Endocrine Abstracts

Case History: A 7 year old presented with 4 weeks of polyuria, polydipsia and one episode of nocturnal enuresis. The child’s past medical history was unremarkable, however, her parents reported that she was ‘less bright’ than her two siblings.Initial assessment: The child appeared well. Urine dipstick testing showed 3+ glucose. Blood glucose was 17.5, blood ketones were 0.4 and blood gas values were within the normal range.<p class="ab...

Introduction: As the prevalence of obesity increases, incidence of childhood onset type 2 diabetes mellitus (T2DM) has significantly risen, most children having a family member with T2DM. Acanthosis nigricans, marker of insulin resistance, is often noted on presentation. We describe a case of early-onset severe acanthosis nigricans and T2DM in a lean Asian Bangladeshi girl with a rare progeria partial lipodystrophy disorder, highlighting the benefit of genetic testing in unusu...

Introduction: The National Paediatric Diabetes Audit (NPDA) Report for 2022 to 2023 recommended that all children and young people should have equitable access to diabetes care, regardless of social deprivation, ethnicity, or geography.Aim: To investigate if ethnicity or socio-economic status impacted the development of vascular complications in patients with type 1 diabetes mellitus (T1DM) undergoing annual diabetes screening.Meth...

Introduction: We wanted to re-start local socials for young people with type 1 diabetes and families. In this way forming a network and peer support, accessing diabetes education in an informal environment.Method: Themed sessions, innovative party games and puzzles for the first session, things like buzz wire, toddler shape sorter blindfolded, how many pins can you get in a potato one handed-using scissors, spot the difference etc. The second session 3 m...

Objectives: The objective of this single-centre study at the University Hospitals Bristol and Weston (UHBW) is to ascertain the incidence of diabetic ketoacidosis (DKA) in children with new-onset type 1diabetes and known patients with type 1 diabetes (T1D), and to explore the reasons for DKA among these groups during the period of October 2022-October2023Methodology: The characteristics of patients who presented with DKA between October 2022 and October ...

Background: The latest NPDA data has demonstrated that technology use through Continuous Glucose Monitoring (CGM) and Hybrid-closed loop (HCL) is associated with better glycaemic control. A particular national focus is to reduce health inequalities and provide an equitable access to technology.Aims: 1. To identify the barriers for CYP with T1DM to adopting diabetes technology and address these to bridge health inequalities. 2. To look at the ethnic break...

Introduction: Between June 2023 and February 2024, 161 children and young people (CYP) with Type 1 Diabetes (T1D) were started on the Omnipod 5 automated insulin delivery pump at Leeds Children’s Hospital. Outcomes were analysed for these CYP and provisional findings are presented. As more data becomes available further statistical analysis will be performed; including comparison with other hybrid-closed loop (HCL) systems, enabling the evaluation of outcomes for all CYP ...

Question: What is the Prevalence of undiagnosed Monogenic diabetes mellitus when a formal case ascertainment protocol is followed?Background: The estimated prevalence of monogenic diabetes in the UK is 3.6%. The UNITED study (Shields et. al 2017) reported the use of urinary c-peptide:creatinine ratio (UCPCR) and autoantibodies as biomarkers to screen diabetes cohorts diagnosed at <30y and currently <50y in two UK cities. Cases found to have UCPCR...