ea0029s22.1 | Pituitary tumorigenesis | ICEECE2012
Melmed S.
Pituiatry tumors account for about 15% of all intracranial neoplasms. They arise from pituitary cell types due to both cell cycle trophic dysruptions leading to adenomatous growth, as well as a coupling of specific hormone gene over-expression. Thus, both tumor growth characteristics, as well as hormonal excess are the hallmarks of these invariably benign tumors. They may lead to both central compressive features due to mass expansion or invasion, as well as to specific clinic...