ea0016gh1 | The Geoffrey Harris Prize Lecture | ECE2008
Chrousos George P
The existence of the principle of hypothalamic hypophysiotropic factors, predicted so prophetically by G W Harris in the 1940s, has been confirmed by irrefutable evidence. This principle is central to the survival of complex organisms as both individuals and species. Life exists through maintenance of a complex dynamic equilibrium, or homeostasis, that is constantly challenged by intrinsic or extrinsic adverse forces, or stressors. Thus, stress is defined as a state of t...