BSPED2024 Poster Presentations Diabetes 1 (8 abstracts)
Diabetic retinopathy screening in laotian children with diabetes: a collaboration between singapore national eye centre and action4diabetes
Sze Ng 1,2,3 , Amphayvanh Manivong 4 , Daoheuang Phommachack 4 , Khamtavanh Khambuapha 5 , Fiona Ooi 6 , Reuben Foo 7 , Anna Tan 7 & Ngee Lek 8
1Edge Hill University, Ormskirk, United Kingdom; 2University of Liverpool, Liverpool, United Kingdom; 3Mersey and West Lancashire Teaching Hospitals NHS Trust, Southport, United Kingdom; 4Mahosot Hospital, Vientiane, Lao, People’s Democratic Republic; 5University of Health Sciences, Vientiane, Lao, People’s Democratic Republic; 6Action4Diabetes, Surrey, United Kingdom; 7Global Ophthalmology Office, Singapore National Eye Centre, Singapore, Singapore; 8Department of Paediatrics, KK Women’s and Children’s Hospital, Singapore, Singapore
Background: Laos is a LMIC in South-east Asia (SEA) where health coverage does not provide for insulin and blood glucose testing. Before 2016, no person was known to have survived type 1 diabetes (T1D). Action4Diabetes (A4D) has since been providing insulin and blood glucose testing kits for Laotian patients with T1D. As the patients are now surviving and living with T1D, early detection of diabetes-related complications becomes imperative. In March 2024, a diabetic retinopathy (DR) screening session took place for the first time at the National Centre of Ophthalmology in Laos.
Aim: To report the patient demographics and eye screening outcomes in Laos.
Methods: Patients attending Mahosot Hospital, Vientiane, Laos, were identified to undertake DR screening conducted by SNEC ophthalmologists and healthcare professionals from its Global Ophthalmology Office who were on a volunteering mission trip in Laos. Patient demographics, insulin treatment regimen, and HbA1c were collated together with DR screening and other eye-check outcomes.
Results: 19 patients (10 male; 53%) diagnosed with T1D between March 2016 and September 2023 at median 11.4 years (range 1−18 years) were DR-screened at median 16.0 years (8.2−21.9 years). At diagnosis, 12 patients (63%) were in diabetic ketoacidosis. From diagnosis, all patients received twice-daily pre-mixed 30/70 insulin. Since September 2023, 10 of the patients (53%) switched to basal-bolus insulin regimen. Most recent median HbA1c was 7.7% or 59 mmol/mol (5.0−14.0%, or 30−128 mmol/l). As at the time of DR screening, median duration of diabetes was 4.0 years (0.5−8.0 years). Using ophthalmic examination, none of the 19 patients was found to have DR. One patient had newly diagnosed refractive deficit and was issued prescription for glasses.
Conclusions: Through mutual aid and collaborations, we plan to conduct subsequent, regular sessions to screen for diabetes-related complications in more patients in Laos and other LMICs in SEA.
Volume 103
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Endocrine Abstracts
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