Endocrine Abstracts

Thyroid cancer is the most common endocrine malignancy and over the past 40 years there has been a dramatic rise in incidence globally, largely due to the detection of small low-risk papillary cancers as a consequence of increased use of thyroid ultrasonography. The vast majority of these differentiated thyroid cancers are small, often incidental, slow growing and carry an excellent prognosis. The management of these tumours has undergone a dramatic change in the last 5-10 yea...

Management of thyroid disease in pregnancy can be challenging. My talk will focus on the appropriate interpretation of thyroid function tests during pregnancy, the avoidance of over treatment of marginal TSH/FT4 values, appropriate and prompt management of hypothyroidism and management of thyrotoxicosis due to various aetiologies. I will also touch on fetal surveillance and neonatal TFT testing. ...

Resistance to Thyroid Hormone-β (RTHβ) is a rare disorder characterised by hormone resistance in the pituitary-thyroid axis which results in elevated, circulating thyroid hormones. Although some patients display features of hyperthyroidism, the natural history of RTHβ with respect to cardiovascular disease or death is unknown. In this presentation, I will review our recent data which used a linked health record approach in Wales to demonstrate reduced survival a...