Endocrine Abstracts

Introduction: Acquired primary hypothyroidism is the most common autoimmune endocrine disorder associated withT1D. It is associated with presence of antibodies called Thyroid peroxidase (TPO) and requires lifelong supplementation with Levothyroxine. NICE guidelines (NG145)1 recommends regular surveillance of thyroid levels for primary hypothyroidism every 4-6 months until puberty and then annually.Aims: To audit our practice of managing CYP with primary ...

Background: Thyroid imaging is recommended in the workup of children suspected with Congenital Hypothyroidism (CHT). Many centres in UK currently do not undertake scintigraphy routinely in CHT workup due to pitfalls such as unavailability, questionable benefit over ultrasound, result may not influence decision to treat or not, time constraints to complete scan within 5 days of starting treatment, etc.Aim: Retrospective analysis of scintigraphy data in di...

An enlarged neck mass (20x18mm), anterior to spine was incidentally discovered in foetal 20-week anomaly scan, with neck fixed in hyperextended position throughout the scan. Mother (G2P1) was asymptomatic without thyroid under or overactivity; maternal baseline thyroid function and thyroid antibodies were negative. At 21-weeks, the small stomach bubble confirmed oesophagus was compressed and swallowing compromised, with high(ish) amniotic TSH (8.5). MDT opinion was foetal bloo...

We present an 8-year-old black African girl with no significant past medical history. The patient presented with a 7-month history of profuse watery diarrhoea after moving to the UK from Nigeria. There was no history of bloody stools, abdominal pain or vomiting. The diarrhoea had worsened to approximately 10 watery episodes a day. She was noted to have progressive neck swellings with 4 kg weight loss over this time, prompting emergency department attendance. There was no histo...

Background: Hypothyroidism, a common condition, manifests with diverse clinical symptoms and is generally manageable but can be life-threatening if untreated in severe cases. It has been recognized as an uncommon cause of renal impairment and rhabdomyolysis; conditions reversible with levothyroxine replacement therapy. Here, we present the case of a teenager incidentally diagnosed with severe primary hypothyroidism due to autoimmune thyroiditis, accompanied by acute kidney inj...