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10th European Congress of Endocrinology

Plenary Lectures

Graves’ ophthalmopathy – problems solved and new questions to be answered

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ea0016pl6 | Graves’ ophthalmopathy – problems solved and new questions to be answered | ECE2008

Graves’ ophthalmopathy: problems solved and new questions to be answered

Wiersinga Wilmar M

Graves’ ophthalmopathy (GO) remains the most enigmatic presentation of thyroid autoimmunity. Although many issues regarding its pathogenesis and management have been solved, they are still outnumbered by unresolved open questions.Pathogenesis: Orbital fibroblasts (OF) have been recognized as the primary target cells of the autoimmune attack. Cytokine-induced excessive secretion of glycosaminoglycans and differentiation of a subset of OF into adipocy...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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