Endocrine Abstracts

Thyroid hormone is essential for the metabolic function of all tissues throughout life and for the development of different organs, notably the brain. Although the thyroid gland mainly secretes T4, most actions of thyroid hormone are initiated by binding of T3 to its nuclear receptor. The biological activity of thyroid hormone in target cells is determined by the intracellular T3 concentration which depends on the circulating levels of T3 and its precursor T4, the activity of ...

Kenneth S Korach, National Institute of Environmental Health Sciences, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA AbstractKenneth S Korach is the Program Director of the Environmental Disease and Medicine Program, Chief of the Laboratory of Reproductive and Developmental Toxicology at the National Institute of Environmental Health...