ETA2024 Poster Presentations Thyoid cancer case reports-1 (9 abstracts)
Intrathyroidal parathyroid carcinoma: a case report
Wejdan Mohamed Trabelsi 1 , Mohamed Dhaha 2 , Fatma Haffeni 2 , Rim Baraham 2 , Alia Methnani 3 , Souheil Jbali 4 , Sawsen Dhambri 2 & Skander Kedous 5
1Salah Azaiez Institut, Ent, Tunis, Tunisia; 2Salah Azaeiz Institute, Ent, Ent, Tunis, Tunisia; 3Salah Azaiez Institute, Ent, Ent, Tunis, Tunisia; 4Salah Aziez Institute, Ent, Ent, Tunis, Tunisia; 5Salah Azaeiz Institue, Ent, Ent, Tunis, Tunisia
Introduction: Parathyroid carcinoma (PTC) is a very rare neuroendocrine malignancy. It accounts for approximately 1% of primary hyperparathyroidism. Intrathyroidal localization is extremely rare.
Aim : On the basis of a case report and literature data, we describe the particularities of this rare pathological entity.
Observation: 53-year-old female patient with history of recent venous thrombosis referred for management of a left thyroid nodule discovered by chance during a CT scan ordered to investigate severe anemia associated with secondary osteolytic bone lesions. Clinical examination revealed a 1 cm right paramedian basi-cervical swelling and an anodular left lobe. Cervical ultrasound showed a left thyroid nodule. Preoperative workup revealed normal calcium and phosphorus levels and a normal renal workup. The patient underwent left loboisthmectomy with extemporaneous examination showing atypical cells with vesicular neoplasms. The parathyroid glands were not visualized on the left side, and totalization was performed due to the patient’s anaesthetic difficulties. The definitive anatomopathological examination with immunohistochemical study concluded to a parathyroid carcinoma of intrathyroidal localization. Postoperatively, the patient developed hypocalcemia requiring parenteral calcium supplementation with normal PTH value.
Conclusion: PTC is a very rare malignancy. Intrathyroidal localization is exceptional and presents a diagnostic challenge in the absence of clinical and morphological specificities.
Volume 101
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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