Endocrine Abstracts

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The hypothalamus plays a central role in the neuroendocrine regulation of energy homeostasis and appetite. Congenital or acquired disruption of hypothalamic nuclei disrupts the balance between energy intake and expenditure is leading to rapid and excessive weight gain. Hypothalamic obesity (HO) is further complicated by disturbances in the hypothalamic-pituitary axis, sleep disruption, visual impairment, and neurological and vascular sequelae. Among suprasellar tumours, cranio...