Endocrine Abstracts

Intentional insulin overdose is an extremely uncommon but very significant paediatric emergency. <0.1% of all calls to the National Poisons Information Service in the U.K. over a 10-year-period related to insulin poisoning. No systematic studies or randomised controlled trials of the management of insulin poisoning exist. The available evidence consists predominantly of case reports. A a consequence there are no consensus-based guidelines for optimal management. I present the case of a 15-year-old female teenager with type 1 diabetes who presented acutely to the Paediatric Assessment Unit of University Hospital Wishaw in February 2022 following an intentional overdose of Levemir insulin. The presentation describes her clinical presentation and acute management. It includes a review of the available literature and offers learning points with respect to therapeutic options and additional complications of insulin overdose (e.g. hypokalaemia and glycogen hepatopathy) for clinicians who may potentially be faced with patients presenting in similar circumstances in the future. This presentation takes the form of a PowerPoint presentation.