ECE2024 Poster Presentations Diabetes, Obesity, Metabolism and Nutrition (130 abstracts)
Characteristics of presentation and management of people with hypoglycaemia while on continuous glucose monitoring devices - pilot data from DEKODE hypoglycaemia study
Charles Page 1 , Aashritha Buchipudi 1 , Ahmed Iqbal 2 , Amanda Ling Jie yee 1 , Haaziq Sheikh 1 , Lakshmi Rengarajan 3 , Ninoshka Merchant 1 , Pranav Viswanath Iyer 1 , Rajeev Raghavan 4 & Team Dekode 3
1University of Birmingham Medical School, Birmingham, United Kingdom; 2Department of Oncology & Metabolism, University of Sheffield & Sheffield Teaching Hospitals, Sheffield, United Kingdom; 3Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom; 4Wolverhampton Diabetes Endocrine Centre, New Cross Hospital, Wolverhampton, United Kingdom
Background: Continuous glucose monitoring (CGM) is an increasingly important diabetes technology that has the potential to facilitate the avoidance of low glucose values. However, there is a paucity of information on admitted patients’ characteristics, management, and outcomes of those admitted with hypoglycaemia despite being on CGM.
Objective: To explore the characteristics of the patient population, precipitating factors and outcomes of people admitted with hypoglycaemia while on CGM.
Methods: This retrospective study was conducted from October 2023 to January 2024 across five hospitals in the UK. All adults aged >18 years admitted to hospitals with hypoglycaemia while on CGM from November 2022 to October 2023 were included in the study. Data on sociodemographic, precipitating factors, management, outcomes and total time spent during hypoglycaemic episodes were collected. Data was analysed on SPSS 29.0.
Results: We identified 39 episodes of hypoglycaemia, with 37 occurrences in individuals with type 1 diabetes and 2 in those with type 2 diabetes. 34 episodes occurred while the person was an inpatient in the hospital. The median (interquartile) age was 49.0 (36.0-50.0) years. Their Charlson comorbidity index was 4 (4-6). 79.5% were men. The median (interquartile) HbA1c before admission was 98.0 (60.0-98.0) mmol/mol. 79.5% were level 1, 10.3% were level 2, and 10.3% were level 3 hypoglycaemia. 48.7% of episodes were due to missed meals. Patients spent 26 (16.0- 124.0) min in hypoglycaemia during these episodes. 7.7% of people received glucagon either at home, in an ambulance, or in a hospital for hypoglycaemia. However, only 5.1% were prescribed glucagon upon discharge.
Conclusion: The majority of hypoglycaemia was due to missed meals. Despite spending a median of 26 minutes in hypoglycaemia, only a small percentage received glucagon, and a mere 5.1% were prescribed glucagon upon discharge. These findings underscore the need for enhanced education and proactive management strategies for individuals on CGM to effectively prevent and address hypoglycaemic episodes, potentially improving patient outcomes and overall diabetes care.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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