Endocrine Abstracts

Objectives: This study aimed to assess the prevalence and US features of TGDCs in adults on ultrasonography (US), and to assess whether the prevalence or size of TGDCs increases after RIA.

Methods: A total of 2820 patients underwent thyroid or neck US examination between July and December 2018. Among them, 54 patients were excluded owing to young age (<19 years; n = 52) and a history of radiation ther¬apy to the neck (n = 2). Eventually, 2766 patients (2148 women and 618 men, mean age±SD: 53.4±11.9 years, age range: 19–91 years) were included. The pres¬ence or absence, location, largest diameter, and shape of the TGDCs were prospectively investigated on real-time US.

Results: The prevalence of TGDC was 5.8% (n = 160) on US (mean size: 0.9±0.4 cm, range: 0.3–3.3 cm). There was no significant difference in size of TGDCs between RIA history (+) and RIA history (–) groups (mean size: 0.92±0.41 cm and 0.86±0.45 cm, respectively, P = 0.684). There was no significant difference in patient age, gender, reason for thyroid/neck US, type of thyroid surgery, and session number and application/no application of RIA between the TGDC (+) and (-) groups (P> 0.05). TGDCs were more common in the suprahyoid neck (77.5%) and the common shapes were flat-to-ovoid (43.8%) and round (41.9%).

Conclusions: RIA may not be associated with the prevalence or enlargement of TGDCs.