Endocrine Abstracts

Introduction: Amiodarone is a widely used agent for life-threatening arrhythmias. Although amiodarone is associated with few side effects, including thyroid dysfunction in 15-20% of patients. Amiodarone-induced thyrotoxicosis (AIT) is a major adverse effect that can cause recurrence of arrhythmias and exacerbation of heart failure. It is a challenging diagnosis that affects 0,003% to 10 % of patients taking amiodarone. Type I AIT is seen in patients with preexisting thyroid di...

Objective: Our aim was to assess the prevalence of the metabolic syndrome (MetS) and its components in patients with controlled Graves’ disease (GD).Methods: This was a cross-sectional study involving 95 consecutive patients with GD referred to our tertiary care inpatient clinical center meeting the following inclusion criteria: controlled hyperthyroidism, treatment with antithyroid drugs, untreated Graves’ orbitopathy (GO), if present. Patient...

Objective: Mental fatigue (MF) is part of the concept of mental illness but is poorly established. Pathological MF occurs in many diseases and greatly reduces both quality of life (QoL) and work capacity. In Graves’ disease (GD) that often affects women of working age, about 40% of patients show MF after the acute symptoms have been treated. MF can occur alone, but also in combination with depression or anxiety and women are more than twice as likely as men to be on long-...

Objectives: Abnormal liver blood tests (ALBTs), neutropenia (NEU) and thymic hyperplasia (TH) are new features of Graves’ disease (GD). Our objectives were: a) to calculate the accuracy of TH in discriminating between Graves’ and non-Graves’ thyrotoxicosis, compared to ALBTs, NEU and Graves’ orbitopathy (GO); b) to explore the outcome of GD associated TH and non-GD associated TH.Methods: We prospectively analyzed consecutive adult pat...

Context: Graves’ disease (GD) is the most common cause of hyperthyroidism, usually affecting women.Objective: To asses the thyroid function and volume in GD patients treated with anti-thyroid drugs (ATD) in different regimens.Patients and Methods: The study included 128 adult patients (104 females (F), 24 males (M)) with newly diagnosed or relapsed GD treated medically. Patients were consecutively admitted to a tertiary endocr...

Background: Graves’ disease (GD) mainly affects women in all age groups. Although most patients improve with treatment, patients still often experience cognitive and psychological symptoms. The ambiguity surrounding these persistent mental symptoms contributes to frustration for both patients and healthcare professionals. The study aims to provide in-depth insights into how healthcare professionals perceive the care of patients with GD. Through interviews, we aim to under...

Introduction: Graves’ disease (GD) is the foremost cause of hyperthyroidism, and antithyroid drugs (ATD) are the first line of treatment, with around 40% of relapse after withdrawal. Therefore, radioiodine treatment (RAI) or a second course of ATD is indicated. However, the impact of those treatments on quality of life (QoL) is not well known.Objectives: Investigate the impact of ATD and RAI in the QoL of relapsed GD patients....

Objective: This study investigates the effectiveness and additional value of contrast-enhanced ultrasound (CEUS) in differentiating between destructive thyroiditis and hyperproduction states in patients with diffuse thyroid disease.Methods: In this research, 56 patients diagnosed with hyperthyroid diffuse disease underwent evaluation through CEUS, alongside conventional ultrasound and standard diagnostic tests. We focused on qualitative CEUS parameters l...

Objective: βenign thyroid diseases are common and can cause physical and mental symptoms. Although they may not affect a patient’s life expectancy, they adversely affect Quality of Life (QoL). Thyroidectomy, even performed for benign thyroid conditions, is an invasive procedure that can further affect QoL. The present study aims to detect changes in thyroid-related QoL in patients with benign thyroid diseases who undergo thyroidectomy.Methods: ...