Endocrine Abstracts

Introduction/Aim: Central sensitivity to thyroid hormones refers to the sensitivity of the hypothalamic-pituitary-thyroid (HPT) axis to changes in circulating free thyroxine (fT4). The relationship between fT4 levels and iodine intake is complex. The aim of the present study was to assess central sensitivity to thyroid hormones in pregnancy against iodine intake.Materials & Methods: Data were collected from 138 pregnant women (with a mean age of 29.8...

Objective: No consensus has been reached yet on whether iodine supplementation should be recommended also in pregnant women with Hashimoto’s thyroiditis who are receiving levothyroxine (LT4) therapy. We aimed to evaluating the iodine status in a sample of pregnant women residing in the Veneto region of Italy and suffering from autoimmune thyroiditis. Here we present our preliminary results.Methods: 81 pregnant women with Hashimoto’s thyroiditis...

Objectives: The association between thyroid function variations and body mass index (BMI) has been described in the adult population in several studies: higher TSH values and lower FT4 values, while still within reference range, have been correlated with higher BMI values. The aim of the study was to assess thyroid hormones variations in relation to body weight in pregnant women without thyroid diseases.Methods: In this prospective study, thyroid functio...

It is well established that due to enhanced iodine/thyroxine requirement during pregnancy women with inadequate iodine intake are at high risk of iodine deficiency (ID). However, the relative impacts of mild & moderate ID are yet debated. General population inIndia has been declared iodine-sufficient (93%, vide WHO) but we found 70-90% pregnant women from 3 States, iodine-deficient(UIC <150 mg/l).Objective: To assess the extent of ID and...

Objective: Pregnant women worldwide are at risk for mild iodine deficiency (ID) due to transfer of iodine through placenta, increased glomerular filtration of iodine and higher maternal thyroid hormone production for foetal needs. Studies show that mild ID involves normal thyroid hormone levels but may lead to increased thyroglobulin levels resulting from an increased maternal thyroid volume through changed thyroid metabolism. When assessing thyroid hormones during pregnancy, ...

Context: Iodine is an important mineral essential for thyroid function and for normal development of the fetus. There is growing evidence that iodine insufficiency is still a major health issue globally.Objective: The main aim of this study was to look for ethnic differences in iodine status in pregnant women based on urinary iodine concentration (UIC) and food frequency questionnaires (FFQ). Furthermore, we assessed the influence of iodine status on thy...

Background: Pregnancy causes significant changes in regulation of the hypothalamus-pituitary-thyroid (HPT) hub and extrathyroidal thyroid chemical digestion. Thus, after effects of thyroid capability tests contrast in pregnant ladies contrasted and nonpregnant ladies, and trimester-explicit reference scopes of TSH and free T4 (fT4) have been proposed. Most studies of thyroid function changes during pregnancy use a cross-sectional design comparing means between groups rather th...

Introduction: Iodine supplementation is recommended for populations at risk in countries without sufficient iodized salt coverage, as Portugal. Pregnancy is a time of particular susceptibility to malnutrition. In Portugal, despite the recommendation (issued in 2013 by the health authorities) to supplement iodine during preconception, pregnancy and lactation, pregnant women are still iodine deficient.Objectives: To characterize the nutritional composition...

Background and objectives: In the period 2022-2023, a multicentre study coordinated by the Italian National Observatory for Monitoring Iodine Prophylaxis (OSNAMI), was launched in 8 Italian regions representative of the Northern (Lombardy, Veneto, Liguria), Central (Tuscany, Lazio) and Southern Italy and Islands (Sicily, Calabria, Sardinia) with the aim of evaluating iodine nutrition in pregnant women (n = 400/region) and thyroid function in the offspring. Here we pre...

Increase of patients submitted to assisted reproduction techniques (ART) and to the high prevalence of thyroid disorders in the fertile age, this survey aimed to evaluate the current management of these women by the Italian thyroidologists. A short questionnaire was sent to all members of the AIT. The questions concerned the out-patients management of women of childbearing age with thyroid diseases. According to our results, there is a clinic dedicated to the management of pat...