Endocrine Abstracts

30 year female diagnosed with AML at the age of 3. On diagnosis in 1996 had recurrence of AML 1998 had Bone marrow transplant with Total body irradiation and cyclophosphamide preconditioning 1998. She had suffered with post transplant cardiomyopathy (1999) Primary ovarian insufficiency and Childhood growth hormone replacement therapy (discontinued 2010) and recently found to have possible post irradiation induced Hypercalcaemia. She weighs 40 kg, height 4 ft 11 inches and BMI 17.8. Her dexa scan showed (Osteopenia)- spine T-score -1.1, hip T-score - 1, Bone mineral density 0.881 g/cm². She has not sustained any fracture. She was initially started on oral contraceptive pill for many years and but has been changed to Fomestin 2/10 mg 5 years ago and she continue to have withdrawal bleed and with no h/o mood swings and sided effects. She switched her to Evoral sequi patch for a year but sustained rash with patches and stopped using it 1 year ago now has moved to Oestrogel Pump750 micrograms/actuation two pumps every day for two weeks followed by Oestrogel two pumps and Utrogestan capsule 200 mg for next two weeks and continue to have withdrawal bleed. she is not keen for pregnancy and never been pregnant.