ea0019s4 | Society for Endocrinology European Medal Lecture | SFEBES2009
Wiersinga Wilmar
Early stages of thyroid autoimmunity can be identified by thyroid hypoechogenecity and/or thyroid antibodies in serum. To get better insight in these early stages, we assembled a large group of women at risk for AITD (all had one or more 1st or 2nd degree relatives with AITD), who were in self-proclaimed good health and followed for 5 yr (the Amsterdam AITD cohort).At study entrance, euthyroid women had reduced CD25 expression on CD4+T-cells and lower se...