Endocrine Abstracts

Transthyretin (TTR) is a plasma and cerebrospinal fluid (CSF)-circulating protein. Besides the primordially attributed systemic role as transporter molecule of thyroxine (T4) and retinol (through the binding to retinol-binding protein (RBP)), TTR has been recognised as a protein with important functions in several aspects of the nervous system physiology. TTR has been shown to play an important role in behaviour, cognition, amidated neuropeptide processing, and nerv...

Maria João Mascarenhas Saraiva received a BSc in Biology from the University of Porto, Portugal, in 1976, and an MSc in Biochemistry from the University of London, in 1978. Between 1980 and 1984, she did a PhD in biochemistry at the University of Porto, and qualified as Professor of Biochemistry in the University of Porto in 1991. She worked for different periods as a Visiting Scientist at the ...