Endocrine Abstracts

Adrenal tumors are not uncommon in endocrine practice. We collected retrospective data from our clinical records of our patients with adrenal tumors from 2021 January to 2023 January. There were a total 20 patients; males 10 (50%) and females 10 (50%). Mean age was 47.4±10.65 years and average BMI was 26.57±4.94. Hypertension was seen in 13 patients (65%) and diabetes in 9 patients (45%). Nonfunctioning adrenal adenomas (NFAAs) were seen in 12 patients (60%) and functioning adenomas seen in 8 patients (40%). Among NFAAs, 9 patients (75%) had left sided, 2 patients (16.6%) had right sided and 1 patient (8.3%) had bilateral adrenal adenomas. All NFAAs were detected as incidentalomas. Mean size of NFAA was 21.92 mm (in greatest dimension). Among patients with NFAAs, 1(8.33%) went for surgery and other 11 patients (91.67%) underwent conservative management. Among functioning adrenal adenomas, 7 patients (87.5%) had left sided and 1 patient (12.5%) had right sided adrenal adenoma. All functioning tumors were unilateral. Pheochromocytoma was seen in 2 patients (10% of all adrenal tumors), aldosterone producing tumor (Conn’s syndrome) was seen in 3 patients (15% of all adrenal tumors), cortisol secreting tumor (nonACTH dependent Cushing’s syndrome) was seen in 3 patients (15% of all adrenal tumors). Mean size of pheochromocytoma tumors was 35.55 mm (in greatest dimension), aldosterone producing tumors was 14.5mm (in greatest dimension) and cortisol secreting tumors was 26.67mm (in greatest dimension). One patient had MEN 2A syndrome (medullary thyroid carcinoma and pheochromocytoma). Of functioning adrenal adenomas, 6 patients (75 %) went for surgery. All the patients underwent laparoscopic surgery. Cure was achieved in all patients who underwent surgery. One patient with an aldosterone producing tumor was managed with medical treatment (spironolactone) and the patient with MEN 2A syndrome had undergone total thyroidectomy for medullary thyroid carcinoma but died before pheochromocytoma surgery could be done.