ea0035pl2 | Advances in molecular pathogenesis of thyroid cancer therapeutic implications | ECE2014
Santisteban Pilar
, Sastre-Perona Ana
, Wert-Lamas Leon
, Riesco-Eizaguirre Garcilaso
Thyroid cancer is one of the endocrine pathologies whose incidence is increasing, although in general terms it has a good outcome. However, some patients develop aggressive forms that are untreatable and the molecular basis is poorly understood. These aggressive forms are basically well-differentiated thyroid carcinomas that undergo dedifferentiation and poorly differentiated and anaplastic carcinomas. All of them have lost Na/I Symporter (NIS) function leading to radioiodine-...