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Endocrine Abstracts (2024) 99 P196 | DOI: 10.1530/endoabs.99.P196

ECE2024 Poster Presentations Late-Breaking (77 abstracts)

Assessing medication adherence and unravelling the reasons for non-adherence among patients with diabetes mellitus

Mukhammadbektosh Khaydarov 1 , Timurkhon Tillakhujaev 2 , Malika Oblokulova 2 , Asadbek Sultonov 2 , Zulaykho Shamansurova 2,3 & Zamira Khalimova 4


1Central Asian University - CAU, Тоshkent; 2Central Asian University, Endocrinology, Tashkent, Uzbekistan; 3Institute Biophysics and Biochemistry at the NUUz, Metabolomics, Tashkent, Uzbekistan; 4Republican Specialised Scientific Practical Medical Centre of Endocrinology, Endocrinology, Tashkent, Uzbekistan


Introduction: Chronic diseases pose an escalating health burden worldwide, affecting individuals across all age groups and socioeconomic backgrounds. The number of people living with diabetes has nearly quadrupled over the past four decades. The aim of our study was estimation of the level of medication (meds) adherence among DM type 2 patients whose admitted into Republican Specialised Scientific Practical Medical Centre of Endocrinology in Uzbekistan.

Material and methods: Pilot testing were conducted in 120 patients with DM in age between 18 – 75 years old. Type 1 DM – 7%. All people after their agreement and sign consent form, were questioned by using Morisky Medication Adherence Scale (MMAS) after approval from the local Scientific and Ethical Committees. All data was collected using Google template and undergo to statistics.

Results: Data analysis showed that 71% of observed patients were on retirement, 3% living alone, other lives with their family, female patients consisted big part of the group (65%). DM duration >10 years in 65%, between 2 to 10 years in 34%, less than 2 years in 1%. Despite the most of the people followed to healthy habits, 12% among them were smokers and 4.7% were alcohol users, 59% of them have HTN, 40% have CVD, 30% arthritis, 2% no any additional diseases. Only 6% of them achieved good glycemic control, 11% acceptable according to HbA1c level and other were in poor glycemic control. Reason for incompliance to taking prescribed medications were forgetting to take in 28.5%, in 50% careless, in 51% skipped the time to take of medication, 29% stop when fill worse, 46% experienced misunderstanding instruction, 24% stop due to side effects, 38% can change dosage without doctors. Interestingly, 48% of them intentionally stop taking meds, 5% do not take because not understand, 5% afraid to use meds, 8% just forget about Meds, 3% stop after feeling better, 2% due to delivery issues, 6% stop without reasons, 3% stop taking med because of long duration.

Conclusion: Leading cases of not reaching the good glycemic control among people with DM is adherence to prescribed medications due to their careless, misunderstanding, skip the time, stop when feeling worse or better, forgetting, or without any reason. It is necessary educate patients to more tight self-control of adherence to achieve better glycemia in patients with DM.

Volume 99

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

European Society of Endocrinology 

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