ETA2024 Poster Presentations Thyroid cancer treatment (10 abstracts)
1Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of Moh of Ukraine, Department of Endocrine Surgery, -, Kyiv, Ukraine; 2Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of Moh of Ukraine, Endocrine Surgery, Kyiv, Ukraine; 3Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of the Moh of Ukraine, Department of Endocrinology, -, Kyiv, Ukraine; 4Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of Moh of Ukraine, Ukraine; 5Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of Moh of Ukraine, Kyiv, Ukraine; 6Ua Center of Endocrine Surgery, Bogomolets Nmu, Kyiv, Ukraine; 7Ukrainian Scientific and Practical Center of Endocrine Surgery, Endocrinology, Kyiv, Ukraine
Introduction: Cases of locally advanced thyroid cancer can lead to spontaneous or irreversible intraoperative damage of RLN. For the correction of dysphonia with OCPS, are used static methods and the physiological reinnervation of the larynx.
Methods: A prospective monocenter study of the results of 61 cases of primary larynx reinnervation in the treatment of patients with invasive forms of differentiated thyroid cancer and initial laryngeal abduction paralysis. Used primary anastomosis of RLN - ansa cervicalis. The control was performed through 3, 6 and 12: laryngostroboscopy, VHI-30, Praat voice analysis 5.1.12. Statistical analysis - Wilcoxons one-sample test, P < 0.05.
Results: Voice improvement was observed 3-6 months after surgery: in 92% of patients were observed medialization of the vocal folds, closure of the glottis during phonation. MTF increased from 7.2 ± 1.25 sec. up to 20.4 ± 2.88 sec. The harmonic/noise ratio increased from 14.1 ± 2.69 dB to 23.3 ± 1.25 dB, and the frequency of the fundamental tone of the larynx shifted from 188.3 ± 7.51 Hz to 221.3 ± 17.86 Hz. VHI-30 results: a decrease in the total score by more than 55 points, P < 0.05.
Conclusions: Nonselective primary reinnervation of the larynx does not restore the coordinated mobility of the vocal fold, but improves voice quality.