Endocrine Abstracts

Obesity is accompanied by chronic diseases including cardiometabolic diseases. Obesity is also an independent factor of renal risk that deserves to be taken into account. The aims of our work were to determine the prevalence of chronic kidney disease related to obesity independently of all other usual risk factors and to describe its epidemiological characteristics in our population. We conducted a prospective descriptive and analytic study over a period of 12 months in 38 patients over 18 years of age, with a BMI> 30 Kg/m² and without diabetes, hypertension, or other apparent cause chronic kidney disease, collected at the consulting service of the Military Hospital Avicenna of Marrakech. The average age of our patients was 38 years with a female predominance (sex ratio (m/w) of 0.80). The average BMI was 35.35 kg/m²;, the average TT was 98.61 cm with android obesity in 88.2% of men and 85.7% of women. Dyslipidemia was found in 68.42% of patients, hyperuricemia in 18.42%, microalbuminuria in 13.15%, macroalbuminuria in 7.89% and hematuria in 2.6%. Glomerular hyperfiltration was present in 13.15% of cases and no patient had a GFR <60 ml/min/1.73m². The prevalence of chronic kidney disease among obese people in our population was 10.5%. Older obese patients with high BMI, hypertriglyceridemia, hypercholesterolemia, and hyperLDLemia were the most affected, with statistically significant differences between the 2 groups of patients with and without chronic kidney disease (P<0.05). The results of our study warn of the need for cost-effective and well-adapted prevention measures to reverse the growing epidemic of obesity in the world.

Keywords: Obesity - Chronic kidney disease - Epidemiology - Risk factors