ea0016s19.3 | Hormone receptors and adipose tissue | ECE2008
Wells Timothy
Binding of the gastric hormone ghrelin to its cognate receptor, GHS-R1a, is dependent upon the acylation of its third (serine) residue. Although acute exposure to ghrelin stimulates the secretion of growth hormone (a potent lipolytic signal), chronic exposure to ghrelin promotes fat deposition1.We have shown that in intra-abdominal depots, ghrelin-induced fat accumulation is depot-specific, time-dependent, due to lipid accumulation ...