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Endocrine Abstracts (2024) 101 PS3-21-05 | DOI: 10.1530/endoabs.101.PS3-21-05

1Sfax Medical School, Department of Otorhinolaryngology, Habib Bourguiba University Hospital, Sfax, Tunisia; 2University of Sfax, Sfax Medical School, Lr23es01 Laboratory, Tunisia, Department of Otorhinolaryngology Head and Neck Surgery, Habib Bourguiba Hospital, Sfax, Tunisia, Tunisia; 3University of Sfax, Sfax Medical School, Lr23es01 Laboratory, Tunisia, Department of Anesthesiology, Habib Bourguiba Hospital, Sfax, Tunisia, Tunisia


Objectives: The purpose of our study is to describe the management of the a neoplastic internal jugular vein thrombosis secondary to a vesicular thyroid gland carcinoma that was not accessible through a cervical approach.

Materials and methods: We described the case of a vesicular thyroid gland carcinoma that resulted in an enormous neoplastic thrombosis of the internal jugular vein that was managed in our department using a cervico-thoracic approach.

Results: A 64-year-old female was referred to our department for a right thyroid gland nodule. It was classified as EU TIRADS V at the ultrasound and was associated to clinically and radiologically suspicious lymph nodes. Peri-operatively, we noted a thyroid gland mass was indurated at palpation. It also infiltrated the internal jugular vein massively. The latter invasion was located beyond the sternal notch and its resection was juged as not accessible using a cervical approach. Frozen-section examination confirmed a vesicular thyroid gland carcinoma. Thus, we performed a total thyroidectomy, with a bilateral central and lateral neck dissection that included the II, III and IV neck lymph nodes sectors. Since the right jugular vein was invaded by a thrombus that reached the level of the superior mediastinum, we performed a manubriotomy to reach the totality of the thrombosis and to ensure a carcinological and total resection of the invaded portion of the internal jugular vein. No post-operative complications were recorded and the patient received radioactive iodine treatment.

Conclusion : A neoplastic invasion of the internal jugular vein by a differentiated thyroid gland carcinoma is a very rare occurrence and is associated to a worse prognosis. The pre-operative diagnosis of such an occurrence is important in order to plan its management modality and the surgical procedure.

Volume 101

46th Annual Meeting of the European Thyroid Association (ETA) 2024

European Thyroid Association 

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