Endocrine Abstracts

Congenital hyperinsulinism (CHI) is a rare but serious disorder characterised by a dysregulated increase in insulin secretion, leading to hypoglycaemia. Existing literature on CHI highlights the importance of early recognition and maintenance of blood glucose levels, due to the risk of neurological damage posed by uncorrected hypoglycaemia. The cases presented highlight the treatment of two brothers who developed neonatal hypoglycaemia due to diffuse CHI resulting from homozyg...

Sarcoidosis can be a multi-system granulomatous disorder usually seen in adults. Paediatric sarcoidosis is rare and can be associated with varied presentations. We present the case of an unusual presentation of sarcoidosis in a 12-year-old girl who attended with an enlarging neck swelling, hypercalcaemia and worsening renal function. Most reported cases in the Paediatric population are multi-organ and affect the lungs, liver and lymphatic system. Renal involvement with Paediat...