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Endocrine Abstracts (2024) 104 P72 | DOI: 10.1530/endoabs.104.P72

SFEIES24 Poster Presentations Diabetes & Metabolism (68 abstracts)

Impact of new start hybrid closed loop (HCL) insulin pump therapy on glycaemic control, diabetes distress and hypoglycaemia awareness in tallaght university hospital (TUH)

Mary Horan , Caitlin Thomas , Mary Finn , Rexy George , Celine Kenna , Breda Morris , Ciara O’Brien , Kevin Moore & Ferrah Shaamile


Tallaght University Hospital, Dublin, Ireland


Background: Diabetes nurses and dietitians, with support from the endocrinology team, led a restart of the insulin pump service for pump-naïve patients in TUH in May 2023.

Aim: To compare glycaemic control, diabetes distress and hypoglycaemia awareness pre and post HCL system use in the first 6 months.

Research Design: Patients who had completed BERGER carbohydrate counting course, attended a carbohydrate counting refresher. Food and insulin diaries, HbA1c and retinal screening results were reviewed to ensure safe and accurate HCL system settings. Patients who started HCL therapy (Medtronic 780G pump with Guardian 4 CGM) from May to October 2023 were evaluated using GOLD hypoglycaemia awareness screening tool and Diabetes Distress Scale (DDS-17) or PAID. HbA1c and CGM data were compared.

Results

Table 1. Comparison of glycaemic control in patients with data both pre and post HCL therapy
PrePost
nMeanSDnMeanSD
HbA1c mmol/mol (%)1664.7 (8.1%)10.31656.1 (7.3%)6.9
Percentage Time in Range1841.718.11872.69.8
Table 2. Proportion of patients meeting time in range targets and Diabetes Distress and Hypoglycaemia Awareness pre and post HCL Therapy. *Meeting all CGM Targets: Time in range>70%, Low<4%, very low<1%, very high<5%
PrePost
No.%No. %
Time in Range >70%211.111266.67
Meeting All CGM Targets*1 5.56738.89
Severe Diabetes Distress531.25425.00
Moderate Diabetes Distress850.00531.25
No Diabetes Distress318.75743.75
Impaired Hypoglycaemia Awareness637.50531.25
Normal Hypoglycaemia Awareness956.251062.50
Undetermined Hypoglycaemia Awareness1 6.2516.25

Table 1. Comparison of glycaemic control in patients with data both pre and post HCL therapy
PrePost
nMeanSDnMeanSD
HbA1c mmol/mol (%)1664.7 (8.1%)10.31656.1 (7.3%)6.9
Percentage Time in Range1841.718.11872.69.8
Table 2. Proportion of patients meeting time in range targets and Diabetes Distress and Hypoglycaemia Awareness pre and post HCL Therapy. *Meeting all CGM Targets: Time in range>70%, Low<4%, very low<1%, very high<5%
PrePost
No.%No. %
Time in Range >70%211.111266.67
Meeting All CGM Targets*1 5.56738.89
Severe Diabetes Distress531.25425.00
Moderate Diabetes Distress850.00531.25
No Diabetes Distress318.75743.75
Impaired Hypoglycaemia Awareness637.50531.25
Normal Hypoglycaemia Awareness956.251062.50
Undetermined Hypoglycaemia Awareness1 6.2516.25

Conclusion: Restart of the TUH insulin pump service for pump naïve patients enabled 24 patients to successfully start HCL therapy in this 6 month period. Glycaemic control (HbA1c and time in range), diabetes distress and hypoglycaemia awareness improved.

Volume 104

Joint Irish-UK Endocrine Meeting 2024

Belfast, Northern Ireland
14 Oct 2024 - 15 Oct 2024

Society for Endocrinology 

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