ea0012s38 | Endocrinology of ageing | SFE2006
Bouloux P
, Solomons A
, Carr H
, Brothwood T
There are a number of endocrine changes which occur during the aging process, including changes in the growth hormone IGF1 axis, a fall in DHEAS levels, changes in the renin-angiotensin system, and alterations in the hypothalamo-pituitary gonadal axis. Testosterone levels decline with age, with an average decrease in testosterone levels of approximately 1.5% per year. The prevalence of subphysiological testosterone levels is approximately 20% by the age of 50 and 50% by...