Endocrine Abstracts

Objective: In patients with differentiated thyroid carcinoma, whole-body scans (WBS) are usually assessed 48 h after radioiodine administration. The aim of the study is to correlate the intuitive assessability after different time points with the standardized diagnostic algorithm.Methods: Data were available from 35 consecutive, prospectively treated (97% exogenous TSH stimulation) patients in whom WBS were acquired at up to 6 time points (6, 24, 48, 72,...

Purpose: The generally good prognosis of low- and intermediate-risk differentiated thyroid cancer (DTC) underscored the need to identify those few patients who relapse. Methods: Records of 299 low- or intermediate-risk DTC patients (mean follow-up 8.2 ± 6.2 years) were retrospectively reviewed. The sample was classified following the American Thyroid Association (ATA) Dynamic Risk Stratification (DRS) system.Results: After class...

Aim: Papillary thyroid carcinoma (PTC) is a malignancy originating from the follicular epithelium of the thyroid gland. Psammoma bodies (PBs), structures characterized by concentric layers surrounding a calcified focus, are a pathognomonic finding in PTC. The precise mechanism of PB formation, as well as their association with clinical presentation and prognosis, remains an area of active investigation. This study aimed to elucidate the influence of PB presence on histopatholo...

Introduction: Cutaneous metastases are a rare event in thyroid cancer (TC), generally occurred in the context of a metastatic and progressive disease and generally represents a poor prognostic factor. In the subgroup of skin metastases, very rare are the subcutaneous localizations to the thyroidectomy scar, described only in few papillary (PTC) and follicular TC (FTC) cases. We reported a series of 6 cases of PTC/FTC patients with subcutaneous metastases localized both on thyr...

Objectives: The majority of DTC cases has excellent prognosis; approximately 5% may develop metastatic disease not responding to radioiodine treatment (RAI-R DTC). There are few reports of real-life experience concerning their clinical course.Methods: We conducted a retrospective study in metastatic RAI-R DTC patients focusing on the clinical characteristics at diagnosis, the location and time interval of the appearance of metastatic lesions, the treatme...

Background: The use of radioiodine treatment (RAI) in cases categorized as low to intermediate risk papillary thyroid cancer (PTC) is still uncertain. Current guidelines recommend a selective use of RAI based upon the clinicopathologic features of each case. In this context, postoperative serum thyroglobulin (pTg) could be useful but the predictive role for recurrence and the optimal cut off value to be applied is not clearly established.Objectives: To d...

Objectives: Differentiated thyroid cancer (DTC) is rare in childhood and adolescence. However, its incidence increases by 1.1% per year, rendering it the most common pediatric endocrine neoplasia, representing 3% of all pediatric malignancies. The aim of the study is to present the data of pediatric patients with DTC followed in our institution.Methods: Patients with DTC who were diagnosed and treated in our division between 2017 and 2024 were enrolled i...

Objective: Imaging-guided percutaneous core needle biopsy (PCNB) is currently the most common technique for the investigation of potentially malignant bone lesions. It allows precise needle placement and better visual guidance, leading to improved diagnostic accuracy. Needle tract seeding (NTS) is a rare complication of biopsies in general, and its true incidence remains unknown. This study aimed to assess the risk of NTS in patients with thyroid cancer who underwent bone biop...

Objective: The aim of this study was to evaluate the response to initial postoperative radioactive iodine therapy (I-131) in patients with papillary thyroid microcarcinoma.Methods: This was a retrospective study including 123 patients treated for papillary thyroid microcarcinoma with low to intermediate-risk, between 2012 and 2020. These patients underwent total thyroidectomy followed by radioactive iodine therapy (I-131). Clinical examination, thyroglob...

Recently, we have witnessed an increase in the number of new thyroid cancer (TC) cases and thyroid surgeries. Both the ATA 2015 and 2022 Polish guidelines allow sparing treatment in low-risk TC. Nevertheless, most patients are qualified for total thyroidectomy. The aim of the study was to analyze the possibility of preoperative diagnosis of low-risk TC based on ultrasound examination (US).Material and method: A retrospective analysis involved 1043 patien...