SFEIES24 Poster Presentations Diabetes & Metabolism (68 abstracts)
Characteristics of hypoglycaemia and its outcomes in people with continuous glucose monitoring (CGM) devices: pilot data from the DEKODE hypoglycaemia study
Amanda Ling Jie Yee 1 , Aditya Bal 1 , Charles Page 1 , Kalyaani Persad 1 , Mariam Idrissi 1 , Pratik Choudhary 2 , Pranav Viswanath Iyer 1 , Punith Kempegowda 3,4 , Sam Sherratt-Mayhew 1 & DEKODE Hypoglycaemia Working Group 3
1University of Birmingham, Birmingham, United Kingdom; 2Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom; 3Institute of Applied Health Research, Birmingham, United Kingdom; 4Queen Elizabeth Hospital, Birmingham, United Kingdom
Background: Continuous Glucose Monitoring (CGM) devices are increasingly used to track blood glucose levels in individuals with diabetes. Despite widespread agreement on their benefits, limited information exists regarding the characteristics and clinical outcomes when these individuals experience hypoglycemia.
Objective: To investigate the characteristics of hypoglycaemia and its outcomes in people using CGM devices.
Methods: This retrospective study was conducted across five hospitals in the UK between October 2023 and January 2024. Participants included those using CGM devices who experienced hypoglycemia during the study period and were treated for it in the five hospitals. Data collected encompassed sociodemographic information, precipitating factors, management strategies, outcomes, and the total duration of hypoglycaemia. Data analysis was performed using SPSS 29.0.
Results: A total of 104 hypoglycaemic episodes (96 with type 1 diabetes, 8 with type 2 diabetes) were identified, with 69 occurring in an inpatient setting. Among the participants, 50% were male. The median age was 35.5 years (interquartile range [IQR] 34.0-50.0 years), and the median Charlson comorbidity index was 5 (IQR 4-6). The median HbA1C level before admission was 75 mmol/mol (IQR 60-98 mmol/mol). Hypoglycaemia episodes were classified as follows: 61.5% at level 1, 31.7% at level 2, and 6.7% at level 3. The median duration of hypoglycaemia was 69 minutes (IQR 22-110 minutes). The primary precipitating factor was missed meals (42.3%), and the others included incorrect insulin dosage (1.9%), intercurrent illness (3.8%), multiple factors (30.8%), and other unclear reasons (21.2%). During these episodes, 7.2% patients received glucagon, but only 1.9% were prescribed glucagon upon discharge.
Conclusion: Missed meals were the most common precipitating factor for hypoglycaemia. Notably, only a small percentage of patients were prescribed with glucagon upon discharge. These findings emphasise the need for improved education for healthcare professionals on preventative strategies of hypoglycaemia in patients using CGM devices.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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