019p254
    • Successful treatment of a combined GH/TSHoma using SOM230

      ea0019p255
    • A case of FSH secreting pituitary adenoma

      ea0019p256
    • Secondary thyrotoxicosis in a patient with acromegaly presenting with recurrent atrial fibrillation following transphenoidal surgery

      ea0019p257
    • Growth hormone replacement and its effect on muscle strength in GH-deficient adults: a meta-analysis

      ea0019p258
    • Pituitary diseases and arachnoid cysts: more than a coincidence?

      ea0019p259
    • Hypoglycaemia during the insulin stress test - how low do we go?

      ea0019p260
    • A case of pituitary stalk tumour posing management challenge

      ea0019p261
    • Improvements in insulin sensitivity outweigh a decline in pancreatic beta-cell function in newly diagnosed acromegalic subjects treated with primary medical (Somatuline Autogel[reg]) therapy

      ea0019p262
    • Plasmacytoma: an unusual cause of a pituitary mass lesion

      ea0019p263
    • Hypogonadism secondary to hyperprolactinaemia: successful treatment and its adverse consequences....

      ea0019p264
    • Multiple neoplasms in acromegaly

      ea0019p265
    • Fifteen years experience of repeated colonoscopic screening of patients with acromegaly shows a high incidence of new colonic neoplasia and allows for effective screening guidelines

      ea0019p266
    • Predicting surgical cure rate of acromegaly based on degree of lateral tumour extension on MRI - a retrospective blinded study

      ea0019p267
    • Two successful pregnancies in partially treated acromegaly followed by spontaneous improvement of GH axis postpartum

      ea0019p268
    • The management of microprolactinoma: are we following the guidelines for dopamine agonist withdrawal?

      ea0019p269
    • Factors determining the remission of microprolactinomas after dopamine agonist withdrawal

      ea0019p270
    • The challenges in managing prolactinomas in patients with psychiatric illness treated with antipsychotic medication

      ea0019p271
    • A single early morning serum cortisol in the early post operative period following transphenoidal surgery for pituitary tumours accurately predicts hypothalamo-pituitary-adrenal function

      ea0019p272
    • Pituitary natriuretic peptide signalling via guanylyl cyclase-B (GC-B) receptors in GH3 somatolactotrophs is regulated by protein phosphatase activity but not receptor internalisation

      ea0019p273
    • Body composition response following long-term GH replacement in adults with craniopharyngioma associated hypopituitarism

      ea0019p274
    • Surgical outcome of acromegaly: significance of pre-operative prolactin and GH levels on likelihood of surgical cure

      ea0019p275
    • Hyperthyroxinaemia with non-suppressed TSH in a clinically euthyroid woman with an unusual sella mass

      ea0019p276
    • Serial imaging in macroprolactinomas: for how long?

      ea0019p277
    • Iron deficiency anaemia due to hypopituitarism

      ea0019p278
    • Macroprolactinaemia: what is the long-term prognosis? Results from an original series of 55 patients after 10 years clinical follow-up

      ea0019p279
  • Reproduction
  • • Effect of orexin infusion into third ventricle on the GnRH and LH secretions in the prepubertal rat fed restricted diet

      ea0019p280
    • Effect of rimonabant and metformin on GIP and GLP-1 in obese women with polycystic ovary syndrome

      ea0019p281
    • Clot structure and fibrinolysis in individuals with polycystic ovary syndrome: the effects of metformin, orlistat and pioglitazone treatment

      ea0019p282
    • Metabolic effects of insulin and modification by androgen in immortalised mouse granulosa cells

      ea0019p283
    • Prenatal testosterone exposure causes altered large antral follicle differentiation in sheep

      ea0019p284
    • Evidence for discordant granulosa cell proliferation in ovaries of prenatally androgenised sheep: a model for polycystic ovary syndrome

      ea0019p285
    • Inhibin B and AMH are NOT predictors of serum testosterone in young men after cancer

      ea0019p286
    • Dihydrotestosterone increases KiSS1 expression in adipose and pituitary tissue, but not in hypothalamus, in a rat model of polycystic ovary syndrome (PCOS)

      ea0019p287
    • IGF-2 receptor signalling and trophoblast cell turnover

      ea0019p288
    • The importance of a specialized adult Turner Syndrome clinic

      ea0019p289
    • Serum anti-Mullerian hormone and The HCG stimulation test for investigating boys with disorders of sex development

      ea0019p290
    • The effect of cafeteria diet feeding on maternal adaptation to pregnancy during pre, early and late gestation

      ea0019p291
    • The influence of changes in macronutrient intake during gestation on gene expression of on glucocorticoid receptor (GR) and 11-beta-hydroxysteroid dehydrogenase 1 and 2 (11[beta]hsd1 and 2) in the livers of neonatal pigs; effect of size at birth

      ea0019p292
    • Does skin thickness affect the absorption of Testogel?

      ea0019p293
    • The effect of a low protein diet on renal fluid homeostasis and plasma volume during pregnancy in the rat

      ea0019p294
    • Assessment of endothelial function in pregnancy

      ea0019p295
    • Patient reported outcomes for the use of metformin in polycystic ovarian syndrome (PCOS)

      ea0019p296
    • Total testosterone correlates better than free testosterone with metabolic disturbance in diabetes

      ea0019p297
    • Successful pregnancy and delivery of triplets in patient with BMI of 80

      ea0019p298
    • Fertility in adults with congenital adrenal hyperplasia: congenital adrenal hyperplasia adult study executive (CaHASE)

      ea0019p299
    • Plasma kisspeptin levels in hypertensive diseases of pregnancy and the identification of kisspeptin in amniotic fluid

      ea0019p300
    • Functional pharmacology of prostaglandin E receptors in isolated human myometrium before and after labour-onset

      ea0019p301
  • Steroids
  • • Differential transcription of 11[beta]-hydroxylase and aldosterone synthase alleles in human adrenocortical tissue

      ea0019p302
    • Report of the first missense mutation of MRAP within the MC2R interaction domain in a family causing FGD

      ea0019p303
    • Modified-release hydrocortisone to provide circadian cortisol profiles

      ea0019p304
    • Differences in aldosterone synthase and 11[beta]-hydroxylase genes between Caucasian and Afro-Caribbean hypertensive families

      ea0019p305
    • Prenatal dexamethasone programmes renal 11[beta]-hydroxysteroid dehydrogenase type 2 expression

      ea0019p306
    • Hyperglycaemia presenting as adrenal insufficiency in type 1 diabetes

      ea0019p307
    • Cushing's syndrome presenting as weight loss

      ea0019p308
    • Corticosteroid-binding globulin (CBG) deficiency caused by a novel mutation in exon 3

      ea0019p309
    • Simultaneous measurement of cortisol and cortisone in saliva by LC-MS/MS: application in basal and stimulated conditions

      ea0019p310
    • Effects of endogenous and exogenous hypercortisolemia on low-dose ACTH outcome in humans

      ea0019p311
    • A biphasic rhythm of testosterone secretion: evidence for regulation by glucocorticoids

      ea0019p312
    • Dehydroepiandrosterone steroids are regulators of immune function via leukocyte annexin 1

      ea0019p313
    • The adipokine, Pre-B cell colony enhancing factor (PBEF)/visfatin, activates steroidogenic acute regulatory protein (StAR) protein expression and steroid production in human adrenocortical-H295R-cells via MAPK and PI3/AkT signalling pathways

      ea0019p314
    • Orexin-stimulated MAP Kinase cascades are activated through multiple G-protein signalling pathways in human H295R adrenocortical cells: differential regulation by orexin A and orexin B

      ea0019p315
    • Regulation of 11[beta]-hydroxysteroid dehydrogenase type 1 activity in myocytes by differentiation stage, GH/IGF1 and glucocorticoids

      ea0019p316
    • Cofactors and modify Cofactors and modifications of the glucocorticoid receptor

      ea0019p317
    • Associated health conditions and occupational status are risk factors for adrenal crisis in treated Addison's disease

      ea0019p318
    • Testosterone increases 11[beta]-hydroxysteroid dehydrogenase type 1 (11[beta]-HSD1) expression in the rat heart

      ea0019p319
    • Sexual dichotomy in long term growth trajectories of children with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH)

      ea0019p320
    • MicroRNA: a novel post transcriptional regulator of 11[beta]-hydroxlase (CYP11B1) and aldosterone synthase (CYP11B2)

      ea0019p321
    • Group education for emergency hydrocortisone injection

      ea0019p322
    • Long-term consequences of auto-immune primary adrenal failure

      ea0019p323
    • Expression of 11[beta]-hydroxysteroid dehydrogenase (11[beta]-HSD) enzymes in mouse oocytes

      ea0019p324
    • The effects of glucocorticoids on first trimester trophoblast

      ea0019p325
    • Adrenal insufficiency due to heparine induced thrombocytopenia

      ea0019p326
    • Measuring cortisone production in man using a new stable isotope tracer

      ea0019p327
    • Homeopathic medication and hyperthalamic-pituitary-adrenal (HPA) axis

      ea0019p328
    • Testosterone deficiency in the testicular feminised mouse model is significantly associated with the development of liver steatosis: a mechanism that is independent of the androgen receptor

      ea0019p329
    • Glucocorticoid regulation of 11[beta]-hydroxysteroid dehydrogenase type 1 in dermal fibroblasts

      ea0019p330
    • A case of triple A syndrome: more than just glucocorticoid deficiency

      ea0019p331
    • Mitosis regulates GR trafficking and impacts GR function

      ea0019p332
    • Altered subcellular trafficking and gene regulation suggest a distinct role for GR gamma

      ea0019p333
    • GR is hyperphosphorylated during mitosis and associates with the mitotic spindle

      ea0019p334
    • Epigenetic silencing of the GR and defining the pro-apoptotic actions of GR expression in human cancer cell lines

      ea0019p335
    • 1,25-dihydroxyvitamin D3 increases the expression of intercellular adhesion molecule-1 (ICAM-1) and interleukin 8 (IL-8) in a human proximal tubule cell line

      ea0019p336
    • The role of serum and urinary steroids in the monitoring of adults with congenital adrenal hyperplasia

      ea0019p337
  • Thyroid
  • • Value of patient body weight for thyroxin replacement therapy after total thyroidectomy for bengin thyroid disorders

      ea0019p338
    • Association between thyroid hormones, insulin resistance and metabolic syndrome

      ea0019p339
    • Relation between thyrotropinemia and severity of obesity in children

      ea0019p340
    • Efficacy of radioiodine therapy in the treatment of elevated serum thyroglobulin in patients with differentiated thyroid carcinoma and negative whole-body iodine scan

      ea0019p341
    • 'Help! I Can't Walk': a case of thyrotoxic hypokalaemic periodic paralysis

      ea0019p342
    • Post radioiodine monitoring: do patients feel telephone consultations are an acceptable part of a nurse-led clinic?

      ea0019p343
    • Carbimazole induced hearing loss

      ea0019p344
    • UK trends in prescribing thyroid hormone and patient satisfaction survey

      ea0019p345
    • Graves' thyrotoxicosis in a patient with previous thyroid lymphoma and thyroid adenoma

      ea0019p346
    • Misdiagnosed thyrotoxicosis

      ea0019p347
    • Carbimazole-induced acute cholestatic hepatitis in patient with Graves' disease

      ea0019p348
    • The outcome of treatment of relapsed hyperthyroidism with a fixed dose of 550 MBq radioiodine

      ea0019p349
    • An audit on assessment of effectiveness of a database follow-up system in pregnant women with hypothyroidism

      ea0019p350
    • Generalised resistance to thyroid hormone secondary to a novel heterozygous missense mutation with coincidental toxic nodular goitre

      ea0019p351
    • A retrospective study of radio-iodine treatment outcomes in thyrotoxicosis

      ea0019p352
    • Thyroid dysfunction in a Hepatitis C population treated with interferon therapy

      ea0019p353
    • Thyroxine induced cardiac failure in a young hypothyroid

      ea0019p354
    • Variable dosage radio-iodine regimes for the treatment of hyperthyroidism: analysis of outcome and its implications in treatment planning

      ea0019p355
    • Levothyroxine and iron in pregnancy: right dose, wrong time?

      ea0019p356
    • Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination T4/T3 therapy in patients on thyroid hormone replacement

      ea0019p357
    • Thyroxine dose adjustment during pregnancy

      ea0019p358
    • Audit of the treatment of primary hypothyroidism in a general practice population

      ea0019p359
    • The management of massive goitre in a DGH

      ea0019p360
    • Establishing the appropriate population specific reference range for fetal thyroid measurements

      ea0019p361
    • A case of papillary carcinoma associated with Cowdens syndrome

      ea0019p362
    • Thyroid function in a cohort of eighty five year olds: the Newcastle 85+ study

      ea0019p363
    • The patient experience of services for thyroid eye disease in the United Kingdom: a questionnaire survey

      ea0019p364
    • Reversible apparent pulmonary fibrosis in severe hypothyroidism

      ea0019p365
    • Anticonvulsant induced central hypothyroidism

      ea0019p366
    • A case of nongoitrous Hashimoto's thyroiditis presenting as severe thyrotoxicosis accompanied by Pancytopaenia and later developing hypothyroidism

      ea0019p367
    • Efficacy and complications of radioiodine therapy in benign thyroid disease

      ea0019p368
    • Epitopes for calcium-sensing receptor antibodies in patients with autoimmune polyendocrine syndrome type 1 are located in the N-terminal of the extracellular domain

      ea0019p369
    • The effects of the thyroid hormone transporter MCT8 on human placental development

      ea0019p370
    • Enlargement of the thyroid gland in a heterozygous PBF knock-in transgenic mouse model

      ea0019p371
    • Confirmation of the chromosome 2q37 region as a susceptibility locus for Graves' disease

      ea0019p372
    • Further evidence for a key role of FcGR2a in autoimmunity

      ea0019p373
    • Clonal relationships between TSH receptor stimulating antibodies illustrate the effect of hypermutation on antibody function

      ea0019p374
    • Association of another member of the FCRL family with Graves' disease: further evidence for disrupted B cell signalling in disease pathogenesis

      ea0019p375
    • Unusual case of absolute thyroxin intolerance

      ea0019p376
    • Management of maternal hypothyroidism in the joint antenatal endocrine clinic

      ea0019p377
    • Severe dilated cardiomyopathy and hyperthyroidism

      ea0019p378
    • Evaluation of thyroid ultrasound requests and fine needle aspiration in Northwest London Trust Hospital

      ea0019p379
    • Hypothyroidism in adult survivors of childhood malignancy

      ea0019p380
    • Multinodular goitre and sleep apnoea

      ea0019p381
    • Thyroidectomies in children

      ea0019p382
    • A lethal combination of thyroid lymphoma and congenital tracheal stenosis

      ea0019p383
    • Thyroid abnormalities in pegylated interferon treated hepatitis C patients

      ea0019p384
    • Audit on the management of thyrotoxicosis in the clinic at a District General Hospital

      ea0019p385
    • Spurious TFT results in clinically euthyroid patients: a lesson in interference

      ea0019p386
    • PTPN22 genotype is a determinant of age of onset of Graves' disease

      ea0019p387
    • HIF-1[alpha] and [beta]-catenin functionally interact in the regulation of carbonic anhydrase-IX (CA-IX), an important marker of tumour hypoxia

      ea0019p388
    • High levothyroxine requirement: more than just compliance!

      ea0019p389
    • The management of thyroid fine needle aspiration (FNA) cytology samples reported as benign (Thy2): an audit of practice at a teaching hospital

      ea0019p390
    • Thyroid nurse-led clinic service: a positive healthcare initiative

      ea0019p391
    • A thyroid nurse-led service: patients' perspective: an audit

      ea0019p392
    • Acute changes in thyroid function during treatment with sorafenib, a tyrosine kinase inhibitor

      ea0019p393
    • Is long-term follow-up after radio-iodine therapy safe in the current UK health-care climate?

      ea0019p394
    • Access to thyroid ultrasound: audit of clinical efficiency & governance of the rapid access one-stop thyroid ultrasound FNA clinic

      ea0019p395
    • Hyperthyroidism: retrospective audit on patients' follow-up post radioiodine therapy

      ea0019p396