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Endocrine Abstracts (2024) 99 EP798 | DOI: 10.1530/endoabs.99.EP798

1National Institute of Nutrition and Food Technology, Department A; 2National Institute of Nutrition and Food Technology, C, Tunis; 3National Institute of Nutrition and Food Technology


Introduction: Depression and type 2 diabetes are often associated, but until now their exact relationship has remained unclear. The aim of our work was to evaluate the prevalence of depression in type 2 diabetic subjects and to determine its impact on glycemic control.

Methods: This was a descriptive cross-sectional study conducted in the National Institute of Nutrition. We included 400 type 2 diabetic patients. To assess depression, we used the Hospital Anxiety And Depression Scale (HADS). A score of 11 or above was considered positive.

Results: The mean age of our patients was 59.19±8.81 years. Female predominance was noted (67.5%). The mean age of diabetes was 13.31±7.9 years, with a mean HbA1c of 10.03±2.03% and fasting plasma glucose of 11.26±4.81 mmol/l. The majority of patients had good medication compliance (82.3%), with 13.75% not accepting their diabetes. Obesity was present in 44.5% of subjects. The prevalence of depression was 36.8%. The presence of this psychological disorder was positively associated with female gender (P<0.001), obesity (P=0.004), diabetes duration (P=0.012), diabetes acceptance (P=0.02), diabetic retinopathy (P=0.02), peripheral neuropathy (P=0.001) and vegetative neuropathy (P=0.03).

Conclusion: The large number of diabetic patients with definite depression calls for systematic screening of all diabetics for this psychiatric disorder, for better management and quality of life.

Volume 99

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

European Society of Endocrinology 

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