Endocrine Abstracts

Background: Papillary thyroid microcarcinoma (PTMC) is characterized by its favorable prognosis and potential for active surveillance (AS) as a management option. However, the presence of cervical lymph node (LN) metastasis, especially lateral LN metastasis, significantly impacts both management and prognosis. This study identified predictors of lateral LN metastasis by analyzing pre-operative ultrasonographic findings alongside clinicopathological factors.<p class="abstex...

Introduction: Thyroid nodules are a frequent and mostly benign pathology. Failure to recognize a cancer remains a major concern for any physician confronted with this pathology. Fine needle aspiration cytology (FNAC) is the key to diagnosis. The aim of our study was to describe the results of cytological examination in determining the histological nature of thyroid nodules.Methods: We conducted a cross-sectional, retrospective, and descriptive study, spr...

Background: Thyroid cancer can be detected in early stage using ultrasonography, but there are also questions about the necessity of screening tests due to its relatively high survival and low recurrence rate compared to other cancers. In this study, a cost-effectiveness analysis of thyroid cancer was conducted for better patient selection with cases diagnosed by ultrasound, as well as cases diagnosed through the presence of symptoms.Methods: For the ana...

Objectives: The aim of this study was to evaluate the diagnostic value of four commonly utilized ultrasound (US) RSSs (the American College of Radiology [ACR], European [EU], Korean [K] TI-RADSs and American Thyroid Association [ATA] US-based RSS criteria) in combination with activating point mutations of the RAS genes (NRAS, HRAS, and KRAS) for detecting thyroid carcinoma in cytologically indeterminate and suspicious for malignancy thyroid nodules.Metho...

Objectives: Thyroid nodules are common and mostly benign, but around 7-15% of them account for thyroid cancers. In recent years, a significant increase in the detection rate of thyroid nodules has been observed. Ultrasonography (US) has become a valuable tool in thyroid nodules malignancy risk assessment, however, it might lead to thyroid cancer overestimation and unnecessary biopsies. The aim of our study was to create a machine-learning prognostic model for thyroid nodules m...

Introduction: F-18 FDG PET/CT has a valuable role in the initial workup for solid tumors, including lung adenocarcinoma and head and neck squamous cell carcinoma. However, its role in the staging of thyroid carcinomas remains contentious. Present guidelines advocate for the deployment of F-18 FDG PET/CT in instances of recurrence detection, particularly in patients demonstrating elevated serum thyroglobulin levels with a concurrent negative radioiodine whole body scan. Routine...

Objective: Neck US is essential in the preoperative endocrinological evaluation of malignant thyroid nodules and determining surgical approach. Extrathyroidal extension (ETE) in DTC is a significant risk factor for recurrence. Our study aim is to assess ultrasonographic features predicting minor ETE.Method: In our two-center prospective study, we recorded US videos of DTC nodules adjacent to the capsule, with no thyroid parenchyma between the capsule. Ex...

Aim/Introduction: [18F]fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) has gained an important role in the preoperative diagnosis of patients with primary hyperparathyroidism (pPHP). In these patients, thyroid nodules are frequently found on preoperative ultrasound. FCH PET/CT provides a high negative predictive value to reliably rule out cancer in thyroid nodules with low uptake. However, more than half of benign thyroid nodules have b...

Backgrounds: With increasing use of 18F-fluorodeoxyglucose positron emission tomography (FDG PET) in the clinical field, thyroid nodules are one of the common incidental findings. It is reported that about one third of these nodules are proven to be malignant nodule. In this study, efficacy of quantitative PET indexes in predicting the cytopathology of thyroid nodules was evaluated.Methods: A total of 338 patients with thyroid nodules det...

Aim: To investigate the clinical, paraclinical and histological characteristics of Bethesda 3 and 4 nodules and determine their malignancy rate.Methods: We conducted a retrospective descriptive study including 52 patients who underwent surgery for Bethesda class 3 and 4 thyroid nodules at the ENT department over a 7-year period (2016-2022).Results: The mean age of our patients was 51 years, with a ratio of 0.13. The most common pre...

Introduction: Borderline thyroid tumors, characterized by their indistinct status between benign and malignant forms, pose significant diagnostic and therapeutic challenges. This study aims to elucidate effective diagnostic and management strategies for these tumors, enhancing patient outcomes.Methods: Our study employed a retrospective analysis design, spanning several years, focusing on various borderline thyroid tumors, including Hyalinizing Trabecula...