BSPED2024 Poster Presentations Obesity 1 (7 abstracts)
Body composition, complications, and quality of life outcomes from a tier-3 paediatric weight management service
Anand Ramakrishnan , Louise Apperley , Pon Ramya. Gokul , Shruti Mondkar , James O’Brien , Jennifer Parkinson , Ellie Clarke , Kate Clark , Denise Swift , Kim Lund , Nicola McConnell & Senthil Senniappan
Alder Hey Children’s Hospital, Liverpool, United Kingdom
Background: Children and young people (CYP) living with obesity are at increased risk of developing various physical and mental health comorbidities. Multidisciplinary (MDT) approach for the early detection and management of comorbidities is important. We report the outcomes of the first 100 patients enrolled in the tier-3 MDT Complications from Excess Weight (CEW) service.
Methods: 100 new CYP (F=53) enrolled in the CEW service from March 2022-February 2023 were included. Baseline and the follow up data including body composition (TANITA: RD-545-SV device) and fasting metabolic profile data were analysed. Quality of life (QoL) was assessed at baseline and at follow up visits using PedsQL-4.0 questionnaires.
Results: CYP with a mean age at enrolment of 14.11 years (range 3.33-17.95 years) were followed up for a mean duration of 18.9 months (range 3-27 months). At enrolment, mean BMI-SDS was +3.68 SDS (±0.64 SD) and the mean body fat% was 51.37% (±8.42 SD). Dyslipidaemia (43%) was the most common complication. Hypertension (17%), idiopathic intracranial hypertension (8%), type 2 diabetes mellitus (8%), pre-diabetes (4%) and obstructive sleep apnoea (3%) were some of the other complications. The other comorbidities included autistic spectrum disorder (37%), ADHD (9%), learning difficulties (9%), anxiety (34%) and depression (12%). 53% of the adolescent females had menstrual concerns (oligomenorrhea/amenorrhea/menorrhagia). BMI stability was achieved in most patients and the mean BMI SDS during follow up was +3.63 SDS (±0.66 SD) and 10.3% of the CYP were able to achieve >5% weight loss. The mean body fat% reduced to 48% (±8.03 SD) [P = 0.008]. All CYP received lifestyle intervention and 59% were also on medical therapy. Parent reported total QoL scores improved from 47.35/100 to 56.04/100 (P = 0.033).
Conclusions: There is a high prevalence of comorbidities in CYP with severe obesity. BMI stabilised following MDT input and positive changes in body composition were observed. A multidisciplinary approach could help improve the health outcomes in the complex group of CYP with excessive weight.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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