BSPED2024 Oral Communications Endocrine Oral Communications 4 (6 abstracts)
Health-related quality of life in severe obesity: baseline PedsQL scores from two tier 3 paediatric weight management services
Katherine Hawton 1,2 , Louise Apperley 3 , Lauren Canvin 1 , Jennifer Parkinson 3 , Meghan Owens 3 , Claire Semple 1 , Alanna Holt 1 , Shelley Easter 1 , Kate Clark 3 , Anand Ramakrishnan 3 , Ramya Gokul 3 , Ellie Clarke 3 , James O’Brien 3 , Dinesh Giri 1,2 , Senthil Senniappan 3 & Julian Hamilton-Shield 4,1
1University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom; 2University of Bristol, Bristol, United Kingdom; 3Alder Hey Children’s Hospital, Liverpool, United Kingdom; 4NIHR Biomedical Research Centre (Nutrition Theme), Bristol, United Kingdom
Background: Paediatric Quality of Life Inventory 4.0 (PedsQL) is a 23-item questionnaire completed by children and young people (CYP) and parents/carers, to measure health-related quality of life (HRQoL). It comprises four domains (Physical, Emotional, Social, School Functioning) and is scored 0-100, with higher scores indicating better HRQoL. We report baseline PedsQL scores of CYP living with severe obesity under the care of two, tier 3 Complications of Excess Weight (CEW) services.
Methods: Between March 2022-May 2024, all new patients, and parents/carers, attending two CEW services were asked to complete PedsQL questionnaires. We compared scores for CYP and parents/carers by sex, body mass index (BMI) standard deviation score (SDS) and presence of obesity-related comorbidities.
Results: 179 families completed questionnaires (95 female): CYP age range 5.3-17.9 years, mean BMI-SDS 3.58. Mean overall PedsQL scores of CYP (53.4) and parents/carers (49.6) were strongly correlated (r2=0.70). CYP rated school functioning lowest (47.1), followed by emotional functioning (50.3), social functioning (56.6) and physical functioning highest (59.1). CYP mean overall scores were lower in females (50.2) than males (57.1). CYP overall score did not correlate with BMI-SDS (r2=0.01). Neurodiversity impacted overall scores: autism spectrum disorder (with 45.5; without 56.1) and attention-deficit hyperactivity disorder (with 45.7; without 54.4). CYP living with depression (with 45.9; without 54.0) and anxiety (with 45.0; without 55.7) as expected had lower scores. CYP living with metabolic-dysfunction associated steatotic liver disease (MASLD) overall scores (47.6) were lower than those without (54.8), as were those with obstructive sleep apnoea (OSA) (41.1 vs 54.6). Neither type 2 diabetes mellitus (T2DM), or hypertension affected scores.
Conclusions: Overall, CYP and parent/carers report far lower HRQoL than data from both a healthy population (child-reported 83.9; parent-reported 84.6) and many other chronic conditions (e.g. child-reported type 1 diabetes mellitus 80.4 and cancer 72.0). Females score lower than males, and those living with neurodiversity and mental health conditions had additionally reduced HRQoL. Some obesity related complications (MASLD and OSA) associate with lower PedsQL scores. Quality of life of CYP attending CEW clinics is extremely poor and should be considered in the design of weight management services.
Volume 103
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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