BSPED2024 Poster Presentations Diabetes 6 (8 abstracts)
An analysis of the presence of vascular complications from type 1 diabetes mellitus based on ethnicity and deprivation quintile in a single centre
Afiya Andrews 1 , Chamila Balagamage 1 , Melanie Kershaw 1 , Zainab Mohammed 1 , Jan Idkowiak 1,2 , Suma Uday 1,2 , Vrinda Saraff 1 , Lesley Drummond 1 , Ruth Krone 1 & Renuka. P. Dias 1,3
1Department of Diabetes and Endocrinology, Birmingham Children’s Hospital, Birmingham, United Kingdom; 2Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom; 3Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom
Introduction: The National Paediatric Diabetes Audit (NPDA) Report for 2022 to 2023 recommended that all children and young people should have equitable access to diabetes care, regardless of social deprivation, ethnicity, or geography.
Aim: To investigate if ethnicity or socio-economic status impacted the development of vascular complications in patients with type 1 diabetes mellitus (T1DM) undergoing annual diabetes screening.
Methods: Retrospective case notes review (2021-2024) was undertaken for patients cared for at Birmingham Children’s Hospital (BCH) aged over 12 years with a diagnosis of T1DM for at least 3 years. Data collected included demographics, Index of Multiple Deprivation (IMD) quintiles and the presence of vascular complications including microalbuminuria, diabetic retinopathy, blood pressure and hypercholesterolaemia. Statistical analyses were performed using Fisher’s exact t-test and Spearman correlation.
Results: 160 patients met the eligibility criteria (49% male and 51% female). The median age at diagnosis was 8 (0.9-16) years and the median HbA1c was 61 (37- 143) mmol/mol. The majority, 56% were from IMD quintile 1, 19% from quintile 2, 16% from quintile 3, 4% and 5% from quintiles 4 and 5 respectively. 41% were of White ethnicity followed by Asian ethnicity at 35%, Black at 11%, Mixed/Multi-ethnic at 6% and 7% of other ethnicity. 10% developed microalbuminuria, 18% hypertension, 9% had hypercholesterolaemia and 12% had evidence of diabetic retinopathy. There was a statistically significant negative correlation between the deprivation quintile and HbA1c, (r= -0.247, 95% CI -0.3914 to -0.09113, p value 0.0016).
Discussion and Conclusion: Our data has shown that higher deprivation levels correlate to a higher HbA1c as per previous reports. Despite this, our rates of vascular complications were similar or below the national average. There were no significant differences in the development of vascular complications based on ethnicity and IMD quintiles. This is likely to be due to the small number of patients who develop vascular complications before transitioning to adult services and the high numbers of patients from the most deprived quintile in our centre. Further work on national datasets is currently ongoing.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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