Endocrine Abstracts

For over 30 years my laboratory has studied how hormones regulate metabolism and how this regulation is disrupted in metabolic disease. Some of these actions are mediated by the central nervous system and affect appetite, food intake and other behaviours. In this talk I will present data on three hormones: insulin, leptin and GDF15. I will briefly discuss recent advances in the understanding of human insulin resistance, the role of leptin melanocortin signalling in obesity and...